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A target-triggered strand displacement-assisted target recycling based on carbon dots-based fluorescent probe and MSNs@PDA nanoparticles for miRNA amplified detection and fluorescence imaging
A target-triggered strand displacement-assisted target recycling based on carbon dots-based fluorescent probe and mesoporous silica...
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GraphTar: applying word2vec and graph neural networks to miRNA target prediction
BackgroundMicroRNAs (miRNAs) are short, non-coding RNA molecules that regulate gene expression by binding to specific mRNAs, inhibiting their...
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miRNA mediated regulation of nitrogen response and nitrogen use efficiency of plants: the case of wheat
Nitrogen (N) is needed for plant growth and development and is the major limiting nutrient due to its higher demand in agricultural production...
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Interrogation of Functional miRNA-Target Interactions by CRISPR/Cas9 Genome Engineering
Posttranscriptional silencing by microRNAs (miRNAs) is a critical constituent of eukaryotic gene regulation. miRNAs are short (~22 nt) noncoding RNAs...
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MTAGCN: predicting miRNA-target associations in Camellia sinensis var. assamica through graph convolution neural network
BackgroundMircoRNAs (miRNAs) play a central role in diverse biological processes of Camellia sinensis var.assamica (CSA) through their associations...
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nf-core/circrna: a portable workflow for the quantification, miRNA target prediction and differential expression analysis of circular RNAs
BackgroundCircular RNAs (circRNAs) are a class of covalenty closed non-coding RNAs that have garnered increased attention from the research community...
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miRNA Biogenesis and Regulation of Diseases: An Updated Overview
MicroRNAs (miRNAs) are small RNA molecules, with their role in gene silencing and translational repression by binding to the target mRNAs. Since it...
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A simple and label-free proximity-catalytic hairpin reaction-based method for sensitive and miRNA analysis
Aberrant expression of microRNAs (miRNAs) has been shown to be linked to several crucial biological processes, including as carcinogenesis,...
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MicroRNA–Target Identification: A Combinatorial In Silico Approach
Contemporary computational target prediction tools with their distinctive properties and stringency have been playing a vital role in pursuing...
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Multifunctional elastin-like polypeptide nanocarriers for efficient miRNA delivery in cancer therapy
BackgroundThe exogenous delivery of miRNA to mimic and restore miRNA-34a activity in various cancer models holds significant promise in cancer...
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Almond miRNA Expression and Horticultural Implications
From the past, till now various improved almond cultivars with desired traits have been introduced through breeding programs based on classical and...
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Interface-constrained catalytic hairpin assembly permits highly sensitive SERS signaling of miRNA
The rapid and precise monitoring of peripheral blood miRNA levels holds paramount importance for disease diagnosis and treatment monitoring. In this...
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Sensitive and reliable miRNA analysis based on cyclic reverse transcription and CRISPR-Cas12a-assisted signal cycle
MicroRNAs (miRNAs), a category of small molecules that possess significant regulatory capabilities, have been extensively employed as biomarkers in...
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Regulation of adipogenesis by exosomal milk miRNA
Milk is a rich source of miRNA packaged in exosomes. Evidence for the systemic uptake and tissue distribution of milk exosomes was reported in...
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EMCMDA: predicting miRNA-disease associations via efficient matrix completion
Abundant researches have consistently illustrated the crucial role of microRNAs (miRNAs) in a wide array of essential biological processes....
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Rapid and ultrasensitive miRNA detection by combining endonuclease reactions in a rolling circle amplification (RCA)–based hairpin DNA fluorescent assay
MicroRNA (miRNA) sensing strategies employing rolling circle amplification (RCA) coupled with the hairpin DNA (HD) probe–mediated FRET assay have...
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MiRNA-192-5p-targeted activated leukocyte cell adhesion molecule improved inflammatory injury of neonatal necrotizing enterocolitis
BackgroundNeonatal necrotizing enterocolitis (NEC) is a common gastrointestinal emergency in neonates. MiRNA-192-5p was found associated with...
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Evaluation of miRNA Expression in 3D In Vitro Scaffold-Based Cancer Models
Accumulating experimental evidence suggests that 3D in vitro cancer models strengthen our understanding of vital processes in the tumor...
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Significant role of circRNA BBS9 in chronic obstructive pulmonary disease via miRNA-103a-3p/BCL2L13
BackgroundVarious studies have shown that circular RNA (circRNA) plays a pivotal role in chronic obstructive pulmonary disease (COPD). We aimed to...
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Double hairpin-assembled probe-mediating catalytic hairpin assembly and primer exchange reaction for sensitive and label-free miRNA analysis in gastric carcinoma
The aberrant expression of microRNA (miRNA) is closely associated with various pathological processes, such as the development of gastric cancer....
