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Synaptic configuration and reconfiguration in the neocortex are spatiotemporally selective
Brain computation relies on the neural networks. Neurons extend the neurites such as dendrites and axons, and the contacts of these neurites that...
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Effect of current conduction for local epileptiform discharges in patients with temporal lobe epilepsy
ObjectivesThe effects of current conduction were researched to confirm that it can decrease focal epileptogenicity in patients with temporal lobe...
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Evidence of brain metabolism redistribution from neocortex to primitive brain structures in early acute COVID-19 respiratory syndrome
BackgroundNeuropsychiatric sequelae of COVID-19 have been widely documented in patients with severe neurological symptoms during the chronic or...
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Epilepsy surgery without lipoma removal for temporal lobe epilepsy associated with lipoma in the Sylvian fissure
Epileptic seizure is the common symptom associated with lipomas in the Sylvian fissure (Sylvian lipomas). Removal of these lipomas carries risks of...
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Low-grade glioma of the temporal lobe and tumor-related epilepsy in children
PurposeLow-grade glioma is the most common brain tumor among children and adolescents. When these tumors arise in the temporal lobe, patients...
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Metabolic phenoty** of hand automatisms in mesial temporal lobe epilepsy
PurposeHand automatisms (HA) are common clinical manifestations in mesial temporal lobe epilepsy. However, the location of the symptomatogenic zone...
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Differences in whole-brain metabolism are associated with the expression of genes related to neurovascular unit integrity and synaptic plasticity in temporal lobe epilepsy
PurposeTemporal lobe epilepsy (TLE) is a common, polygenic epilepsy syndrome that involves glucose hypometabolism in the epileptogenic zone. However,...
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Autophagy-related genes in mesial temporal lobe epilepsy: an integrated bioinformatics analysis
BackgroundAutophagy plays essential roles in the development and pathogenesis of mesial temporal lobe epilepsy (mTLE). In this research, we aim to...
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Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease caused by repetitive head impacts (RHI) and pathologically defined as neuronal...
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Map** connectivity fingerprints for presurgical evaluation of temporal lobe epilepsy
BackgroundSurgery may render temporal lobe epilepsy (TLE) patients seizure-free. However, TLE is a heterogenous entity and surgical prognosis varies...
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Right temporal lobe epilepsy surgery activates suppressed post-traumatic stress disorder 31 years after a robbery
Hippocampus and amygdala play central roles in the development of post-traumatic stress disorder (PTSD). Changes in neurological structures due to...
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Human herpesvirus 6B infection in mesial temporal lobe epilepsy: a meta-analysis
BackgroundWhether human herpesvirus 6B (HHV-6B) can affect mesial temporal lobe epilepsy (MTLE) remains controversial. The present meta-analysis was...
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Sequential pattern of sublayer formation in the paleocortex and neocortex
The piriform cortex (paleocortex) is the olfactory cortex or the primary cortex for the sense of smell. It receives the olfactory input from the...
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Ictal onset stereoelectroencephalography patterns in temporal lobe epilepsy: type, distribution, and prognostic value
ObjectiveThe aim of this study was to investigate the different ictal onset stereoelectroencephalography patterns (IOPs) in patients with...
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Temporal and spatial changes in reactive astrogliosis examined by 18F-THK5351 positron emission tomography in a patient with severe traumatic brain injury
BackgroundThe positron emission tomography (PET) radioligand 18 F-THK5351 is now used to evaluate monoamine oxidase B expression in the reactive...
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Temporal lobe epilepsy associated with human herpes virus 6
Human herpes virus 6 (HHV-6) is a ubiquitous and most common pathogen that affects humans. Human herpes virus 6B (HHV-6B) is a wide spread human...
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Usefulness of magnetic resonance spectroscopy in mesial temporal sclerosis: a systematic review
BackgroundMagnetic resonance spectroscopy (MRS) provides non-invasive information about metabolic features in different regions of the brain affected...
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Effects of escitalopram on synaptic density in the healthy human brain: a randomized controlled trial
Selective serotonin reuptake inhibitors (SSRIs) are widely used for treating neuropsychiatric disorders. However, the exact mechanism of action and...
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Possible roles of deep cortical neurons and oligodendrocytes in the neural basis of human sociality
Sociality is an instinctive property of organisms that live in relation to others and is a complex characteristic of higher order brain functions....