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  1. No Access

    Article

    Central airway stenoses: preliminary results of spiral-CT-generated virtual bronchoscopy simulations in 29 patients

    The purpose of this study was to determine the feasibility of using virtual bronchoscopy simulations to depict stenoses of the tracheobronchial tree. Virtual bronchoscopy simulations, based on ray casting, we...

    G. R. Ferretti, J. Knoplioch, I. Bricault, C. Brambilla, M. Coulomb in European Radiology (1997)

  2. No Access

    Article

    A retrospective evaluation of HLA-A, B and -DRB1 matching in liver transplantation

    Studies on the influence of histocompatibility in liver transplantation have not produced clear-cut results. We retrospectively studied the influence of HLA-A, B and -DRB1 matching on the survival of 517 live...

    F. Poli, M. Scalamogna, A. Aniasi, C. Brambilla, M. Cardillo in Transplant International (1998)

  3. No Access

    Article

    Endovascular treatment of superior vena cava obstruction in patients with malignancies

    The aim of this study was to report our experience on the management of superior vena cava obstruction (SVCO) secondary to malignant disease, using endovascular procedures. Twenty-six patients with SVCO due t...

    F. Thony, D. Moro, P. Witmeyer, S. Angiolini, C. Brambilla in European Radiology (1999)

  4. No Access

    Article

    Phase I/II study of gemcitabine in association with vinorelbine for metastatic breast cancer

    Background. Gemcitabine (G) and vinorelbine (V) have favorable safety profile and antitumor activity in metastatic breast cancer. To exploit their different mechanism of action and lack of overlap** toxicity, ...

    G. Mariani, P. Tagliabue, P. Zucchinelli in Breast Cancer Research and Treatment (2001)

  5. Article

    Open Access

    Functional serotonin 5–HTTLPR polymorphism is a risk factor for migraine with aura

    In the present work, we report that the functional serotonin transporter gene promoter (5–HTTLPR) polymorphism is involved in migraine pathogenesis. The distribution of 5–HTTLPR genotypes was significantly dif...

    B. Borroni, C. Brambilla, P. Liberini, R. Rao in The Journal of Headache and Pain (2005)

  6. No Access

    Article

    E2F-1, Skp2 and cyclin E oncoproteins are upregulated and directly correlated in high-grade neuroendocrine lung tumors

    The transcription factor E2F-1 plays a crucial role in the control of cellular growth. We previously reported its differential pattern of expression in human lung tumors. In this study, we have investigated th...

    C Salon, G Merdzhanova, C Brambilla, E Brambilla, S Gazzeri, B Eymin in Oncogene (2007)

  7. No Access

    Article

    Pulmonary nodule detection on MDCT images: evaluation of diagnostic performance using thin axial images, maximum intensity projections, and computer-assisted detection

    This study aimed at evaluating the diagnostic benefits of maximum intensity projections (MIP) and a commercially available computed-assisted detection system (CAD) for the detection of pulmonary nodules on MDC...

    A. Jankowski, T. Martinelli, J. F. Timsit, C. Brambilla, F. Thony in European Radiology (2007)

  8. No Access

    Article

    Robot-assisted laparoscopic gastrectomy with D2 dissection for adenocarcinoma: initial experience with 17 patients

    Robot-assisted gastrectomy has been practised so far in very few centres in the world. The aims of this study were to assess the feasibility of robot-assisted gastrectomy for adenocarcinoma with D2 lymph nodal...

    R. Pugliese, D. Maggioni, F. Sansonna, G. C. Ferrari in Journal of Robotic Surgery (2008)

  9. No Access

    Article

    Functional characterization of ATAD2 as a new cancer/testis factor and a predictor of poor prognosis in breast and lung cancers

    Cancer cells frequently express genes normally active in male germ cells. ATAD2 is one of them encoding a conserved factor harbouring an AAA type ATPase domain and a bromodomain. We show here that ATAD2 is highly...

    C Caron, C Lestrat, S Marsal, E Escoffier, S Curtet, V Virolle, P Barbry in Oncogene (2010)

  10. No Access

    Article

    The transcription factor E2F1 and the SR protein SC35 control the ratio of pro-angiogenic versus antiangiogenic isoforms of vascular endothelial growth factor-A to inhibit neovascularization in vivo

    The transcription factor E2F1 has a crucial role in the control of cell growth and has been shown to regulate neoangiogenesis in a p53-dependent manner through inhibition of activity of the VEGF-A (vascular en...

    G Merdzhanova, S Gout, M Keramidas, V Edmond, J-L Coll, C Brambilla in Oncogene (2010)

  11. No Access

    Article

    Sumoylation of ING2 regulates the transcription mediated by Sin3A

    ING2 (inhibitor of growth 2) is a candidate tumor-suppressor gene involved in cell cycle control, apoptosis and senescence. Although the functions of ING2 within the chromatin remodeling complex Sin3A/histone ...

    D Ythier, D Larrieu, R Binet, O Binda, C Brambilla, S Gazzeri, R Pedeux in Oncogene (2010)