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Nanomedicine’s transformative impact on anti-diabetic drug discovery: an appraisal
The role of nanotechnology in the diagnostics and therapeutics of diabetes has been widely known. In this paper, the authors have tried to...
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Nanoreceptors promote mutant p53 protein degradation by mimicking selective autophagy receptors
In some cancers mutant p53 promotes the occurrence, development, metastasis and drug resistance of tumours, with targeted protein degradation seen as...
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SARS-CoV-2 Spike Protein: A Review of Structure, Function, Care, Vaccines, and Possible Inhibitors Designed by Molecular Modeling
In Wuhan, Hubei Province, China, a new species of coronavirus has emerged, defined as SARS-CoV-2, which causes severe acute respiratory syndrome,...
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Fibronectin-derived protein forms a protein corona on gold nanoparticles: synthesis, Raman and optical properties of a new plasmonic nanocarrier
Synthetic fibronectin III-derived protein scaffolds represent a new generation of proteins that can overcome some clinical limitations of therapeutic...
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The Yin and Yang of the protein corona on the delivery journey of nanoparticles
Nanoparticles-based drug delivery systems have attracted significant attention in biomedical fields because they can deliver loaded cargoes to the...
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Dynamically crosslinked nanocapsules for the efficient and serum-resistant cytosolic protein delivery
Intracellular protein delivery is critical to the development of protein-based biopharmaceuticals and therapies. However, current delivery vectors...
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MicroRNA functional metal-organic framework nanocomposite for efficient inhibition of drug-resistant breast cancer cells
The most prevalent malignant neoplasm identified in females is breast cancer. Multidrug resistance is a significant obstacle for breast cancer...
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Post-insertion technique to introduce targeting moieties in milk exosomes for targeted drug delivery
BackgroundRecently, increased attention has been given on exosomes as ideal nanocarriers of drugs owing to their intrinsic properties that facilitate...
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Protein nanoparticles directed cancer imaging and therapy
Cancer has been a serious threat to human health. Among drug delivery carriers, protein nanoparticles are unique because of their mild and...
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Polymeric Nanofibers for Drug Delivery Applications: A Recent Review
With the rapid development of biomaterials and biotechnologies, various functional materials-based drug delivery systems (DDS) are developed to...
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Innovations and challenges of polyphenol-based smart drug delivery systems
Polyphenols, as widely existing natural bioactive products, provide a vast array of advanced biomedical applications attributing to their potential...
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A Review on the Recent Developments in Electrospinned Nanofibers for Drug Delivery
One of the newest areas of research in the biomedical field is the investigation of innovative medication drug delivery methods through nanofibers....
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Emerging Nanomaterials for Cancer Targeting and Drug Delivery
Nature of core materials used, physicochemical characters, surface engineering, targeting moieties, biocompatibility, bioavailability, low toxicity,...
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Machine Learning Approaches to 3D Models for Drug Screening
The creation of precise, functional 3D tissues can enable effective drug screening as well as advancements in regenerative medicine. However, the...
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Anticancer platinum-drug delivered by mesenchymal stromal cells improves its activity on glioblastoma
BackgroundGlioblastoma multiforme (GBM) is nowadays the most aggressive tumor affecting brain in adults with a very poor prognosis due to the limited...
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Ethyl acetate fraction of Rhododendron arboreum as potential therapeutic against drug-resistant bacterial isolates through experimental and in silico approach
Rhododendron arboreum (Ericaceae) is an evergreen shrub, predominantly present in the Himalayas, and used traditionally for various ailments. The...
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Protein-modified nanomaterials: emerging trends in skin wound healing
Prolonged inflammation can impede wound healing, which is regulated by several proteins and cytokines, including IL-4, IL-10, IL-13, and TGF-β....
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Polylactic acid (PLA)-based materials: a review on the synthesis and drug delivery applications
Controlled drug release is an important aspect of biomedical applications of polymer materials. Polylactic acid (PLA)-based materials have been...
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The protein corona from nanomedicine to environmental science
The protein corona spontaneously develops and evolves on the surface of nanoscale materials when they are exposed to biological environments,...
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Antimicrobial Peptides, An Alternative Antimicrobial Agent Against Multi-drug-Resistant Microbes: Source, Application, and Potential
Pathogenic microorganisms are often associated with infectious diseases in humans, plants, or animals. Over the past 100 years, antibiotics have been...