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    Article

    Evaluating the Use of Immersive Interactive Mixed Reality (I2MR) Technology in Special Needs Education in Singapore

    The use of immersive interactive mixed reality (I2MR) technologies has been of interest to educators due to the rapid advancement of technology, lowered cost, and increased engagement of the senses. This is parti...

    Shawn Zheng Kai Tan, Maria Shendyapina in Technology, Knowledge and Learning (2024)

  2. Article

    Open Access

    Author Correction: Brain Data Standards - A method for building data-driven cell-type ontologies

    Shawn Zheng Kai Tan, Huseyin Kir, Brian D. Aevermann, Tom Gillespie in Scientific Data (2023)

  3. Article

    Open Access

    Brain Data Standards - A method for building data-driven cell-type ontologies

    Large-scale single-cell ‘omics profiling is being used to define a complete catalogue of brain cell types, something that traditional methods struggle with due to the diversity and complexity of the brain. But...

    Shawn Zheng Kai Tan, Huseyin Kir, Brian D. Aevermann, Tom Gillespie in Scientific Data (2023)

  4. Article

    Prelimbic Cortical Stimulation Improves Spatial Memory Through Distinct Patterns of Hippocampal Gene Expression in Aged Rats

    Dementia poses major health challenges worldwide, yet current treatments are faced with issues of efficacy and toxicity. Deep brain stimulation (DBS) is a promising non-pharmacological treatment for dementia, ...

    Shawn Zheng Kai Tan, Joveen Neoh, Andrew John Lawrence, Ed Xuekui Wu in Neurotherapeutics (2020)

  5. Article

    Open Access

    A practical approach to the ethical use of memory modulating technologies

    Recent advancements in neuroscientific techniques have allowed us to make huge progress in our understanding of memories, and in turn has paved the way for new memory modification technologies (MMTs) that can ...

    Shawn Zheng Kai Tan, Lee Wei Lim in BMC Medical Ethics (2020)

  6. No Access

    Article

    Serotonergic treatment normalizes midbrain dopaminergic neuron increase after periaqueductal gray stimulation

    Electrical stimulation of the dorsolateral periaqueductal gray (dlPAG) in rats has been shown to elicit panic-like behaviour and can be a useful as an unconditioned stimulus for modelling anticipatory fear and...

    Shawn Zheng Kai Tan, Yasin Temel, Ariel Yovela Chan in Brain Structure and Function (2020)

  7. Article

    Open Access

    Immunohistochemical insights into Saffold virus infection of the brain of juvenile AG129 mice

    Saffold Virus (SAFV) is a human cardiovirus that is suspected of causing infection of the central nervous system (CNS) in children. While recent animal studies have started to elucidate the pathogenesis of SAF...

    Shawn Zheng Kai Tan, Mookkan Prabakaran in Virology Journal (2016)

  8. Article

    Open Access

    Tetratricopeptide repeat domain 9A modulates anxiety-like behavior in female mice

    Tetratricopeptide repeat domain 9A (TTC9A) expression is abundantly expressed in the brain. Previous studies in TTC9A knockout (TTC9A−/−) mice have indicated that TTC9A negatively regulates the action of estrogen...

    Lee Wei Lim, Smeeta Shrestha, Yu Zuan Or, Shawn Zheng Kai Tan in Scientific Reports (2016)

  9. No Access

    Article

    Spatial Learning Requires mGlu5 Signalling in the Dorsal Hippocampus

    We examined the role of hippocampal metabotropic glutamate receptor 5 (mGlu5) in spatial learning and memory. Although it has been shown that mGlu5 signalling is required for certain forms of learning and memo...

    Shawn Zheng Kai Tan, Despina E. Ganella, Alec Lindsay Ward Dick in Neurochemical Research (2015)