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Reduction of false positives using zone-specific prostate-specific antigen density for prostate MRI-based biopsy decision strategies
ObjectivesTo develop and test zone-specific prostate-specific antigen density (sPSAD) combined with PI-RADS to guide prostate biopsy decision...
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Value of serum free prostate-specific antigen density in the diagnosis of prostate cancer
PurposeTo investigate the value of serum free prostate-specific antigen density (fPSAD) in the diagnosis of prostate cancer (PCa).
Methods ...
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Prostate-specific membrane antigen-positron emission tomography (PSMA-PET) of prostate cancer: current and emerging applications
Prostate-specific membrane antigen-positron emission tomography (PSMA-PET) is transforming the management of patients with prostate cancer. In...
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Increase of prostate-specific antigen doubling time predicts survival in metastatic castration-resistant prostate cancer patients undergoing radium therapy
ObjectiveRadium-223 (Ra-223) is an important treatment modality for bone-dominant metastatic castration-resistant prostate cancer (mCRPC). However,...
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Study of prostate-specific antigen levels during salvage radiotherapy after prostate cancer surgery
BackgroundAdministration of adjuvant or salvage radiotherapy (RT) after prostate cancer (PCa) surgery is supported by clinical evidence and is a...
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Prostate-specific membrane antigen radioguided surgery with negative histopathology: an in-depth analysis
PurposeTo identify reasons for negative histopathology of specimens from prostate-specific membrane antigen (PSMA) radioguided surgery (PSMA-RGS) in...
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Head-to-head comparison of prostate-specific membrane antigen PET and multiparametric MRI in the diagnosis of pretreatment patients with prostate cancer: a meta-analysis
ObjectivesTo compare prostate-specific membrane antigen (PSMA) PET with multiparametric MRI (mpMRI) in the diagnosis of pretreatment prostate cancer...
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Heterogeneity of prostate-specific membrane antigen (PSMA) and PSMA-ligand uptake detection combining autoradiography and postoperative pathology in primary prostate cancer
BackgroundTargeting prostate-specific membrane antigen (PSMA) has been highly successful for imaging and treatment of prostate cancer. However,...
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Amide Proton Transfer-weighted MRI combined with serum prostate-specific antigen levels for differentiating malignant prostate lesions from benign prostate lesions: a retrospective cohort study
BackgroundEarly diagnosis of prostate cancer improves its prognosis, while it is essential to upgrade screening tools. This study aimed to explore...
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The impact of prostate volume estimation on the risk‐adapted biopsy decision based on prostate-specific antigen density and magnetic resonance imaging score
PurposeUtility of prostate-specific antigen density (PSAd) for risk-stratification to avoid unnecessary biopsy remains unclear due to the lack of...
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Clinical value of prostate health index as an indicator for recommending magnetic resonance imaging in patients with gray-zone prostate-specific antigen level
PurposeTo evaluate the usefulness of prostate health index (PHI) as an indicator for recommending magnetic resonance imaging (MRI) in patients with...
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Diagnostic performance of MRI in detecting prostate cancer in patients with prostate-specific antigen levels of 4–10 ng/mL: a systematic review and meta-analysis
ObjectiveTo investigate the diagnostic performance of MRI in detecting clinically significant prostate cancer (csPCa) and prostate cancer (PCa) in...
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Relationship between prostate-specific antigen, alkaline phosphatase levels, and time-to-tumor shrinkage: understanding the progression of prostate cancer in a longitudinal study
BackgroundThis study delves into the complex interplay among prostate-specific antigen, alkaline phosphatase, and the temporal dynamics of tumor...
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The effect of limited english proficiency on prostate-specific antigen screening in American men
PurposeTo evaluate how limited English proficiency (LEP) impacts the prevalence of prostate-specific antigen (PSA) screening in a contemporary,...
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Prostate cancer risk prediction based on clinical factors and prostate-specific antigen
IntroductionThe incidence rate of prostate cancer (PCa) has continued to rise in Korea. This study aimed to construct and evaluate a 5-year PCa risk...
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Cost-Effectiveness Modeling of Prostate-Specific Membrane Antigen Positron Emission Tomography with Piflufolastat F 18 for the Initial Diagnosis of Patients with Prostate Cancer in the United States
Background and objectivesPiflufolastat F 18 is a novel prostate-specific membrane antigen (PSMA)-targeted positron emission tomography (PET)...
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Prostate-specific membrane antigen (PSMA) radioguided surgery in prostate cancer: An overview of current application and future perspectives
Radical prostatectomy (RP) with or without pelvic lymph node dissection (PLND) is the most frequent approach to treat men affected by prostate cancer...
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Evaluation of gastrin-releasing peptide receptor, prostate-specific membrane antigen, and neurotensin receptor 1 as potential biomarkers for accurate prostate cancer stratified diagnosis
BackgroundStudies on single-target PET imaging of gastrin-releasing peptide receptor (GRPR), prostate-specific membrane antigen (PSMA), or...
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Sensitivity and specificity of prostate-specific antigen and its surrogates towards the detection of prostate cancer in sub-Saharan Africa: a systematic review with meta-analysis
BackgroundRacial disparities associated with pathogenesis and progression of prostate cancer makes a global diagnostic prostate-specific antigen...
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Prostate Specific Membrane Antigen Expression in a Syngeneic Breast Cancer Mouse Model
PurposeProstate specific membrane antigen (PSMA) has been studied in human breast cancer (BCa) biopsies, however, lack of data on PSMA expression in...
