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DOCK–PET: database of CNS kinetic parameters in the healthy human brain for existing PET tracers
PurposeInformation about developed positron emission tomography (PET) tracers and obtained clinical PET images is publicly available in a database....
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Metabolic kinetic modeling of [11C]methionine based on total-body PET in multiple myeloma
PurposeMultiple myeloma (MM) is a malignant disease characterized by the secretion of monoclonal immunoglobulins and has a high demand for amino...
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Comparison of tracer kinetic models for 68Ga-PSMA-11 PET in intermediate-risk primary prostate cancer patients
Background68 Ga-PSMA-11 positron emission tomography enables the detection of primary, recurrent, and metastatic prostate cancer. Regional...
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PET KinetiX—A Software Solution for PET Parametric Imaging at the Whole Field of View Level
Kinetic modeling represents the ultimate foundations of PET quantitative imaging, a unique opportunity to better characterize the diseases or prevent...
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Feasibility of using abbreviated scan protocols with population-based input functions for accurate kinetic modeling of [18F]-FDG datasets from a long axial FOV PET scanner
BackgroundAccurate kinetic modeling of 18F-fluorodeoxyglucose ([ 18 F]-FDG) positron emission tomography (PET) data requires accurate knowledge of the...
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Dynamic total-body PET/CT imaging with reduced acquisition time shows acceptable performance in quantification of [18F]FDG tumor kinetic metrics
PurposeTo investigate the feasibility of reducing the acquisition time for continuous dynamic positron emission tomography (PET) while retaining...
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Drug characteristics derived from kinetic modeling: combined 11C-UCB-J human PET imaging with levetiracetam and brivaracetam occupancy of SV2A
BackgroundAntiepileptic drugs, levetiracetam (LEV) and brivaracetam (BRV), bind to synaptic vesicle glycoprotein 2A (SV2A). In their anti-seizure...
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Combining deep learning with a kinetic model to predict dynamic PET images and generate parametric images
BackgroundDynamic positron emission tomography (PET) images are useful in clinical practice because they can be used to calculate the metabolic...
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Short-term PET-derived kinetic estimation for the diagnosis of hepatocellular carcinoma: a combination of the maximum-slope method and dual-input three-compartment model
BackgroundKinetic estimation provides fitted parameters related to blood flow perfusion and fluorine-18-fluorodeoxyglucose ( 18 F-FDG) transport and...
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Non-invasive quantification of 18F-florbetaben with total-body EXPLORER PET
BackgroundKinetic modeling of 18 F-florbetaben provides important quantification of brain amyloid deposition in research and clinical settings but...
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Kinetic modeling and parameter estimation of TSPO PET imaging in the human brain
PurposeTranslocator protein 18-kDa (TSPO) imaging with positron emission tomography (PET) is widely used in research studies of brain diseases that...
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Spatially constrained kinetic modeling with dual reference tissues improves 18F-flortaucipir PET in studies of Alzheimer disease
PurposeRecent studies have shown that standard compartmental models using plasma input or the cerebellum reference tissue input are generally not...
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Dynamic chaotic gravitational search algorithm-based kinetic parameter estimation of hepatocellular carcinoma on 18F-FDG PET/CT
BackgroundKinetic parameters estimated with dynamic 18 F-FDG PET/CT can help to characterize hepatocellular carcinoma (HCC). We aim to evaluate the...
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Kinetic Evaluation of the Hypoxia Radiotracers [18F]FMISO and [18F]FAZA in Dogs with Spontaneous Tumors Using Dynamic PET/CT Imaging
PurposeWe evaluated the kinetics of the hypoxia PET radiotracers, [18F]fluoromisonidazole ([18F]FMISO) and [18F]fluoroazomycin-arabinoside...
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An update on the use of image-derived input functions for human PET studies: new hopes or old illusions?
BackgroundThe need for arterial blood data in quantitative PET research limits the wider usability of this imaging method in clinical research...
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Quantitation of dynamic total-body PET imaging: recent developments and future perspectives
BackgroundPositron emission tomography (PET) scanning is an important diagnostic imaging technique used in disease diagnosis, therapy planning,...
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Cardiac amyloidosis characterization by kinetic model fitting on [18F]florbetaben PET images
ObjectiveTo evaluate the feasibility of kinetic modeling-based approaches from [18F]-Flobetaben dynamic PET images as a non-invasive diagnostic...
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Hybridizing machine learning in survival analysis of cardiac PET/CT imaging
BackgroundMachine Learning (ML) allows integration of the numerous variables delivered by cardiac PET/CT, while traditional survival analysis can...
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Radiomics predictive modeling from dual-time-point FDG PET Ki parametric maps: application to chemotherapy response in lymphoma
BackgroundTo investigate the use of dynamic radiomics features derived from dual-time-point (DTP-feature) [ 18 F]FDG PET metabolic uptake rate K i ...
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Combined whole-body dynamic and static PET/CT with low-dose [18F]PSMA-1007 in prostate cancer patients
AimIn addition to significant improvements in sensitivity and image quality, the recent introduction of long axial field-of-view (LAFOV) PET/CT...
