38 Result(s)

Article

Defining the biogeographical map and potential bacterial translocation of microbiome in human ‘surface organs’

The microbiome in a specific human organ has been well-studied, but few reports have investigated the multi-organ microbiome as a whole. Here, we aim to analyse the intra-individual inter-organ and intra-organ...

Jun-Jun She, Wei-**n Liu, **ao-Ming Ding, Gang Guo, **g Han… in Nature Communications (2024)

Article

A deep unrolled neural network for real-time MRI-guided brain intervention

Accurate navigation and targeting are critical for neurological interventions including biopsy and deep brain stimulation. Real-time image guidance further improves surgical planning and MRI is ideally suited ...

Zhao He, Ya-Nan Zhu, Yu Chen, Yi Chen, Yuchen He, Yuhao Sun… in Nature Communications (2023)

Article

Common evolutionary trajectory of short life-cycle in Brassicaceae ruderal weeds

Weed species are detrimental to crop yield. An understanding of how weeds originate and adapt to field environments is needed for successful crop management and reduction of herbicide use. Although early flowe...

Ling-Zi Li, Zhou-Geng Xu, Tian-Gen Chang, Long Wang, Heng Kang… in Nature Communications (2023)

Article

Comparison of pedicle screw fixation with or without cement augmentation for treating single-segment isthmic spondylolisthesis in the osteoporotic spine

The present study examined the necessity of cement-augmented pedicle screw fixation in osteoporotic patients with single-segment isthmic spondylolisthesis.Fifty-nine cases were reviewed retrospectively. Thirty...

Jian-cheng Peng, Hui-zhi Guo, Chen-guang Zhan, Hua-sheng Huang… in Scientific Reports (2023)

Article

Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles

Chiral heterocyclic compounds are needed for important medicinal applications. We report an in silico strategy for the biocatalytic synthesis of chiral N- and O-heterocycles via Baldwin cyclization modes of hydro...

Jun-Kuan Li, Ge Qu, Xu Li, Yuchen Tian, Chengsen Cui… in Nature Communications (2022)

Article

Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP

The emergence of methicillin-resistant Staphylococcus aureus isolates highlights the urgent need to develop more antibiotics. ClpP is a highly conserved protease regulated by ATPases in bacteria and in mitochondr...

Bingyan Wei, Tao Zhang, Pengyu Wang, Yihui Pan, Jiahui Li… in Nature Communications (2022)

Article

Tandem utilization of CO₂ photoreduction products for the carbonylation of aryl iodides

Photocatalytic CO₂ reduction reaction has been developed as an effective strategy to convert CO₂ into reusable chemicals. However, the reduction products of this reaction are often of low utilization value. Herei...

Yuan-Sheng **a, Meizhong Tang, Lei Zhang, Jiang Liu, Cheng Jiang… in Nature Communications (2022)

Article

Comparison of CT findings and histopathological characteristics of pulmonary cryptococcosis in immunocompetent and immunocompromised patients

Pulmonary cryptococcosis (PC) is a common fungal infectious disease, and infection can occur in patients with any immune function. To better understand PC, we compared the CT findings and histopathological res...

Dong-xu Wang, Qing Zhang, Qiu-ting Wen, Guo-xu Ding, Yu-guang Wang… in Scientific Reports (2022)

Article

Presynaptic NMDARs on spinal nociceptor terminals state-dependently modulate synaptic transmission and pain

Postsynaptic NMDARs at spinal synapses are required for postsynaptic long-term potentiation and chronic pain. However, how presynaptic NMDARs (PreNMDARs) in spinal nociceptor terminals control presynaptic plas...

Rou-Gang **e, Wen-Guang Chu, Da-Lu Liu, Xu Wang, Sui-Bin Ma… in Nature Communications (2022)

Article

Estradiol-induced inhibition of endoplasmic reticulum stress normalizes splenic CD4 + T lymphocytes following hemorrhagic shock

The aim is to investigate that 17β-estradiol (E2)/estrogen receptors (ERs) activation normalizes splenic CD4 + T lymphocytes proliferation and cytokine production through inhibition of endoplasmic reticulum st...

