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Neuroprotective effect of apelin-13 and other apelin forms—a review
Neurodegenerative diseases, which occur when neurons begin to deteriorate, affect millions of people worldwide. These age-related disorders are...
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Vitamin K: a Potential Neuroprotective Agent
Neurodegeneration, a progressive disease due to the arrested development of atrophy and regression of neuron function, is the most common disorder...
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Exploring the Active Components of Ziziphus jujuba Mill. in Treatment of Depression by Network Pharmacology Combined with Neuroprotective Effects in SH-SY5Y Cells
Depression is a common mental health disease, with the characteristics of significant and persistent low mood. Traditionally, Ziziphus jujuba Mill . ...
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Antioxidant Properties, Neuroprotective Effects and in Vitro Safety Evaluation of New Pyrrole Derivatives
The paper is focused on safety evaluation, antioxidant activity and neuroprotective properties determination of newly synthesized substituted...
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Is metformin neuroprotective against diabetes mellitus-induced neurodegeneration? An updated graphical review of molecular basis
Diabetes mellitus (DM) is a metabolic disease that activates several molecular pathways involved in neurodegenerative disorders. Metformin, an...
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Unraveling the mechanistic interplay of mediators orchestrating the neuroprotective potential of harmine
Neurodegenerative diseases (NDDs) encompass a range of conditions characterized by the specific dysfunction and continual decline of neurons, glial...
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Anti-amnesic and Neuroprotective Potential of Genistein Against Alzheimer’s Disease
Alzheimer’s disease, the most prevalent neurodegenerative disorder, is characterized by language deficits, impairment of problem-solving ability,...
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Neuroprotective Effects of Cannabidiol Under Cerebral Ischemic Conditions
AbstractThe lack of blood flow during cerebral ischemic conditions results in multiple and intricate pathophysiological mechanisms including...
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Neuroprotective and Neuroregenerative Properties of Dimeric Dipeptide Mimetics of Individual NGF and BDNF Loops Under Conditions of an Experimental Ischemic Stroke Model
This article reviews our work devoted to studying the biochemical properties of original dimeric dipeptide mimetics of nerve growth factor (NGF) and...
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Neuroprotective Effect of Lutein in Scopolamine-Induced Alzheimer’s Disease in Mice and Zebrafish
Lutein, a dietary antioxidant, can be a potent treatment for Alzheimer’s disease. In this study, the neuroprotective effect of lutein against...
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Review on pharmacological effects of gastrodin
Gastrodia elata Blume is a well-known traditional Chinese medicine that is mainly used to treat diseases related to the nervous system, such as...
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Mechanistic interplay of various mediators involved in mediating the neuroprotective effect of daphnetin
Daphnetin is a 7, 8 dihydroxy coumarin isolated from different medicinal plants of the Thymelaeaceae family and exhibits copious pharmacological...
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Protective Effects of Quercetin in Combination with Donepezil against H2O2-Induced Oxidative Stress in Glioblastoma Cells
Polyphenols are natural antioxidants found in the human diet, which are known to have protective effects against neurodegenerative diseases by...
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Integrated LC-MS/MS Method and Network Pharmacology for Exploring the Mechanism of Neuroprotective Effect of Ginsenoside Rc in Oxygen-Glucose Deprivation/Reperfusion Injury
Ginsenoside Rc is one of the active components of “nao-mai-tong,” which is a traditional Chinese medicine prescription widely used in the treatment...
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Neuroprotective effects of mirtazapine and imipramine and their effect in pro- and anti-apoptotic gene expression in human neuroblastoma cells
BackgroundExperimental and clinical studies indicate that neuronal death with the presence of high levels of reactive oxygen species are present in...
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Effects of N-acetylcysteine and acetyl-l-carnitine on acute PTZ-induced seizures in larval and adult zebrafish
BackgroundEpilepsy is a prevalent neurological disease, affecting approximately 1–2% of the global population. The hallmark of epilepsy is the...
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Design and Synthesis of Dipeptide Nerve Growth Factor Loop 1 Mimetics and In Vitro Studies of their Neuroprotective and Differentiation-Inducing Activities
Previous studies at the V. V. Zakusov Science Research Institute of Pharmacology created a dimeric dipeptide mimetic of the most exposed fourth loop...
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The protective effects of statins in traumatic brain injury
Traumatic brain injury (TBI), often referred to as the “silent epidemic”, is the most common cause of mortality and morbidity worldwide among all...
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Luteolin for neurodegenerative diseases: a review
Neurodegenerative diseases such as Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and multiple sclerosis affect millions of people...
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Memory Protecting Herbs: Centella asiatica and Bacopa monnieri in the Fight Against Alzheimer's Disease
This study presents a systematic comparison between Centella asiatica (L.) Urb., Apiaceae, and Bacopa monnieri (L.) Wettst . , Plantaginaceae, two...
