8 Result(s)

Article

EMBER creates a unified space for independent breast cancer transcriptomic datasets enabling precision oncology

Transcriptomics has revolutionized biomedical research and refined breast cancer subty** and diagnostics. However, wider use in clinical practice is hampered for a number of reasons including the application...

Carlos Ronchi, Syed Haider, Cathrin Brisken in npj Breast Cancer (2024)

Article

Rapid autopsies to enhance metastatic research: the UPTIDER post-mortem tissue donation program

Research on metastatic cancer has been hampered by limited sample availability. Here we present the breast cancer post-mortem tissue donation program UPTIDER and show how it enabled sampling of a median of 31 ...

Tatjana Geukens, Maxim De Schepper, Wouter Van Den Bogaert… in npj Breast Cancer (2024)

Article

TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression

Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive breast cancer. Virtually all women with DCIS are treated, despite evidence suggesting up to half would remain with stable, non-threatenin...

Shayin V. Gibson, Elena Tomas Bort, Lucía Rodríguez-Fernández… in npj Breast Cancer (2023)

Article

RNA sequencing-based single sample predictors of molecular subtype and risk of recurrence for clinical assessment of early-stage breast cancer

Multigene assays for molecular subtypes and biomarkers can aid management of early invasive breast cancer. Using RNA-sequencing we aimed to develop single-sample predictor (SSP) models for clinical markers, su...

Johan Staaf, Jari Häkkinen, Cecilia Hegardt, Lao H. Saal… in npj Breast Cancer (2022)

Article

Reply to Is progesterone a neutral or protective factor for breast cancer?

Cathrin Brisken in Nature Reviews Cancer (2014)