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Chapter
Mitigation of Dementia and Alzheimer’s Disease with Lipophilic Vitamins and Their Derivatives: Preclinical and Clinical Evidence
Recent research has been exploring the link between vitamin deficiencies and the pathogenesis of neurodegenerative ailments such as cognition impairment, dementia, and Alzheimer’s disease (AD). Lipophilic vita...
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Chapter
Antiatherogenic Effects of Vitamins, Mediterranean Diet and DASH Diet: An Overview for the Prevention of Cardiovascular Diseases
is the progressive pathologic phenomenon where the arterial blood vessels become hard and narrow, consequently restricting blood flow to the vital organs and tissues. Atherogenesis has been reported to be the...
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Chapter
Natural and Plant-Derived Vitamins: A Comprehensive Review of Biochemistry, Pharmacology and Nutritional Benefits in Health and Disease
In this comprehensive review, we reflect of the historical perspectives in the discovery of vitamins about a century ago and summarize the neuroprotective, cardioprotective, and . We also focus on the clinica...
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Chapter
The Protective Role of Vitamins in Skincare and Cosmeceutical Products: Mechanisms Involved to Re-engineer the Skin Towards a Healthy State
There is overwhelming evidence from in vitro and in vivo investigations as well as animal and human studies that incorporation of some vitamins promote healthy skin and re-engineer the skin to a healthy st...
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Article
Challenges and Opportunities of Metal Chelation Therapy in Trace Metals Overload-Induced Alzheimer’s Disease
Essential trace metals like zinc (Zn), iron (Fe), and copper (Cu) play an important physiological role in the metabolomics and healthy functioning of body organs, including the brain. However, abnormal accumul...
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Chapter
Quercetin: A Promising Flavonoid for the Therapy of Cardiac Hypertrophy and Heart Failure Mediated by the Renin Angiotensin System
(RAS) plays an essential role in regulating levels in the body and maintaining cardiovascular homeostasis. However, overactivation of RAS leads to and cardiac overload, especially in the , causing . As ...
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Chapter
Role of Renin Angiotensin System in the Pathophysiology of Coronary Heart Disease: Advancements in Diagnosis, Therapy and Preventive Strategies
The incidence of (CHD) has been escalating over the years, and epidemiological data suggests that CHD causes nearly 17.9 million deaths worldwide annually. Myocardial infarction and stroke resulting from CHD...
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Article
Open AccessPhysical activity induced alterations of gut microbiota in humans: a systematic review
Gut microbiota is considered to have a great impact on human health and disease. While it is widely recognized that the gut microbiota of healthy individuals differs from those with obesity, inflammatory bowel...
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Chapter
The Importance of Drug Dose Adjustment in Elderly Patients with Special Considerations for Patients on Diverse Co-medications and Antidepressants
The geriatric population is escalating globally, and the need for treating infectious and non-infectious diseases in elderly patients is also correspondingly increasing worldwide. In clinical trials and under ...
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Chapter
Pathophysiology of Obesity-Related Non-communicable Chronic Diseases and Advancements in Preventive Strategies
is characterized by an excessive accumulation of (WAT) causing increases in and (BMI >30 kg/m2). WAT stores energy and releases free fatty acids, but it is also a dynamic that triggers the production o...
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Chapter
Potentials of Phytopharmaceuticals for Treating Microbiological and Oxidative Stress-Induced Type 2 Diabetes
Currently, type 2 diabetes is one of the most widespread noncommunicable maladies that inflict more than 400 million people globally. Diabetes-induced oxidative stress and distortion in gastrointestinal microb...
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Chapter
An overview of the influence of ACE inhibitors on fetal-placental circulation and perinatal development
The renin-angiotensin system is associated with a variety of pathophysiological processes in many organ systems, and is known to be involved in the normal regulation of blood pressure and in the pathogenesis o...
