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  1. Article

    Open Access

    Orphan receptor GPR110, an oncogene overexpressed in lung and prostate cancer

    GPR110 is an orphan G protein-coupled receptor--a receptor without a known ligand, a known signaling pathway, or a known function. Despite the lack of information, one can assume that orphan receptors have imp...

    Amy M Lum, Bruce B Wang, Gabriele B Beck-Engeser, Lauri Li, Namitha Channa… in BMC Cancer (2010)

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  2. Article

    Open Access

    Pvt1-encoded microRNAs in oncogenesis

    The functional significance of the Pvt1 locus in the oncogenesis of Burkitt's lymphoma and plasmacytomas has remained a puzzle. In these tumors, Pvt1 is the site of reciprocal translocations to immunoglobulin loc...

    Gabriele B Beck-Engeser, Amy M Lum, Konrad Huppi, Natasha J Caplen… in Retrovirology (2008)

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  3. Article

    Open Access

    Retroviral activation of the mir-106a microRNA cistron in T lymphoma

    Retroviral insertion into a host genome is a powerful tool not only for the discovery of cancer genes, but also for the discovery of potential oncogenic noncoding RNAs. In a large-scale mouse T lymphocyte tumo...

    Amy M Lum, Bruce B Wang, Lauri Li, Namitha Channa, Gabor Bartha… in Retrovirology (2007)

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  4. No Access

    Article

    Neutrophil rolling altered by inhibition of L-selectin shedding in vitro

    THE L-selectin adhesion molecule is involved in guiding leuko-cytes to sites of inflammation1. L-selectin is cleaved by an unusual proteolytic activity at a membrane-proximal site resulting in rapid shedding from...

    Bruce Walcheck, Julius Kahn, Joseph M. Fisher, Bruce B. Wang, R. Spencer Fisk… in Nature (1996)