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    Article

    Impact of the introduction of EUCAST’s concept of “area of technical uncertainty”

    On the first of January 2019, the European Committee on Antimicrobial Susceptibility Testing, EUCAST, introduced the concept of “area of technical uncertainty” (ATU). The aim was to report on the incidence of ...

    Eveline Van Honacker, S. Vandendriessche in European Journal of Clinical Microbiology … (2022)

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    Article

    Efficient gene transfer in CLL by mRNA electroporation

    Chronic lymphocytic leukemia (CLL) consists of at least two major prognostic subgroups, characterized by different cellular and molecular markers. This observation sparked studies on the function and clinical ...

    F Van Bockstaele, V Pede, E Naessens, S Van Coppernolle, V Van Tendeloo in Leukemia (2008)

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    Article

    Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCRβ-HOXA rearrangement: a study of the Groupe Francophone de Cytogénétique Hématologique

    Recently, we and others described a new chromosomal rearrangement, that is, inv(7)(p15q34) and t(7;7)(p15;q34) involving the T-cell receptor beta (TCRβ) (7q34) and the HOXA gene locus (7p15) in 5% of T-cell acute...

    B Cauwelier, H Cavé, C Gervais, M Lessard, C Barin, C Perot, J Van den Akker in Leukemia (2007)

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    Article

    A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias

    Chromosomal translocations with breakpoints in T-cell receptor (TCR) genes are recurrent in T-cell malignancies. These translocations involve the TCRαδ gene (14q11), the TCRβ gene (7q34) and to a lesser extent th...

    F Speleman, B Cauwelier, N Dastugue, J Cools, B Verhasselt, B Poppe, N Van Roy in Leukemia (2005)