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Article
Measuring what matters to older persons for active living: part I content development for the OPAL measure across four countries
Many older persons do not think of themselves as “patients” but as persons wishing to live as actively as possible for as long as possible. However, most health-related quality of life (HRQL) measures were dev...
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Article
Assessing the psychometric properties of quality of life measures in individuals with amyotrophic lateral sclerosis: a systematic review
Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease in adults. There are many patient-reported outcome measures (PROMs) for measuring quality of life (QoL) and health-related QoL (HRQoL...
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Article
Sex-stratified reference values for the life-space assessment in the Canadian longitudinal study on aging
The Life-Space Assessment (LSA) can compliment traditional physical performance measures of mobility by accounting for the interaction between individuals and their environment. However, there are no studies t...
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Article
Measuring physical performance in later life: reliability of protocol variations for common performance-based mobility tests
Performance-based tests of mobility or physical function such as the Timed Up and Go (TUG), gait speed, chair-rise, and single-leg stance (SLS) are often administered using different protocols in aging populat...
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Article
The impact of care–recipient relationship type on health-related quality of life in community-dwelling older adults with dementia and their informal caregivers
To assess whether there was an association between care–recipient relationship type and health-related quality of life (HRQL) of older persons living with dementia (PLWD) and their informal caregivers, and whe...
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Article
Reducing research wastage by starting off on the right foot: optimally framing the research question
Strongly framed research questions are clear as to the population (P), the exposures or interventions (E/I), comparison groups (C), outcomes (O), time when relevant (T), and what the investigator wants to know...
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Article
Open AccessCommunity-based group physical activity and/or nutrition interventions to promote mobility in older adults: an umbrella review
Physical activity and a healthy diet are important in hel** to maintain mobility with aging. This umbrella review aims to identify group-based physical activity and/or nutrition interventions for community-d...
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Article
Transforming challenges into opportunities: conducting health preference research during the COVID-19 pandemic and beyond
The disruptions to health research during the COVID-19 pandemic are being recognized globally, and there is a growing need for understanding the pandemic’s impact on the health and health preferences of patien...
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Article
Open AccessContent validity of preference-based measures for economic evaluation in chronic obstructive pulmonary disease
Generic preference-based measures (GPBMs) are health-related quality of life (HRQoL) measures commonly used to evaluate the cost-utility of interventions in healthcare. However, the degree to which the content...
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Article
Open AccessAn international mixed methods study to develop a new preference-based measure for women with breast cancer: the BREAST-Q Utility module
Generic preference-based measures (PBM), though commonly used, may not be optimal for use in economic evaluations of breast cancer interventions. No breast cancer-specific PBM currently exists, and the generic...
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Article
Measurement properties of preference-based measures for economic evaluation in COPD: a systematic review
Preference-based measures can provide measurements of health-related quality of life and be utilized for cost-effectiveness analyses of interventions in individuals with chronic obstructive pulmonary disease (...
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Article
Open AccessDevelopment and validation of an algorithm to assess risk of first-time falling among home care clients
The falls literature focuses on individuals with previous falls, so little is known about individuals who have not experienced a fall in the past. Predicting falls in those without a prior event is critical fo...
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Article
In support of an individualized approach to assessing quality of life: comparison between Patient Generated Index and standardized measures across four health conditions
Individualized measures of health-related quality life (HRQL) have been used for decades and shown to provide unique information, but little work has been done to explain this uniqueness particularly across he...
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Article
Contribution of symptom clusters to multiple sclerosis consequences
There were two objectives in this study: (1) to identify, among women and men with MS, the extent to which different MS-related symptoms, including fatigue, pain, sleep disturbance, depression, anxiety, irrita...
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Article
A Review of the Psychometric Properties of Generic Utility Measures in Multiple Sclerosis
The reliability and validity of generic utility measures have not yet been summarized in people with multiple sclerosis (MS). It is important to assess the psychometric properties of these measures, to ensure ...
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Article
Using existing data to identify candidate items for a health state classification system in multiple sclerosis
In multiple sclerosis (MS), the use of preference-based measures is limited to generic measures such as Health Utilities Index Mark 2 and 3, the EQ-5D and the SF-6D. However, the challenge of using such generi...
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Article
Open AccessDo generic utility measures capture what is important to the quality of life of people with multiple sclerosis?
The three most widely used utility measures are the Health Utilities Index Mark 2 and 3 (HUI2 and HUI3), the EuroQol-5D (EQ-5D) and the Short-Form-6D (SF-6D). In line with guidelines for economic evaluation fr...
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Article
Erratum to: Using latent trajectory analysis of residuals to detect response shift in general health among patients with multiple sclerosis
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Article
Using latent trajectory analysis of residuals to detect response shift in general health among patients with multiple sclerosis article
Individuals experiencing a change in health may experience a response shift that may attenuate HRQoL change estimates. The objective of this study was to estimate the proportion of individuals with multiple sc...