Search
Search Results
-
Dose Adjustment of Concomitant Antiseizure Medications During Cenobamate Treatment: Expert Opinion Consensus Recommendations
IntroductionOur objective was to provide expert consensus recommendations to improve treatment tolerability through dose adjustments of concomitant...
-
Impact of Antiseizure Medications on Appetite and Weight in Children
There are numerous potential factors that may affect growth in children with epilepsy, and these must be evaluated in any child with appetite and...
-
Antiseizure Drugs and Seizure Aggravation
Specific situations exist where the addition of antiseizure medications (ASM) worsens seizures instead of reducing or eliminating them. Common...
-
A Review of the Selected and Newer Antiseizure Medications Used in Childhood Epilepsies
There have been additions of newer antiseizure medications in the armamentarium of clinicians for the management of epilepsy. The newer antiseizure...
-
Perampanel’s forgiveness factor in a variable medication adherence paradigm in a rat model of chronic epilepsy
BackgroundPoor medication adherence contributes to increased morbidity and mortality in patients with epilepsy and may be under-addressed in clinical...
-
Clinically Relevant Interactions Between Ritonavir-Boosted Nirmatrelvir and Concomitant Antiseizure Medications: Implications for the Management of COVID-19 in Patients with Epilepsy
Ritonavir-boosted nirmatrelvir (RBN) has been authorized recently in several countries as an orally active anti-SARS-CoV-2 treatment for patients at...
-
A pilot study on identifying gene signatures as markers for predicting patient response to antiseizure medications
The majority of the biomarkers were associated with the diagnosis of epilepsy and few of them can be applied to predict the response to antiseizure...
-
Incidence of Acute Renal Failure in Patients Using Levetiracetam Versus Other Antiseizure Medications: A Voluntary Post-Authorization Safety Study
IntroductionAcute kidney injury is an expected adverse drug reaction listed in the European Union (EU) Summary of Product Characteristics (SmPC) for...
-
Attention-Deficit Hyperactivity Disorder (ADHD) Medication Use Trajectories Among Women in the Perinatal Period
BackgroundAn increasing number of women of reproductive age are treated with attention-deficit hyperactivity disorder (ADHD) medication; however,...
-
Additional Results from Two Randomized, Placebo-Controlled Trials of Stiripentol in Dravet Syndrome Highlight a Rapid Antiseizure Efficacy with Longer Seizure-Free Periods
IntroductionThe efficacy of stiripentol in Dravet syndrome children was evidenced in two randomized, double-blind, placebo-controlled, phase 3...
-
In utero exposure to ADHD medication and long-term offspring outcomes
Attention Deficit Hyperactivity Disorder (ADHD) medication is increasingly being used during pregnancy. Concerns have been raised as to whether ADHD...
-
Seizure control by adding on other anti-seizure medication on seizure during levetiracetam administration in patients with glioma-related epilepsy
BackgroundEpilepsy is a major symptom in patients with glioma. Levetiracetam (LEV) is recognized as a first-line treatment for glioma-related...
-
Prognosis and management of acute symptomatic seizures: a prospective, multicenter, observational study
BackgroundAcute symptomatic epileptic seizures are frequently seen in neurocritical care. To prevent subsequent unprovoked seizures, long-term...
-
The Pharmacology and Clinical Efficacy of Antiseizure Medications: From Bromide Salts to Cenobamate and Beyond
Epilepsy is one of the most common and disabling chronic neurological disorders. Antiseizure medications (ASMs), previously referred to as...
-
Psychotropic Medication Use in Children and Youth with Autism Enrolled in Medicaid
Children with autism frequently present with complex mental health diagnoses and psychotropic medications are often a component of comprehensive...
-
Does SANAD II help with gender-specific problems in epilepsy treatment?—English Version
Gender-specific differences in the treatment of epilepsy are a continuous challenge in the choice of treatment. Earlier studies on antiseizure...
-
Outcomes of a Medication Optimization Virtual Interdisciplinary Geriatric Specialist (MOVING) Program: A Feasibility Study
BackgroundAdverse drug events among older adults result in significant mortality, morbidity and cost. This harm may be mitigated with appropriate...
-
Response to Sodium Channel blocking Antiseizure medications and coding polymorphisms of Sodium Channel genes in Taiwanese epilepsy patients
BackgroundMany antiseizure medications (ASMs) control seizures by blocking voltage-dependent sodium channels. Polymorphisms of sodium channel genes...