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4,715 Result(s)
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Chapter
Toxicity Studies of Exosomes and Potential Overcome Approaches
Exosomes are nanosized, tiny extracellular particles that are produced by cells. They include varying quantities of protein, mRNA, miRNA, DNA, and lipids, along with various other bioactive chemicals to perfor...
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Role of Vitamin B12 in Cardiovascular Disease
(CVD) is a concern worldwide. Different vitamins are considered important for maintaining cardiovascular function in health . has been linked to an increase in risk of CVD as well as elevated homocyste...
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Mechanistic Effects of Vitamin B6 and B12 on Inflammation and Cancer
The relationship , and cancer is complex. Healthy eating can boost the immune system and reduce cancer risk, but both inadequate and excessive nutrition can lead to inflammation are crucial for overall he...
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The Cardio-protective Effect of Water-Soluble Vitamins on Anticancer Drug-Induced Cardiotoxicity
Cancer is one of the many consequences of chemotherapies, agents, and radiation therapy used to . Many studies have implicated that the onset of cardiotoxicity can have drastic effects on that can /con...
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The Role of Folic Acid in the Regulation of Homocysteine Levels and Cardiovascular Disease
is a crucial B-vitamin that plays a significant role in by effectively levels. Elevated homocysteine levels have been consistently associated with an increased risk and facilitate the conversion of ...
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Antiatherogenic Effects of Vitamins, Mediterranean Diet and DASH Diet: An Overview for the Prevention of Cardiovascular Diseases
is the progressive pathologic phenomenon where the arterial blood vessels become hard and narrow, consequently restricting blood flow to the vital organs and tissues. Atherogenesis has been reported to be the...
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The Role of Vitamin C in the Prevention and Treatment of Cancers
is a water-soluble vitamin, and is contained in many vegetables, fruits and other foods. Vitamin C possesses many bioactivities, such shows anticancer action against , such as colorectal cancer, breast...
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Discovering the Potential of Bee Bread from Malaysian Stingless Bee as Vitamins B1, B3, and B6-Rich Source for Health and Disease
The application of alternative medicine products has grown substantially over the past few decades, and it is projected that almost 80% of patients worldwide rely on them for a certain aspect of their primary ...
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Natural and Plant-Derived Vitamins: A Comprehensive Review of Biochemistry, Pharmacology and Nutritional Benefits in Health and Disease
In this comprehensive review, we reflect of the historical perspectives in the discovery of vitamins about a century ago and summarize the neuroprotective, cardioprotective, and . We also focus on the clinica...
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Exosomes: Biogenesis, Composition, and Synthesis
Exosomes are tiny, membrane-bound vesicles that are present in many body fluids and perform important functions in cell-to-cell communication. The creation of early endosomes that develop into multivesicular b...
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The Interplay of Thiamine and Cardiovascular Diseases
is a water-soluble vitamin that performs a crucial role in a wide range of physiological processes in the body, which cater to of glucose, amino acids, and the synthesis of nucleic acid and lipids. Given th...
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Role of Exosomes in Multiple Sclerosis
Multiple sclerosis (MS) is a central nervous system (CNS) autoimmune disease in which autoreactive immune cells recognize myelin antigens and cause demyelination and axonal damage. Inflammatory CD4+ T cells that ...
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Role of Exosomes in Parkinson’s and Alzheimer’s Diseases
Parkinson’s disease (PD), the second most common neurological ailment in the world after Alzheimer’s disease (AD), affects about 1% of those over 65 years. Exosomes were first thought to be useless cell debris...
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Role of Exosomes in Management of Depression
Depression or major depressive disorder (MDD) is a disease that is characterized by prolonged sad mood. In most of the cases, the disorder is presented with other comorbid illnesses such as anxiety, Alzheimer’...
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Advancement of Engineered Exosomes to Deliver Therapeutic Protein Cargos in Brain Disorders
The potential use of exosomes as biomarkers for central nervous system disorders is an intriguing idea because they can monitor disease development, enable early diagnosis, and optimize treatment outcomes. Exo...
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Recent Challenges of Exosomes as a Novel Carrier in Various Brain Disorders
Exosome application has recently gained significant attention as a promising area of nanotechnology research for the development of drugs and diagnostic tools for a wide range of disorders. Due to their inhere...
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Exosomes as a Future Diagnostic Tool for Brain Disorders
The brain is a highly complex interconnected neuronal network with a specialized blood–brain barrier (BBB). The BBB is a diffusion barrier crucial for protecting normal brain function by blocking dangerous com...
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Vitamin B7 (Biotin) and Its Role in Hair, Skin and Nail Health
This chapter comprehensively explores biotin, a , and its multifaceted impact on human health, particularly promoting of hair, skin, and nails. It begins by explaining how to recognize and its unmistakabl...
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Association of Vitamin B12 with Bone Mineral Density
is a global ongoing issue resulting in rate. The associated morbidity and mortality with these fractures results in economic burden. The dietary habits play an important role of osteoporosis. It is an est...
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The Interweaving of B9- and B12-Dependent Reactions and Their Clinical Implications
) and vitamin ) are part of pathways. Both of them are water-soluble compounds and play an essential role in DNA production, amino acid activities regulation. These vitamins are involved in very few r...