Peng Wang, Li-Na Jiang, Chen Wang, Ying Li, Meng Yin, Hui-Bo Du… in Scientific Reports (2021)

Article

Addendum: A pneumonia outbreak associated with a new coronavirus of probable bat origin

Peng Zhou, **ng-Lou Yang, **an-Guang Wang, Ben Hu, Lei Zhang, Wei Zhang… in Nature (2020)

Article

A novel nomogram predicting the risk of positive biopsy for patients in the diagnostic gray area of prostate cancer

The roles played by several inflammatory factors in screening for prostate cancer (PCa) among gray area patients, namely those with serum prostate-specific antigen (PSA) levels between 4 and 10 ng/ml, have not...

Guang-Dong Hou, Yu Zheng, Wan-**ang Zheng, Ming Gao, Lei Zhang… in Scientific Reports (2020)

Article

The Litsea genome and the evolution of the laurel family

The laurel family within the Magnoliids has attracted attentions owing to its scents, variable inflorescences, and controversial phylogenetic position. Here, we present a chromosome-level assembly of the Litsea c...

Yi-Cun Chen, Zhen Li, Yun-**ao Zhao, Ming Gao, Jie-Yu Wang… in Nature Communications (2020)

Article

A pneumonia outbreak associated with a new coronavirus of probable bat origin

Since the outbreak of severe acute respiratory syndrome (SARS) 18 years ago, a large number of SARS-related coronaviruses (SARSr-CoVs) have been discovered in their natural reservoir host, bats^1–4. Previous studi...

Peng Zhou, **ng-Lou Yang, **an-Guang Wang, Ben Hu, Lei Zhang, Wei Zhang… in Nature (2020)

Article

Genome-wide analysis of Cushion willow provides insights into alpine plant divergence in a biodiversity hotspot

The Hengduan Mountains (HDM) biodiversity hotspot exhibits exceptional alpine plant diversity. Here, we investigate factors driving intraspecific divergence within a HDM alpine species Salix brachista (Cushion wi...

Jia-hui Chen, Yuan Huang, Benjamin Brachi, Quan-zheng Yun… in Nature Communications (2019)

Article

Targeting 17q23 amplicon to overcome the resistance to anti-HER2 therapy in HER2+ breast cancer

Chromosome 17q23 amplification occurs in ~11% of human breast cancers. Enriched in HER2+ breast cancers, the 17q23 amplification is significantly correlated with poor clinical outcomes. In addition to the prev...

Yunhua Liu, Jiangsheng Xu, Hyun Ho Choi, Cecil Han, Yuanzhang Fang… in Nature Communications (2018)

Article

Identifying long-term stable refugia for relict plant species in East Asia

Today East Asia harbors many “relict” plant species whose ranges were much larger during the Paleogene-Neogene and earlier. The ecological and climatic conditions suitable for these relict species have not bee...

Cindy Q. Tang, Tetsuya Matsui, Haruka Ohashi, Yi-Fei Dong… in Nature Communications (2018)

Article

Isolation, Structure Elucidation, and Absolute Configuration of Germacrane Isomers from Carpesium divaricatum

Five sets of germacrane isomers (1/8/17, 2/7/10/11/13/16/18, 3/4/5/14/20, 6/12/15, and 9/19) with different skeletal types, including seven new ones (1–3, 8–9, and 15–16) were isolated from the whole plant of Car...

Tao Zhang, Jia-Huan Chen, **-Guang Si, Gang Ding, Qiu-Bo Zhang… in Scientific Reports (2018)

Article

PEDOT:PSS/graphene quantum dots films with enhanced thermoelectric properties via strong interfacial interaction and phase separation

The typical conductive polymer of PEDOT:PSS has recently attracted intensive attention in thermoelectric conversion because of its low cost and low thermal conductivity as well as high electrical conductivity....

Fei-Peng Du, Nan-Nan Cao, Yun-Fei Zhang, ** Fu, Yan-Guang Wu… in Scientific Reports (2018)

Article

Preoperative Heart Rate Variability as Predictors of Vagus Nerve Stimulation Outcome in Patients with Drug-resistant Epilepsy

Vagus nerve stimulation (VNS) is an adjunctive treatment for drug-resistant epilepsy (DRE). However, it is still difficult to predict which patients will respond to VNS treatment and to what extent. We aim to ...

Hong-Yun Liu, Zhao Yang, Fan-Gang Meng, Yu-Guang Guan, Yan-Shan Ma… in Scientific Reports (2018)