83 Result(s)

Article

Pseudoendocrine sarcoma: clinicopathologic, molecular, and epigenetic features of one case

Pseudoendocrine sarcoma (PES) is a recently described neoplasm typically arising in paravertebral soft tissues. Histologically, PES resembles well-differentiated neuroendocrine tumors but lacks expression of e...

M. Adelita Vizcaino, Andrew L. Folpe, Henry Huffman, Ripul R. Panchal… in Virchows Archiv (2023)

Article

Hybrid tumors with perineurioma components: a systematic review of the literature and illustrative case

Hybrid peripheral nerve sheath tumors (HPNST) are a newly recognized class of peripheral nerve sheath tumor, composed of at least two areas characteristic of perineurioma, schwannoma, or neurofibroma. The lite...

Karina A. Lenartowicz, Dileep D. Monie, Kimberly K. Amrami… in Acta Neurochirurgica (2023)

Chapter

Histopathology of Meningiomas

Meningiomas are considered to arise from meningothelial cells, whose cytomorphology they recapitulate. In this chapter, we review the characteristic histological features of meningioma, including classic archi...

Aditya Raghunathan, Caterina Giannini in Biological and Clinical Landscape of Meningiomas (2023)

Chapter

Glioneuronal and Neuronal Tumors of the Central Nervous System

(GNTs) are composed of neural and glial elements frequently located in is the main symptom and diagnosis mostly occurs before I tumors, transformations and forms exist. Their common association is...

Matteo Martinoni, Viscardo Paolo Fabbri… in Human Brain and Spinal Cord Tumors: From B… (2023)

Article

Expanded analysis of high-grade astrocytoma with piloid features identifies an epigenetically and clinically distinct subtype associated with neurofibromatosis type 1

High-grade astrocytoma with piloid features (HGAP) is a recently recognized glioma type whose classification is dependent on its global epigenetic signature. HGAP is characterized by alterations in the mitogen...

Patrick J. Cimino, Courtney Ketchum, Rust Turakulov, Omkar Singh… in Acta Neuropathologica (2023)

Article

Molecular and clinicopathologic characteristics of gliomas with EP300::BCOR fusions

Zhichao Wu, Sharika Rajan, Hye-Jung Chung, Mark Raffeld… in Acta Neuropathologica (2022)

Article

Failure of human rhombic lip differentiation underlies medulloblastoma formation

Medulloblastoma (MB) comprises a group of heterogeneous paediatric embryonal neoplasms of the hindbrain with strong links to early development of the hindbrain^1–4. Mutations that activate Sonic hedgehog signallin...

Liam D. Hendrikse, Parthiv Haldipur, Olivier Saulnier, Jake Millman… in Nature (2022)

Article

ABP1–TMK auxin perception for global phosphorylation and auxin canalization

The phytohormone auxin triggers transcriptional reprogramming through a well-characterized perception machinery in the nucleus. By contrast, mechanisms that underlie fast effects of auxin, such as the regulati...

Jiří Friml, Michelle Gallei, Zuzana Gelová, Alexander Johnson, Ewa Mazur… in Nature (2022)

Article

Recurrent ACVR1 mutations in posterior fossa ependymoma

Drew Pratt, Calixto-Hope G. Lucas, Pavalan Panneer Selvam… in Acta Neuropathologica (2022)

Article

DNA methylation analysis of glioblastomas harboring FGFR3-TACC3 fusions identifies a methylation subclass with better patient survival

Zhichao Wu, Osorio Lopes Abath Neto, Tejus A. Bale… in Acta Neuropathologica (2022)

Article

High-grade glioma with pleomorphic and pseudopapillary features (HPAP): a proposed type of circumscribed glioma in adults harboring frequent TP53 mutations and recurrent monosomy 13

Tumors of the central nervous system (CNS) often display a wide morphologic spectrum that has, until recently, been the sole basis for tumor classification. The introduction of the integrated histomolecular di...

Drew Pratt, Zied Abdullaev, Antonios Papanicolau-Sengos… in Acta Neuropathologica (2022)

Article

Subgroup and subtype-specific outcomes in adult medulloblastoma

Medulloblastoma, a common pediatric malignant central nervous system tumour, represent a small proportion of brain tumours in adults. Previously it has been shown that in adults, Sonic Hedgehog (SHH)-activated...

Hallie Coltin, Lakshmikirupa Sundaresan, Kyle S. Smith… in Acta Neuropathologica (2021)

Article

Histopathology and prognosis of germ cell tumors metastatic to brain: cohort study

Germ cell tumors (GCTs) are uncommon neoplasms predominantly arising in midline tissues. The prognostic significance of histopathology in predicting metastatic GCT behavior is poorly understood.

Hirokazu Takami, Christopher S. Graffeo, Avital Perry… in Journal of Neuro-Oncology (2021)

Article

Intracranial angiomatoid fibrous histiocytoma with rhabdoid features: a mimic of rhabdoid meningioma

Angiomatoid fibrous histiocytoma (AFH) is an uncommon soft-tissue neoplasm that arises mostly in the extremities of young people and generally carries a good prognosis. Intracranial location is unusual and fre...

M. Adelita Vizcaino, Caterina Giannini, Howard T. Chang… in Brain Tumor Pathology (2021)