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Article
Open AccessPatient’s thoughts and expectations about centres of expertise for PKU
In the Netherlands (NL) the government assigned 2 hospitals as centres of expertise (CE) for Phenylketonuria (PKU), while in the United Kingdom (UK) and Germany no centres are assigned specifically as PKU CE’s.
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Article
Richter transformation in chronic lymphocytic leukemia (CLL)—a pooled analysis of German CLL Study Group (GCLLSG) front line treatment trials
Richter transformation (RT) is defined as development of aggressive lymphoma in patients (pts) with CLL. The incidence rates of RT among pts with CLL range from 2 to 10%. The aim of this analysis is to report ...
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Article
Residual abdominal lymphadenopathy after intensive frontline chemoimmunotherapy is associated with inferior outcome independently of minimal residual disease status in chronic lymphocytic leukemia
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Article
Open AccessRandomized phase-II trial evaluating induction therapy with idarubicin and etoposide plus sequential or concurrent azacitidine and maintenance therapy with azacitidine
The aim of this randomized phase-II study was to evaluate the effect of substituting cytarabine by azacitidine in intensive induction therapy of patients with acute myeloid leukemia (AML). Patients were random...
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Article
Impact of gender on outcome after chemoimmunotherapy in patients with chronic lymphocytic leukemia: a meta-analysis by the German CLL study group
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Article
Open AccessExperimental Infection of Calves with Escherichia coli O104:H4 outbreak strain
In 2011, a severe outbreak of hemolytic-uremic syndrome was caused by an unusual, highly virulent enterohemorrhagic E. coli (EHEC) O104:H4 strain, which possessed EHEC virulence traits in the genetic background o...
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Article
Randomized comparison of prophylactic and minimal residual disease-triggered imatinib after allogeneic stem cell transplantation for BCR–ABL1-positive acute lymphoblastic leukemia
Minimal residual disease (MRD) after allogeneic stem cell transplantation (SCT) for Ph+ acute lymphoblastic leukemia (ALL) is predictive of relapse. Imatinib administration subsequent to SCT may prevent relaps...
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Article
Retrospective serological survey on selected viral pathogens in wild boar populations in Germany
The objective of this study was to retrospectively evaluate the occurrence of porcine parvovirus (PPV), Aujeszky’s disease virus (ADV), transmissible gastroenteritis virus (TGEV), porcine respiratory coronavir...
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Article
Oral vaccination against classical swine fever with a chimeric Pestivirus: comparative investigations of liquid and lyophilized virus
The goal of this study was to evaluate the efficacy of the chimeric marker vaccine candidate CP7_E2alf in different formulations for oral immunization against classical swine fever (CSF). In the first experime...
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Article
Oral immunisation of wild boar against classical swine fever: uptake studies of new baits and investigations on the stability of lyophilised C-strain vaccine
The aim of this study was to investigate the uptake of new spherical and cuboid baits by wild boar and domestic pigs and to evaluate the stability of lyophilised C-strain vaccine stored at different environmen...
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Article
Obduktionsfrequenz bei plötzlichen Kindstodfällen in der Bundesrepublik Deutschland in den Jahren von 1985 bis 1989
According to the official mortality statistics, the incidence of sudden infant death in the Federal Republic of Germany was 1.55 cases per 1000 live births (1.51–1.59) in the years 1985–1989. However, no infor...
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Article
Assignment of the mouse ataxia-telangiectasia gene (Atm) to mouse Chromosome 9
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Article
New localization of NCAM, proximal to DRD2 at Chromosome 11q23
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Article
Measurement of the absolute luminosity with the ALEPH detector
We report on the absolute luminosity measurement performed with the ALEPH detector at LEP. The systematic errors of the measurements in 1990 are estimated to be 0.6% (experimental) and 0.3% (theoretical).
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Article
Measurement of Tau branching ratios
Using the data accumulated at LEP in 1989 and 1990 with the ALEPH detector, the inclusive and exclusive branching ratios of the τ lepton have been measured assuming lepton universality inZ 0 decays. The inclusive...
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Article
Ataxia-telangiectasia: Linkage analysis in highly inbred Arab and Druze families and differentiation from an ataxia-microcephaly-cataract syndrome
Ataxia-telangiectasia (A-T) is a progressive autosomal recessive disease featuring neurodegeneration, immunodeficiency, chromosomal instability, radiation sensitivity and a highly increased proneness to cancer...
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Article
An investigation into intermittency
The results of an investigation based on ALEPH data,e + e − → hadrons at \(\sqrt s = 91\) GeV, into fluctuations in...
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Article
A study of Bose-Einstein correlations ine + e − annihilation at 91 GeV
This paper describes a study of Bose-Einstein correlations made using the ALEPH detector at LEP. The correlations are found to enhance the two particle differential cross section for pairs of identical pions b...
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Article
Improved measurements of electroweak parameters fromZ decays into fermion pairs
The properties of theZ resonance are measured on the basis of 190 000Z decays into fermion pairs collected with the ALEPH detector at LEP. Assuming lepton universality,M z =(91....
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Article
Measurement of electroweak parameters fromZ decays into fermion pairs
We report on the properties of theZ resonance from 62 500Z decays into fermion pairs collected with the ALEPH detector at LEP, the Large Electron-Positron storage ring at CERN. We findM Z=(91.193±0.016exp±0.030LE...