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  1. No Access

    Article

    Cefuroxime and cefuroxime axetil versus amoxicillin plus clavulanic acid in the treatment of lower respiratory tract infections

    In a large multinational study, the clinical and bacteriological efficacy of intravenous cefuroxime 750 mg t.i.d. followed by oral cefuroxime axetil 500 mg b.i.d. was compared to that of amoxicillin plus clavu...

    C. Brambilla, S. Kastanakis, S. Knight… in European Journal of Clinical Microbiology … (1992)

  2. No Access

    Article

    Central airway stenoses: preliminary results of spiral-CT-generated virtual bronchoscopy simulations in 29 patients

    The purpose of this study was to determine the feasibility of using virtual bronchoscopy simulations to depict stenoses of the tracheobronchial tree. Virtual bronchoscopy simulations, based on ray casting, we...

    G. R. Ferretti, J. Knoplioch, I. Bricault, C. Brambilla, M. Coulomb in European Radiology (1997)

  3. No Access

    Article

    Endovascular treatment of superior vena cava obstruction in patients with malignancies

    The aim of this study was to report our experience on the management of superior vena cava obstruction (SVCO) secondary to malignant disease, using endovascular procedures. Twenty-six patients with SVCO due t...

    F. Thony, D. Moro, P. Witmeyer, S. Angiolini, C. Brambilla… in European Radiology (1999)

  4. No Access

    Article

    Moxifloxacin monotherapy compared to amoxicillin-clavulanate plus roxithromycin for nonsevere community-acquired pneumonia in adults with risk factors

    The objective of this study was to assess the efficacy and safety of moxifloxacin versus amoxicillin-clavulanate plus roxithromycin (comparator) in adult community-acquired pneumonia (CAP) patients with risk f...

    H. Portier, C. Brambilla, M. Garre… in European Journal of Clinical Microbiology … (2005)

  5. Article

    Open Access

    Functional serotonin 5–HTTLPR polymorphism is a risk factor for migraine with aura

    In the present work, we report that the functional serotonin transporter gene promoter (5–HTTLPR) polymorphism is involved in migraine pathogenesis. The distribution of 5–HTTLPR genotypes was significantly dif...

    B. Borroni, C. Brambilla, P. Liberini, R. Rao… in The Journal of Headache and Pain (2005)

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  6. No Access

    Article

    E2F-1, Skp2 and cyclin E oncoproteins are upregulated and directly correlated in high-grade neuroendocrine lung tumors

    The transcription factor E2F-1 plays a crucial role in the control of cellular growth. We previously reported its differential pattern of expression in human lung tumors. In this study, we have investigated th...

    C Salon, G Merdzhanova, C Brambilla, E Brambilla, S Gazzeri, B Eymin in Oncogene (2007)

  7. No Access

    Article

    Pulmonary nodule detection on MDCT images: evaluation of diagnostic performance using thin axial images, maximum intensity projections, and computer-assisted detection

    This study aimed at evaluating the diagnostic benefits of maximum intensity projections (MIP) and a commercially available computed-assisted detection system (CAD) for the detection of pulmonary nodules on MDC...

    A. Jankowski, T. Martinelli, J. F. Timsit, C. Brambilla, F. Thony… in European Radiology (2007)

  8. No Access

    Article

    Functional characterization of ATAD2 as a new cancer/testis factor and a predictor of poor prognosis in breast and lung cancers

    Cancer cells frequently express genes normally active in male germ cells. ATAD2 is one of them encoding a conserved factor harbouring an AAA type ATPase domain and a bromodomain. We show here that ATAD2 is highly...

    C Caron, C Lestrat, S Marsal, E Escoffier, S Curtet, V Virolle, P Barbry… in Oncogene (2010)

  9. No Access

    Article

    The transcription factor E2F1 and the SR protein SC35 control the ratio of pro-angiogenic versus antiangiogenic isoforms of vascular endothelial growth factor-A to inhibit neovascularization in vivo

    The transcription factor E2F1 has a crucial role in the control of cell growth and has been shown to regulate neoangiogenesis in a p53-dependent manner through inhibition of activity of the VEGF-A (vascular en...

    G Merdzhanova, S Gout, M Keramidas, V Edmond, J-L Coll, C Brambilla… in Oncogene (2010)

  10. No Access

    Article

    Sumoylation of ING2 regulates the transcription mediated by Sin3A

    ING2 (inhibitor of growth 2) is a candidate tumor-suppressor gene involved in cell cycle control, apoptosis and senescence. Although the functions of ING2 within the chromatin remodeling complex Sin3A/histone ...

    D Ythier, D Larrieu, R Binet, O Binda, C Brambilla, S Gazzeri, R Pedeux in Oncogene (2010)