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Open AccessOrphan receptor GPR110, an oncogene overexpressed in lung and prostate cancer
GPR110 is an orphan G protein-coupled receptor--a receptor without a known ligand, a known signaling pathway, or a known function. Despite the lack of information, one can assume that orphan receptors have imp...
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Open AccessRetroviral activation of the mir-106a microRNA cistron in T lymphoma
Retroviral insertion into a host genome is a powerful tool not only for the discovery of cancer genes, but also for the discovery of potential oncogenic noncoding RNAs. In a large-scale mouse T lymphocyte tumo...