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Article
Open AccessExploring the effects of fitbit incentive on treatment outcomes in veterans undergoing intensive pain rehabilitation program
This study compares clinical pain outcomes between patients in a pain treatment program that received a Fitbit, to patients that did not. We also explored: (1) cognitive, emotional, and psychological factors t...
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Article
State-specific alterations in the neural computations underlying inhibitory control in women remitted from bulimia nervosa
The neurocomputational processes underlying bulimia nervosa and its primary symptoms, out-of-control overeating and purging, are poorly understood. Research suggests that the brains of healthy individuals form...
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Article
Open AccessUnsupervised learning for prognostic validity in patients with chronic pain in transdisciplinary pain care
Chronic pain is not a singular disorder and presents in various forms and phenotypes. Here we show data from a cohort of patients seeking treatment in a transdisciplinary pain clinic. Patients completed a mult...
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Article
Correction to: Deriving psychiatric symptom-based biomarkers from multivariate relationships between psychophysiological and biochemical measures
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Article
Open AccessHIV peripheral neuropathy‐related degeneration of white matter tracts to sensorimotor cortex
Human immunodeficiency virus-associated distal sensory polyneuropathy (HIV-DSP) affects up to 50% of people with HIV and is associated with depression, unemployment, and generally worsened quality of life. Pre...
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Article
Deriving psychiatric symptom-based biomarkers from multivariate relationships between psychophysiological and biochemical measures
Identification of biomarkers for psychiatric disorders remains very challenging due to substantial symptom heterogeneity and diagnostic comorbidity, limiting the ability to map symptoms to underlying neurobiol...
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Article
Open AccessChanges in cognitive and behavioral control after lamotrigine and intensive dialectical behavioral therapy for severe, multi-impulsive bulimia nervosa: an fMRI case study
Adults with bulimia nervosa (BN) and co-occurring emotional dysregulation and multiple impulsive behaviors are less responsive to existing interventions. Initial data suggest that the combination of Dialectica...
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Article
The effect of obstructed action efficacy on reward-based decision-making in healthy adolescents: a novel functional MRI task to assay frustration
Frustration is common in adolescence and often interferes with executive functioning, particularly reward-based decision-making, and yet very little is known about how incidental frustrating events (independen...
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Article
The effects of FAAH inhibition on the neural basis of anxiety-related processing in healthy male subjects: a randomized clinical trial
Acute pharmacological inhibition of the anandamide-degrading enzyme, fatty acid amide hydrolase (FAAH), prolongs the regulatory effects of endocannabinoids and reverses the stress-induced anxiety state in a ca...
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Article
Proactive engagement of cognitive control modulates implicit approach-avoidance bias
Implicit social-affective biases—reflected in a propensity to approach positive and avoid negative stimuli—have been documented in humans with paradigms, such as the Approach-Avoidance Task (AAT). However, the...
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Article
Evidence for a novel subcortical mechanism for posterior cingulate cortex atrophy in HIV peripheral neuropathy
We previously reported that neuropathic pain was associated with smaller posterior cingulate cortical (PCC) volumes, suggesting that a smaller/dysfunctional PCC may contribute to development of pain via impair...
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Article
Open AccessIncreased anticipatory brain response to pleasant touch in women remitted from bulimia nervosa
Bulimia nervosa (BN) is characterized by affective instability and dysregulated behaviors (binge eating, fasting, self-induced vomiting) that disrupt bodily homeostasis. Mechanisms underlying dysregulation in ...
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Article
Altered anticipation and processing of aversive interoceptive experience among women remitted from bulimia nervosa
Bulimia nervosa (BN) is characterized by dysregulated intake of food, which may indicate homeostatic imbalance. Critically important for homeostatic regulation is interoception, or the sensing and processing o...
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Article
Open AccessNeural hypersensitivity to pleasant touch in women remitted from anorexia nervosa
Interoception, or the sensing and integration of bodily state signals, has been implicated in anorexia nervosa (AN), given that the hallmark symptoms involve food restriction and body image disturbance. Here w...
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Article
Earlier alcohol use onset prospectively predicts changes in functional connectivity
Half of all new alcohol initiates are between 12 and 17 years old. This is a period of intense neurodevelopment, including changes in functional connectivity patterns among higher-order function areas. It is c...
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Chapter
Emerging Approaches to Neurocircuits in PTSD and TBI: Imaging the Interplay of Neural and Emotional Trauma
Posttraumatic stress disorder (PTSD) and traumatic brain injury (TBI) commonly co-occur in general and military populations and have a number of overlap** symptoms. While research suggests that TBI is risk f...
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Chapter
The Future of Contextual Fear Learning for PTSD Research: A Methodological Review of Neuroimaging Studies
There has been a great deal of recent interest in human models of contextual fear learning, particularly due to the use of such paradigms for investigating neural mechanisms related to the etiology of posttrau...
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Article
Inflexible Functional Connectivity of the Dorsal Anterior Cingulate Cortex in Adolescent Major Depressive Disorder
Recent evidence suggests that anterior cingulate cortex (ACC) maturation during adolescence contributes to or underlies the development of major depressive disorder (MDD) during this sensitive period. The ACC ...
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Article
Large-Scale Hypoconnectivity Between Resting-State Functional Networks in Unmedicated Adolescent Major Depressive Disorder
Major depressive disorder (MDD) often emerges during adolescence, a critical period of brain development. Recent resting-state fMRI studies of adults suggest that MDD is associated with abnormalities within an...
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Article
Open AccessAltered amygdala activation during face processing in Iraqi and Afghanistani war veterans
Exposure to combat can have a significant impact across a wide array of domains, and may manifest as post-traumatic stress disorder (PTSD), a debilitating mental illness that is associated with neural and affe...
