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Article
Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells
Chromatin is a dynamic macromolecular structure epigenetically modified to regulate specific gene expression. Altered chromatin function can lead to aberrant expression of growth regulators and may, ultimately...
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Article
Inhibition of Human Breast Cancer Cell Growth by Blockade of the Mevalonate-Protein Prenylation Pathway is not Prevented by Overexpression of Cyclin D1
Overexpression of the cyclin D1 (CCND1) gene, encoding a downstream effector of mitogenic signals that plays a central role in G1 phase progression, is often found in cancerous cells. In sporadic breast cancer (B...
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Article
Gene expression monitoring in hormone-responsive human breast cancer cells during estrogen-induced cell cycle progression
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Article
Sinking of ‘Cavtat’
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Article
Mechanism of X-ray Inhibition of the Sodium Pump in Human Erythrocytes: Adenotriphosphatase Activity of Stromata
PREVIOUS results have shown that X-irradiation of human erythrocytes decreases the active efflux of sodium (sodium pump)1. However, 890 rads and 4,450 rads, which are effective in inducing a 45 and 73 per cent de...