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Article
Open AccessThe androgen receptor/filamin A complex as a target in prostate cancer microenvironment
Prostate cancer represents the major cause of cancer-related death in men and patients frequently develop drug-resistance and metastatic disease. Most studies focus on hormone-resistance mechanisms related to ...
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Article
Open AccessNumerical Evaluation of Advanced Laser Control Strategies Influence on Residual Stresses for Laser Powder Bed Fusion Systems
Process-dependent residual stresses are one of the main burdens to a widespread adoption of laser powder bed fusion technology in industry. Residual stresses are directly influenced by process parameters, such...
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Article
Open AccessDiffusion–reaction compartmental models formulated in a continuum mechanics framework: application to COVID-19, mathematical analysis, and numerical study
The outbreak of COVID-19 in 2020 has led to a surge in interest in the research of the mathematical modeling of epidemics. Many of the introduced models are so-called compartmental models, in which the total quan...
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Article
Open Access3D Automatic Segmentation of Aortic Computed Tomography Angiography Combining Multi-View 2D Convolutional Neural Networks
The quantitative analysis of contrast-enhanced Computed Tomography Angiography (CTA) is essential to assess aortic anatomy, identify pathologies, and perform preoperative planning in vascular surgery. To overc...
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Article
Basis of the Lattice Boltzmann Method for Additive Manufacturing
Additive manufacturing (or 3D printing) is constantly growing as an innovative process for the production of complex-shape components. Among the seven recognized 3D printing technologies, powder bed fusion (PB...
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Article
Feasibility of 3D printed salivary duct models for sialendoscopic skills training: preliminary report
To explore the feasibility of 3D printed salivary duct models for the sialendoscopic skills training.
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Chapter and Conference Paper
Mechanical Characterization of Cement-Based Mortar Used in 3DCP Including Early-Age Creep Effects
Digital fabrication techniques combined with suitable cementitious materials have successfully led to the implementation of innovative manufacturing processes for concrete-like products. However, although sign...
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Article
An overview on 3D printing for abdominal surgery
Three-dimensional (3D) printing is a disruptive technology that is quickly spreading to many fields, including healthcare. In this context, it allows the creation of graspable, patient-specific, anatomical mod...
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Article
Optimization clustering technique for PieceWise Uniform Transformation Field Analysis homogenization of viscoplastic composites
Aim of the present study is to propose an enhanced method for the domain decomposition (clustering) of the representative volume element (RVE) of composite materials to be used with homogenization techniques, ...
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Article
Graded-material design based on phase-field and topology optimization
In the present work we introduce a novel graded-material design based on phase-field and topology optimization. The main novelty of this work comes from the introduction of an additional phase-field variable i...
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Article
Accurate Prediction of Melt Pool Shapes in Laser Powder Bed Fusion by the Non-Linear Temperature Equation Including Phase Changes
In this contribution, we validate a physical model based on a transient temperature equation (including latent heat), w.r.t. the experimental set AMB2018-02 provided within the additive manufacturing benchmark...
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Article
Open AccessAndrogens Induce Invasiveness of Triple Negative Breast Cancer Cells Through AR/Src/PI3-K Complex Assembly
Breast cancer (BC) is still characterized by high morbidity and mortality. A specific BC subtype named triple negative BC (TNBC) lacks estrogen and progesterone receptors (ER and PR, respectively) and is chara...
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Article
Reversed Auxiliary Flow to Reduce Embolism Risk During TAVI: A Computational Simulation and Experimental Study
Endovascular treatments, such as transcatheter aortic valve implantation (TAVI), carry a risk of embolization due to debris dislodgement during various procedural steps. Although embolic filters are already av...
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Chapter
Hospital Factory for Manufacturing Customised, Patient-Specific 3D Anatomo-Functional Models and Prostheses
The fabrication of personalised prostheses tailored on each patient is one of the major needs and key issues for the future of several surgical specialties. Moreover, the production of patient-specific anatomo...
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Chapter
Predictive Computational Models of Transcatheter Aortic Valve Implantation
In the last decades, biomechanical computer models have been increasingly adopted in the cardiovascular field either to improve the knowledge of pathological conditions or to anticipate possible outcomes of th...
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Article
Explicit parametric solutions of lattice structures with proper generalized decomposition (PGD)
Architectured materials (or metamaterials) are constituted by a unit-cell with a complex structural design repeated periodically forming a bulk material with emergent mechanical properties. One may obtain spec...
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Article
The clinical use of 3D printing in surgery
The use of 3D printing is gaining considerable success in many medical fields including surgery. Here, the technology was introduced for increasing the level of anatomical understanding thanks to the inherent ...
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Article
Erratum to: Computational Methods for Elastoplasticity: An Overview of Conventional and Less‑Conventional Approaches
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Article
Computational Methods for Elastoplasticity: An Overview of Conventional and Less-Conventional Approaches
The need of accurately reproducing the behaviour of elastoplastic materials in computational environments for the solution of engineering problems motivates the development of efficient and robust numerical sc...
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Article
Open AccessPlanar Timoshenko-like model for multilayer non-prismatic beams
This paper aims at proposing a Timoshenko-like model for planar multilayer (i.e., non-homogeneous) non-prismatic beams. The main peculiarity of multilayer non-prismatic beams is a non-trivial stress distributi...