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Supercritical fluid chromatography coupled to high-resolution tandem mass spectrometry: an innovative one-run method for the comprehensive assessment of chocolate quality and authenticity
To assess chocolate quality and authenticity comprehensively, a combination of various analytical procedures is involved, thereby making the process...
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Determination of Metabolites of Selected Thermally Treated Food-derived Mutagens and Carcinogens in Biological Material
Thermal processing of food can lead to the formation of compounds harmful to human health. These include heterocyclic aromatic amines (HAAs) formed... -
Ion Mobility Spectrometry in Clinical and Emergency Setting: Research and Potential Applications
Interest in the use of GC-IMS for the detection of volatiles has seen a rapid expansion over the last decade. The following chapter will focus on... -
Effects of ferrous sulfate and methyl jasmonate treatment on the content of 2-(2-phenethyl)chromones in Aquilaria sinensis
The 2-(2-phenylethyl) chromones are the main characteristic constituents for the fragrance and pharmacological activities of agarwood. Iron and...
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Determination of Pyrethroid Insecticides Metabolites in Wastewater
Pyrethroids are one of the most frequently used insecticides, particularly due to their low toxicity and high efficiency in small doses. Human... -
Determination of the Glyphosate Content in Liquid and Dry Formulations by HPLC-UV: Pre-column Derivation with 9-Fluorenylmethyl Chloroformate (FMOC)
Monitoring the glyphosate content of glyphosate-based herbicides requires simple, inexpensive and accessible analytical methods. The objective of...
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A sensitive, robust method for determining natural and synthetic hormones in surface and wastewaters by continuous solid-phase extraction–gas chromatography–mass spectrometry
Over recent decades, steroidal estrogens have become an emerging and very serious issue as they pose a serious threat to living organisms, soil,...
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Optimization and Validation in Liquid Chromatography Using Design of Experiments
Faced to the large number of potential factors in liquid chromatography, the analyst is often led to determine through his experience the parameters...
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Site-Specified Conjugating Technology and Application
Conjugation strategy is a very important consideration when designing antibody-drug conjugates (ADCs). Site-specified conjugation is the conjugation... -
Lipidomics Analysis Reveals a Protective Effect of Myriocin on Cerebral Ischemia/Reperfusion Model Rats
Ceramide accumulation has been associated with ischemic stroke. Myriocin is an effective serine palmitoyltransferase (SPT) inhibitor that reduces...
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Highly sensitive indirect competitive enzyme-linked immunosorbent assay based on a monoclonal antibody against saikosaponin b2 for quality control of Kampo medicines containing Bupleuri radix
Saikosaponins are naturally occurring oleanane-type triterpenoids that are found in Bupleuri radix (root of Bupleurum falcatum ) and exhibit a broad...
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Analytical Strategies and Applications in Lipidomics
Lipidomics is a field of study aiming at a comprehensive analysis of a set of lipids in biological systems. This includes both quantitative and... -
Complementary information concerning the suspected interindividual transmission of GW1516, a substance prohibited in sport, through intimate contact: a case report
PurposeInadvertent and/or unknowing exposure to drugs and drug residues has been frequently debated in situations of so-called adverse analytical...
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Polyesters of 14-Hydroxylated Taxoids Found for the First Time in Taxus canadensis Intact Plants
AbstractTaxane diterpenoids (taxoids) are found only in representatives of the Taxaceae family (different yew species); however, the unique structure...
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Metabolite-Based Genome-Wide Association Studies of Large-Scale Metabolome Analysis to Illustrate Alterations in the Metabolite Landscape of Plants upon Responses to Stresses
Given that anthropogenic activities are evoking a profound effect on the climate resulting in more extreme events such as severe drought and heat... -
Analytical Strategies and Applications in Lipidomics
Lipidomics is a field of study aiming at a comprehensive analysis of a set of lipids in biological systems. This includes both quantitative and... -
Influence of Synthesis Conditions on the Performance of Palladium–Copper Ethanol-to-Butanol Conversion Catalysts
AbstractThe influence of the synthesis conditions on the performance of Pd–Cu ethanol-to-butanol conversion catalysts was studied. The optimum...
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Molecularly imprinted dispersive micro solid-phase extraction and tandem derivatization for the determination of histamine in fermented wines
Histamine causes allergic reactions and can serve as an indicator for assessing food quality. This study designed and developed a dispersive micro...
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Chromatographic and spectroscopic study of impurities present in thebaine obtained from Papaver bracteatum Lindl.
Thebaine is an important opiate alkaloid derived from opium that can be converted into various pharmaceutical compounds. However, only a few studies...
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Gas Chromatography–Mass Spectrometry Combined with Successive Dilution for the Determination of Preservatives in Pharmaceuticals
AbstractSome aspects of sample pretreatment and instrumental approaches for the quantification of sorbic acid ( SA ), benzoic acid ( BA ), methylparaben...