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  1. Article

    Open Access

    Joint EANM/EANO/RANO/SNMMI practice guideline/procedure standards for diagnostics and therapy (theranostics) of meningiomas using radiolabeled somatostatin receptor ligands: version 1.0

    To provide practice guideline/procedure standards for diagnostics and therapy (theranostics) of meningiomas using radiolabeled somatostatin receptor (SSTR) ligands.

    Nathalie L. Albert, Matthias Preusser… in European Journal of Nuclear Medicine and M… (2024)

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  2. Article

    Open Access

    Carcinoembryonic antigen-expressing oncolytic measles virus derivative in recurrent glioblastoma: a phase 1 trial

    Measles virus (MV) vaccine strains have shown significant preclinical antitumor activity against glioblastoma (GBM), the most lethal glioma histology. In this first in human trial (NCT00390299), a carcinoembry...

    Evanthia Galanis, Katharine E. Dooley, S. Keith Anderson… in Nature Communications (2024)

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  3. No Access

    Article

    The utility of PET for detecting corticotropinomas in Cushing disease: a sco** review

    While magnetic resonance imaging (MRI) is the current standard imaging method for diagnosing and localizing corticotropinomas in Cushing disease, it can fail to detect adenomas in up to 40% of cases. Recently,...

    Megan M. J. Bauman, Jeffrey P. Graves, Daniel Jeremiah Harrison… in Neurosurgical Review (2023)

  4. No Access

    Article

    Spontaneous intracranial hypotension: updates from diagnosis to treatment

    Spontaneous intracranial hypotension (SIH) is caused by spinal cerebrospinal fluid (CSF) leaks, which result in continued loss of CSF volume and multiple debilitating clinical manifestations. The estimated ann...

    Paul J. Farnsworth, Ajay A. Madhavan, Jared T. Verdoorn, Darya P. Shlapak… in Neuroradiology (2023)

  5. No Access

    Article

    Clinical experience and outcomes in patients with pineal parenchymal tumor of intermediate differentiation (PPTID): a single-institution analysis

    Pineal parenchymal tumor of intermediate differentiation (PPTID) is a neoplasm of pinealocyte origin and of intermediate differentiation (WHO grade 2 or 3). Treatment selection and prognostication is challengi...

    Mason Webb, Derek R. Johnson, Anita Mahajan, Paul Brown… in Journal of Neuro-Oncology (2022)

  6. No Access

    Article

    Intracranial long-term complications of radiation therapy: an image-based review

    Radiation therapy is commonly utilized in the majority of solid cancers and many hematologic malignancies and other disorders. While it has an undeniably major role in improving cancer survival, radiation ther...

    Carrie M. Carr, John C. Benson, David R. DeLone, Felix E. Diehn… in Neuroradiology (2021)

  7. No Access

    Article

    Temozolomide desensitization followed by metronomic dosing in patients with hypersensitivity

    Temozolomide is the most effective chemotherapy for malignant glioma. Hypersensitivity requiring interruption of therapy may significantly impact patient survival. We have successfully employed temozolomide de...

    Bryan J. Neth, Michael W. Ruff, Joon H. Uhm… in Cancer Chemotherapy and Pharmacology (2020)

  8. No Access

    Chapter

    Review of WHO 2016 Changes to Classification of Gliomas; Incorporation of Molecular Markers

    In 2016, the World Health Organization (WHO) updated its brain tumor classification system to recognize the importance of key genetic alterations in glioma, incorporating these features into the definitions of...

    Derek R. Johnson, Caterina Giannini, Timothy J. Kaufmann in Glioma Imaging (2020)

  9. No Access

    Article

    Plenty of calcification: imaging characterization of polymorphous low-grade neuroepithelial tumor of the young

    Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a recently described epileptogenic neoplasm. As the name implies, PLNTYs are indolent tumors most often encountered in the pediatric or youn...

    Derek R. Johnson, Caterina Giannini, Robert B. Jenkins, Dong Kun Kim… in Neuroradiology (2019)

  10. No Access

    Article

    PET Imaging of Hepatocellular Carcinoma

    Positron emission tomography has not traditionally played a major role in the evaluation of hepatocellular carcinoma (HCC). Owing to high background liver uptake and molecular mechanisms within HCC lesions, up...

    Eric C. Ehman, Scott M. Thompson, Brian T. Welch… in Current Radiology Reports (2019)

  11. No Access

    Article

    There is an exception to every rule—T2-FLAIR mismatch sign in gliomas

    The T2-FLAIR mismatch sign, in which a low-grade glioma is hyperintense on T2-weighted MR and centrally hypointense on T2-weighted FLAIR MR, has been reported as 100% specific for IDH-mutant astrocytomas in sever...

    Derek R. Johnson, Timothy J. Kaufmann, Sohil H. Patel, Andrew S. Chi… in Neuroradiology (2019)

  12. Article

    Open Access

    Pittsburgh compound B (PiB) PET imaging of meningioma and other intracranial tumors

    Meningiomas are the most common intracranial tumors. Diagnosis by MRI is generally straightforward, but lack of imaging specificity can present a diagnostic dilemma, particularly in patients with cancer. We re...

    Derek R. Johnson, Christopher H. Hunt, Mark A. Nathan… in Journal of Neuro-Oncology (2018)

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  13. No Access

    Article

    Uptake of AV-1451 in meningiomas

    AV-1451 is an imaging agent labeled with the positron-emitting radiolabel Fluorine-18. 18F-AV-1451 binds paired helical filament tau (PHF-tau), a pathology related to Alzheimer’s disease. In our study of AV-14...

    Tyler J. Bruinsma, Derek R. Johnson, ** Fang… in Annals of Nuclear Medicine (2017)

  14. No Access

    Article

    Socioeconomic status and glioblastoma risk: a population-based analysis

    Socioeconomic status (SES) is associated with risk of various cancer types because of correlation between SES and causal factors or increased case ascertainment, or both. Studies evaluating the association be...

    Alyx B. Porter, Daniel H. Lachance, Derek R. Johnson in Cancer Causes & Control (2015)

  15. No Access

    Article

    Incorporation of Prognostic and Predictive Factors Into Glioma Clinical Trials

    Treatment of brain tumors is increasingly informed by biomarkers that predict patient prognosis and response to therapy. While this progress represents a great opportunity for the field of neuro-oncology, it a...

    Derek R. Johnson, Evanthia Galanis in Current Oncology Reports (2013)

  16. No Access

    Article

    Pilocytic astrocytoma survival in adults: analysis of the Surveillance, Epidemiology, and End Results Program of the National Cancer Institute

    Pilocytic astrocytoma is a WHO grade 1 brain tumor common in children. Relatively little is known about the behavior of pilocytic astrocytomas in adult patients, largely due to the rarity of pilocytic astrocyt...

    Derek R. Johnson, Paul D. Brown, Evanthia Galanis… in Journal of Neuro-Oncology (2012)

  17. No Access

    Article

    Glioblastoma survival in the United States before and during the temozolomide era

    The standard-of-care treatment for newly diagnosed glioblastoma changed in 2005, when radiation therapy plus temozolomide chemotherapy replaced radiation therapy alone. It is not yet clear how this change in t...

    Derek R. Johnson, Brian Patrick O’Neill in Journal of Neuro-Oncology (2012)

  18. No Access

    Chapter

    Recent Medical Management of Glioblastoma

    This chapter contains an overview of standard of care and experimental chemotherapy treatments for glioblastoma multiforme (GBM). We discuss the role of alkylating agents, focusing primarily on temozolomide (T...

    Derek R. Johnson, Susan M. Chang in Glioma (2012)