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  1. Article

    Prelimbic Cortical Stimulation Improves Spatial Memory Through Distinct Patterns of Hippocampal Gene Expression in Aged Rats

    Dementia poses major health challenges worldwide, yet current treatments are faced with issues of efficacy and toxicity. Deep brain stimulation (DBS) is a promising non-pharmacological treatment for dementia, ...

    Shawn Zheng Kai Tan, Joveen Neoh, Andrew John Lawrence, Ed Xuekui Wu… in Neurotherapeutics (2020)

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    LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis

    Demyelinating diseases, such as multiple sclerosis, are characterized by the loss of the myelin sheath around neurons, owing to inflammation and gliosis in the central nervous system (CNS). Current treatments ...

    Sha Mi, Bing Hu, Kyungmin Hahm, Yi Luo, Edward Sai Kam Hui, Qiuju Yuan… in Nature Medicine (2007)