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Article
Cell-cell and cell-matrix adhesion molecules in human heart and lung transplants
The interaction of immune cells with endothelial and target cells and extracellular matrix in human organ transplants is regulated by a number of receptor-ligand molecules. The molecules mediating intercellula...
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Chapter
Engineering of a miniature 3-D hepatic cell plate culture model
The development of primary liver cell culture techniques has a long standing history that has contributed significantly to our current knowledge about the relevance of individual aspects of the hepatic microen...
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Article
Diazepam metabolism and albumin secretion of porcine hepatocytes in collagen-sandwich after cryopreservation
Cryopreserved porcine hepatocytes in collagen cultures secreted albumin (up to 98 ± 3 μg ml−1; non-cryopreserved controls: 100 ± 9 μg ml−1) and metabolised diazepam (67.5% ± 7.5% of initially applied diazepam are...
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Article
Scalable expansion of human pluripotent stem cells in suspension culture
Routine commercial and clinical applications of human pluripotent stem cells (hPSCs) and their progenies will require increasing cell quantities that cannot be provided by conventional adherent culture technol...
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Reference Work Entry In depth
Decellularized Vascular Grafts
Cardiovascular disease is one of the main causes of mortality and morbidity worldwide. The “gold standard” for the replacement/repair of diseased blood vessels is substitution with autologous vessels. However,...
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Article
Open AccessMatched comparison of decellularized homografts and bovine jugular vein conduits for pulmonary valve replacement in congenital heart disease
For decades, bovine jugular vein conduits (BJV) and classic cryopreserved homografts have been the two most widely used options for pulmonary valve replacement (PVR) in congenital heart disease. More recently,...