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524 Result(s)
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Article
Verhandlungen Ärztlicher Gesellschaften
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Article
Bestimmung der Trypsin- und Chymotrypsinaktivität im Stuhl. Eine sensible, spezifische Methode zum Nachweis der exokrinen Pankreasinsuffizienz
Der diagnostische Wert der Chymotrypsin-und Trypsinbestimmung im Stuhl (nachHaverback et al.) als neue Methode zur Erfassung der exokrinen Pankreasinsuffizienz wurde überprüft. Zur Objektivierung der exokrinen Pa...
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Elektronenmikroskopische Untersuchungen über das im Marklager lokalisierte Hirnödem
Das perifokale, durch intracerebrale Koagulationsnekrose beim Kanichen erzeugte Großhirnmarködem, ferner menschliches Marködemgewebe aus der Umgebung operierter Hirntumoren oder herdförmiger Hirnprozesse wurde...
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Bacillus Cereus Outgrowth “Early Proteins” and Their Possible Role in Control of Transcription
When dormant spores of Bacillus cereus are heat activated and then exposed to germination inducers, transcription is initiated and is followed by the synthesis of a small number of protein species (1). If, in add...
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Antigen-binding receptors on T cells from long-term MLR. Evidence of binding sites for allogeneic and self-MHC products
Antibody inhibition of radiolabelled stimulator membrane vesicle binding by T blasts activated in the mixed lymphocyte reaction (MLR) was used to identify responder-cell determinants involved in the binding ph...
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Organization and Replication of Pseudorabies Virus DNA
The genome of Pr virus, swine herpesvirus, consists of a linear, double-stranded DNA molecule, molecular weight approximately 90 × 106 (5, 21). Pr viral DNA has a relatively high G+C content (73 moles %) (2) and ...
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Ovarian development in 46,XY gonadal dysgenesis
In human the XY ovary is degenerative, there being scant evidence of persistence of that organ beyond the perinatal period. Here we describe indications of functional ovarian tissue in a 17-year-old female wit...
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Article
Mode of organization of lipid aggregates: A conformational analysis
A computational approach is used to predict the mode of organization of lipid molecules. The calculated aggregate states are fully compatible with the lipid phase preference: bilayers for dipalmitoylphosphatid...
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An Ia-positive mouse T-cell clone is functional in presenting antigen to other T cells
In this report we present data demonstrating the endogenous expression of I-region associated (la) antigens on a cloned line of mouse T cells, CTLL, as well as transcription of the invariant chain gene in thes...
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Characteristics of site variation among clones of the 340-base pair, tandemly repeated EcoR1 family of human DNA
Twenty-four clones of EcoR1-restricted, 340-base pair (bp) DNA derived from human DNA have been sequenced and compared to a published consensus sequence for this family. No two clones were found to have identical...
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Phospholipids as a possible instrument for translocation of nascent proteins across biological membranes
The interaction of phospholipids with precursor proteins, particularly with the mitochondrial precursor protein apocytochromec is reviewed and integrated with other aspects of protein insertion and translocation,...
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Restriction Fragment Length Polymorphism of HLA-DR7 Alleles and Association with HLA-B Antigens
Although HLA-DR7 appears to be serologically homo- 2. geneous (1), it may be split according to epitopes recognized by T cells (Dw7, Dwl1) and is normally found in association with either DQw2 or DQw3. This re...
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Identification of Dw2, Dw12, and “Short” DR2 Splits with Sequential Exon-Specific DRβ, DQβ, and DQα cDNA Probes
The HLA-DR2 specificity has been divided by alloantisera (DR2 and “short” DR2) and by T cells (Dw2, Dw12, DB9 (LD-5a), FJO, and LD-MN2). The FJO and LD-MN2 splits appear to correlate with the short DR2 serotyp...
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Haptoglobin DNA polymorphism in subterranean mole rats of the Spalax ehrenbergi superspecies in Israel
We analyzed the genetic diversity and environmental correlates of the haptoglobin (Hp) gene by RFLP analysis of 121 subterranean mole rats, comprising 13 populations belonging to the 4 chromosomal species (2n ...
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Apolipoprotein B amino acid 3611 substitution from arginine to glutamine creates the Ag (h/i) epitope: the polymorphism is not associated with differences in serum cholesterol and apolipoprotein B levels
A G-to A-DNA sequence change in exon 26 of the human apolipoprotein B (apo B) gene leads to a glutamine substitution for arginine at codon 3611 of the mature apolipoprotein B100 and causes a loss of an MspI site....
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Different haplotypes for cystic fibrosis-linked DNA polymorphisms in Polish and Dutch populations
We analyzed DNA from 34 Polish and 63 Dutch cystic fibrosis (CF) patients and their families using the polymorphic markers XV2c and KM19, which are in linkage disequilibrium with the CF mutation. Strong linkag...
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Prenatal diagnosis and linkage disequilibrium with cystic fibrosis for markers surrounding D7S8
Three polymorphic DNA markers surrounding the D7S8 locus were tested for their usefulness in the diagnosis of cystic fibrosis (CF) by linkage analysis. The markers correspond to the loci D7S424 and D7S426. The...
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Population genetics of the moss Plagiothecium undulatum (Hedw.) Schimp. I. Inheritance of allozymes
Twenty-one allozyme loci were assayed in a subpopulation of the dioecious moss Plagiothecium undulatum. Six loci were polymorphic and could be used to demonstrate the different expression of allozymes at the hapl...
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The recombination activating genes, RAG 1 and RAG 2, are on chromosome 11p in humans and chromosome 2p in mice
The recombination activating genes RAG-1 and RAG-2 are adjacent genes that act synergistically to activate variable-diversity-joining (V(D)J) recombination. Southern analysis of hybrid cell lines derived from pat...
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Gene dosage and down's syndrome: Metabolic and enzymatic changes in PC12 cells overexpressing transfected human liver-type phosphofructokinase
Down's syndrome (DS) is a human genetic disease caused by triplication of the distal third of chromosome 21 and overexpression of an unknown number of genes residing in it. The gene for the liver-type subunit ...