29 Result(s)

Article

The DNA sequence and biology of human chromosome 19

Chromosome 19 has the highest gene density of all human chromosomes, more than double the genome-wide average. The large clustered gene families, corresponding high G + C content, CpG islands and density of re...

Jane Grimwood, Laurie A. Gordon, Anne Olsen, Astrid Terry, Jeremy Schmutz… in Nature (2004)

Article

Cannabinoids and gene expression during brain development

Cannabis is the most commonly used illicit drug in western societies, in particular among young people. It is consumed even by women during pregnancy and lactation, which result in a variety of disturbances in...

Javier Fernández-ruiz, María Gómez, Mariluz Hernández… in Neurotoxicity Research (2004)

Article

Skin Cancer Induced by Arsenic in the Water

Hugo Cabrera, María Gómez in Journal of Cutaneous Medicine and Surgery:… (2003)

Article

Loss of cannabinoid CB₁ receptors in the basal ganglia in the late akinetic phase of rats with experimental Huntington’s disease

We have recently examined the status of the endocannabinoid transmission in the basal ganglia in Huntington’s disease (HD) using a rat model generated by bilateral intrastriatal injections of 3-nitropropionic ...

Isabel Lastres-Becker, María Gómez, Rosario de Miguel… in Neurotoxicity Research (2002)

Article

Changes in prodynorphin and POMC gene expression in several brain regions of rat fetuses prenatally exposed to Δ-tetrahydrocannabinol

Recently, we demonstrated that prenatal Δ-tetrahydrocannabinol (Δ⁹-THC) exposure alters proenkephalin mRNA levels in several brain regions of rat fetuses. In the present study, we analyzed mRNA levels of the two ...

Alberto Pérez-Rosado, María Gómez, Jorge Manzanares… in Neurotoxicity Research (2002)

Article

Endogenous polyamines modulate Ca²⁺ channel activity in guinea-pig intestinal smooth muscle

The polyamines spermine and spermidine inhibit L-type Ca²⁺ channels in whole-cell recordings from guinea-pig ileum cells (Gomez and Hellstrand, Pflügers Arch, 430:501–507, 1995 [4]). To study whether they modula...

Maria Gomez, Per Hellstrand in Pflügers Archiv (1999)

Article

Identification of a novel inflammation-protective locus in the Fischer rat

Inbred LEW/N rats are relatively susceptible, while histocompatible inbred F344/N rats are relatively resistant to development of a wide variety of inflammatory diseases in response to a range of pro-inflamma...

Samuel Listwak, Ruth M. Barrientos, George Koike, Soumitra Ghosh… in Mammalian Genome (1999)

Article

Effects of polyamines on voltage-activated calcium channels in guinea-pig intestinal smooth muscle

Effects of polyamines on the spontaneous mechanical and electrical activity of guinea-pig intestinal smooth muscle were studied. Spermine and spermidine inhibited action potential generation and contractions, ...

Maria Gomez, Per Hellstrand in Pflügers Archiv (1995)

Article

Accumulation of 3-(phenylamino)alanine, a constituent in l-tryptophan products implicated in eosinophilia-myalgia syndrome, in blood and organs of the Lewis rats

3-(Phenylamino)alanine (PAA), a newly discovered impurity in case-associated l-tryptophan tablets, has been investigated as a possible contributing factor in the etiology of eosinophilia-myalgia syndrome (EMS). W...

Junko Adachi, Maria Gomez, Craig C. Smith, Esther M. Sternberg in Archives of Toxicology (1995)