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Approaches to supratentorial brain tumours in children
The differential diagnosis of supratentorial brain tumours in children can be challenging, especially considering the recent changes to the WHO...
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Clinico-Demographic Profile of Paediatric Patients with Primary Intracranial Tumours in South India
The central and peripheral nervous system cancers are the second most common cancers among the paediatric population (0–14 years). The non-specific...
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Central nervous system tumours in neonates: what should the neonatologist know?
Central nervous system (CNS) tumours in neonates are relatively rare and present differently when compared with those occurring later in childhood in...
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Collision tumours: a meningioma and not oedema, but an oligodendroglioma
BackgroundIntracranial collision tumours represent a very rare entity. We hereby report a case involving the coexistence of a meningioma and an...
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Preoperative word-finding difficulties in children with posterior fossa tumours: a European cross-sectional study
PurposePosterior fossa tumour surgery in children entails a high risk for severe speech and language impairments, but few studies have investigated...
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Nystagmus in children with primary brain tumours in Denmark between 2007 and 2017
BackgroundThe aim of the study was to evaluate the prevalence, clinical characteristics, and diagnostic importance of nystagmus in children with...
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Understanding the activity of antibody–drug conjugates in primary and secondary brain tumours
Antibody–drug conjugates (ADCs), a class of targeted cancer therapeutics combining monoclonal antibodies with a cytotoxic payload via a chemical...
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Paediatric supratentorial tumours do not cause microstructural alterations in contralateral white matter: a preliminary study
Background and purposeIntracranial tumours in children can exhibit different characteristics compared to those in adults. Understanding the...
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Comparison of microscopic full-laminectomy (open surgery) and microendoscopic minimally invasive hemilaminectomy for thoracic extramedullary spinal tumours
BackgroundMinimally invasive treatments for spinal cord tumours are common. The aim of this study was to compare the perioperative outcomes of...
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Current use and potential role of radioguided surgery in brain tumours
PurposeThe aim of this mini-review is to discuss the possible role of radioguided surgery in brain tumours and, in particular, in gliomas.
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Solid tumours showing oligoprogression to immune checkpoint inhibitors have the potential for abscopal effects
PurposeGiven the uncertainty surrounding the abscopal effect (AE), it is imperative to identify promising treatment targets. In this study, we aimed...
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Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours
Therapies with genetically modified T cells that express chimeric antigen receptors (CARs) specific for CD19 or B cell maturation antigen (BCMA) are...
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Long term quality of life outcomes following surgical resection alone for benign paediatric intracranial tumours
PurposeSurvivors of paediatric intracranial tumours are at increased risk of psychosocial, neuro-developmental, and functional impairment. This study...
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Microsurgical anatomy of the anterior cerebral artery and the arterial supply of the cingulate gyrus
PurposeThe cingulate gyrus is a potential surgical area to treat tumours, psychiatric diseases, intractable pain and vascular malformations. The aim...
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2021 WHO classification of tumours of the central nervous system: a review for the neuroradiologist
The fifth edition of the World Health Organization Classification of Tumours of the Central Nervous System (WHO CNS5) published in 2021 builds on the...
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Advances and Technical Standards in Neurosurgery Volume 50
In this book, internationally recognised experts provide an update on some important basic and technical aspects of neurosurgery. Intracranial...
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A review of solitary fibrous tumours of the orbit and ocular adnexa
Solitary fibrous tumour (SFT) is an uncommon spindle cell tumour of mesenchymal origin characterised by NAB2-STAT6 gene fusion. Although it was first...
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Clinical implications of the 2021 edition of the WHO classification of central nervous system tumours
A new edition of the WHO classification of tumours of the CNS was published in 2021. Although the previous edition of this classification was...
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The effectiveness and safety of proton beam radiation therapy in children and young adults with Central Nervous System (CNS) tumours: a systematic review
BackgroundCentral nervous system (CNS) tumours account for around 25% of childhood neoplasms. With multi-modal therapy, 5-year survival is at around...
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Neuroendoscopy in the management of pineal region tumours in children
IntroductionPineal region tumours (PRTs) are more common in children and represent a wide variety of lesions. The practise of a radiation test dose...