38 Result(s)
within
English
Paul D. Brown
Article
Medicine & Public Health
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Article
Neurocognition in individuals with incidentally-identified meningioma
Meningiomas are primary intracranial tumors that are often asymptomatic. To our knowledge, no study has attempted to describe neurocognitive function in patients with incidentally-discovered meningioma. We uti...
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Patterns of care and treatment outcomes in older adults with low grade glioma: a 50-year experience
The purpose of this study was to identify changes in presentation, treatment and outcomes of older patients with low-grade glioma (LGG) over the past 50 years. 94 adults aged 55 or older upon diagnosis of a WH...
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Radiotherapy with concurrent temozolomide for the management of extraneural metastases in pituitary carcinoma
Pituitary carcinomas (PC) are uncommon neuroendocrine tumors, accounting for 0.1 % of all pituitary tumors. The diagnosis of PC is based on the presence of metastases from a pituitary adenoma, and not by local...
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Can the spinal instability neoplastic score prior to spinal radiosurgery predict compression fractures following stereotactic spinal radiosurgery for metastatic spinal tumor?: a post hoc analysis of prospective phase II single-institution trials
The aim of this study was to determine the predictability of vertebral compression fracture (VCF) development applying the spinal instability neoplastic score (SINS) prior to delivery of stereotactic spinal ra...
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Exploring primary brain tumor patient and caregiver needs and preferences in brief educational and support opportunities
A primary brain tumor patient and caregiver survey was completed to investigate interest in brief support opportunities, focused on education, memory training, and healthy co**, during a routine clinical vis...
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Supratentorial gross-totally resected non-anaplastic ependymoma: population based patterns of care and outcomes analysis
Observation following gross-total resection (GTR) for non-anaplastic supratentorial ependymomas is often advocated based on small, retrospective series. The purpose of this study is to perform a population-bas...
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The effect of tumor subtype on the time from primary diagnosis to development of brain metastases and survival in patients with breast cancer
Our group has previously published the Diagnosis-Specific Graded Prognostic Assessment (GPA) showing the prognostic factors associated with survival in patients with brain metastases (BM). The purpose of this ...
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Temozolomide use in adult patients with gliosarcoma: an evolving clinical practice
The purpose of this study is to determine the factors that impact overall survival (OS) in adult patients with gliosarcoma in the modern era treated at a single institution compared with a cohort from the SEER...
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Pilocytic astrocytoma survival in adults: analysis of the Surveillance, Epidemiology, and End Results Program of the National Cancer Institute
Pilocytic astrocytoma is a WHO grade 1 brain tumor common in children. Relatively little is known about the behavior of pilocytic astrocytomas in adult patients, largely due to the rarity of pilocytic astrocyt...
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Phase II NCCTG trial of RT + irinotecan and adjuvant BCNU plus irinotecan for newly diagnosed GBM
Irinotecan has radiosensitizing effects and shows synergism with nitrosoureas. We performed a Phase II study of RT and irinotecan, followed by BCNU plus irinotecan in newly-diagnosed GBM. The MTD for patients ...
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Comparing neuropsychological tasks to optimize brief cognitive batteries for brain tumor clinical trials
Neuropsychological tests are increasingly being used as outcome measures in clinical trials of brain tumor therapies. This study informs development of brief neurocognitive batteries for clinical trials by ide...
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Radiation-induced optic neuritis after pituitary adenoma radiosurgery in a patient with multiple sclerosis: case report
Objective and Importance To describe a rare case of optic neuritis onset after Gamma Knife stereotactic radiosurgery. Clinical Presentation Nine years after transsphenoidal subtotal resec...
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Open AccessAntimicrobial resistance of Escherichia coliisolates from broiler chickens and humans
Antimicrobial usage is considered the most important factor promoting the emergence, selection and dissemination of antimicrobial-resistant microorganisms in both veterinary and human medicine. The aim of this...
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Prospective Study of Quality of Life in Adults with Newly Diagnosed High-grade Gliomas
To assess baseline quality of life (QOL) and its prognostic importance for adults with newly diagnosed high-grade gliomas, we analyzed QOL and outcome data prospectively collected in three phase II high-grade ...
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Choroid Plexus Papillomas: A Single Institutional Experience
Objective: To determine the long-term outcome of resected choroid plexus papillomas (CPPs).
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Properly Selected Patients with Multiple Brain Metastases May Benefit from Aggressive Treatment of their Intracranial Disease
To determine whether properly selected patients with multiple brain metastases benefit from aggressive treatment of their intracranial disease, we reviewed 52 patients having stereotactic radiosurgery (SRS), t...
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Metastatic Spinal Cord Compression In Patients With Colorectal Cancer
Background. A retrospective study was performed to examine the outcome of patients with colorectal cancer who had metastatic spinal cord compression (MSCC) and received radiation therapy (RT).
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The results of radiotherapy for brainstem tumors
Objective: This analysis was performed to examine the outcome of adult and pediatric patients with brainstem tumors. Methods and materials: Forty patients with brainstem glioma were evaluated retrospectively. ...
