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Article
Open AccessIsolation, Structure Elucidation, and Absolute Configuration of Germacrane Isomers from Carpesium divaricatum
Five sets of germacrane isomers (1/8/17, 2/7/10/11/13/16/18, 3/4/5/14/20, 6/12/15, and 9/19) with different skeletal types, including seven new ones (1–3, 8–9, and 15–16) were isolated from the whole plant of Car...
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Article
Molecular epigenetic approach activates silent gene cluster producing dimeric bis-spiro-azaphilones in Chaetomium globosum CBS148.51
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Article
Bmi1 combines with oncogenic KRAS to induce malignant transformation of human pancreatic duct cells in vitro
It is critical to understand the pathogenesis of preinvasive stages of pancreatic duct adenocarcinoma (PDAC) for develo** novel potential diagnostic and therapeutic targets. The polycomb group family member ...
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Article
Open AccessNew Highly Oxygenated Germacranolides from Carpesium divaricatum and their Cytotoxic Activity
Eight highly oxygenated germacranolides (1–8) including four new ones (2–5) were isolated from the whole plant of Carpesium divaricatum. The planar structures and relative configurations of the new compounds were...