22 Result(s)
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Lindsay M. Squeglia
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Article
Sex and Gender Differences in Simultaneous Alcohol and Cannabis Use: a Narrative Review
The aim is to review recent literature on sex and gender differences in patterns of use, motives, pharmacological effects, and consequences of simultaneous alcohol and cannabis use (SAC).
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Article
N-acetylcysteine does not alter neurometabolite levels in non-treatment seeking adolescents who use alcohol heavily: A preliminary randomized clinical trial
Current treatments for adolescent alcohol use disorder (AUD) are mainly psychosocial and limited in their efficacy. As such, pharmacotherapies are being investigated as potential adjunctive treatments to bolst...
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Article
Adolescent Neurodevelopment Within the Context of Impulsivity and Substance Use
The aim of the present review is to provide an update on recent studies examining adolescent neurodevelopment in the context of impulsivity and substance use. We provide a review of the neurodevelopmental chan...
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Treatment of Adolescents
Adolescence is a critical phase of psychosocial and neural development that oftentimes overlaps with the initation and escalation of substance use, particularly alcohol use. Adolescent alcohol use is not innoc...
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Article
Brain metabolite alterations related to alcohol use: a meta-analysis of proton magnetic resonance spectroscopy studies
Alcohol misuse and alcohol use disorder (AlUD) have neurobiological consequences. This meta-analysis of proton magnetic resonance spectroscopy (MRS) studies aimed to assess the differences in brain metabolite ...
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Article
Neural vulnerability and hurricane-related media are associated with post-traumatic stress in youth
The human toll of disasters extends beyond death, injury and loss. Post-traumatic stress (PTS) can be common among directly exposed individuals, and children are particularly vulnerable. Even children far remo...
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Article
Open AccessScreen media activity does not displace other recreational activities among 9–10 year-old youth: a cross-sectional ABCD study®
Screen media is among the most common recreational activities engaged in by children. The displacement hypothesis predicts that increased time spent on screen media activity (SMA) may be at the expense of enga...
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Depressive symptoms and cannabis use in a placebo-controlled trial of N-Acetylcysteine for adult cannabis use disorder
Depression is common among individuals with cannabis use disorder (CUD), particularly individuals who present to CUD treatment. Treatments that consider this comorbidity are essential.
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Unconscious Bias and the Diagnosis of Disruptive Behavior Disorders and ADHD in African American and Hispanic Youth
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Article
Behavioral Treatments for Adolescent Cannabis Use Disorder: a Rationale for Cognitive Retraining
Adolescent cannabis use represents a significant public health concern. Cannabis experimentation typically begins in adolescence and increases the odds of meeting criteria for cannabis use disorder. Cannabis u...
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Measuring Within-Individual Cannabis Reduction in Clinical Trials: a Review of the Methodological Challenges
Cannabis abstinence, traditionally, is the primary outcome in cannabis use disorder (CUD) treatment trials. Due to the changing legality of cannabis, patient goals, and preliminary evidence suggesting that ind...
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Article
Race, Ethnicity, and Culture in the Medical Record: Implicit Bias or Patient Advocacy?
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Article
Adolescent Substance Use Disorder Treatment: an Update on Evidence-Based Strategies
To examine the most recent published evidence (2016–2019) regarding the treatment of adolescent substance use disorders and to provide an update on evidence-based strategies, adjunctive interventions, and meth...
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Article
Neurobiological and Cognitive Profile of Young Binge Drinkers: a Systematic Review and Meta-Analysis
This review provides the first systematic and quantitative synthesis of the literature examining the relationship between binge drinking, cognition, brain structure and function in youth aged 10 to 24 years. P...
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Prospective changes in neural alcohol cue reactivity in at-risk adolescents
Adolescence represents an ideal time for elucidating the etiology of cue reactivity profiles. This study examined the influence of three risk factors consistently associated with heavy adolescent drinking on a...
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Article
Earlier alcohol use onset prospectively predicts changes in functional connectivity
Half of all new alcohol initiates are between 12 and 17 years old. This is a period of intense neurodevelopment, including changes in functional connectivity patterns among higher-order function areas. It is c...
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Changes in marijuana use symptoms and emotional functioning over 28-days of monitored abstinence in adolescent marijuana users
Advancing marijuana prevention and intervention efforts are important given the decreasing perception of harm among adolescents and increasing marijuana legalization.
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Article
Alcohol consumption as a predictor of reactivity to smoking and stress cues presented in the natural environment of smokers
The high prevalence of co-occurring alcohol and tobacco use underscores the importance of understanding the influence of alcohol consumption on risk factors for smoking and relapse. Alcohol has been shown to i...
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Alcohol and Drug Use and the Develo** Brain
Adolescence is an important neurodevelopmental period marked by rapidly escalating rates of alcohol and drug use. Over the past decade, research has attempted to disentangle pre- and post-substance use effects...
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Structural connectivity of neural reward networks in youth at risk for substance use disorders
Having a positive family history of alcohol use disorders (FHP), as well as aberrant reward circuitry, has been implicated in the initiation of substance use during adolescence. This study explored the relatio...
