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  1. Article

    Open Access

    Nef interferes with development of thymic T cell precursors: differential mechanisms in HIV and SIV

    PJ Meuwissen, KK Ariën, I Vandewalle, E Naessens, H Vanderstraeten… in Retrovirology (2011)

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  2. No Access

    Article

    Efficient gene transfer in CLL by mRNA electroporation

    Chronic lymphocytic leukemia (CLL) consists of at least two major prognostic subgroups, characterized by different cellular and molecular markers. This observation sparked studies on the function and clinical ...

    F Van Bockstaele, V Pede, E Naessens, S Van Coppernolle, V Van Tendeloo… in Leukemia (2008)

  3. No Access

    Article

    Efficiency of transgenic T cell generation from gene-marked cultured human CD34+ cord blood cells is determined by their maturity and the cytokines present in the culture medium

    Success of gene therapy for diseases affecting the T cell lineage depends on the thymic repopulation by genetically engineered hematopoietic progenitor cells (HPC). Although it has been shown that retrovirally...

    B Verhasselt, E Naessens, M De Smedt, J Plum in Gene Therapy (2000)