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GraphTar: applying word2vec and graph neural networks to miRNA target prediction
BackgroundMicroRNAs (miRNAs) are short, non-coding RNA molecules that regulate gene expression by binding to specific mRNAs, inhibiting their...
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Interrogation of Functional miRNA-Target Interactions by CRISPR/Cas9 Genome Engineering
Posttranscriptional silencing by microRNAs (miRNAs) is a critical constituent of eukaryotic gene regulation. miRNAs are short (~22 nt) noncoding RNAs...
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miRNA mediated regulation of nitrogen response and nitrogen use efficiency of plants: the case of wheat
Nitrogen (N) is needed for plant growth and development and is the major limiting nutrient due to its higher demand in agricultural production...
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MTAGCN: predicting miRNA-target associations in Camellia sinensis var. assamica through graph convolution neural network
BackgroundMircoRNAs (miRNAs) play a central role in diverse biological processes of Camellia sinensis var.assamica (CSA) through their associations...
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nf-core/circrna: a portable workflow for the quantification, miRNA target prediction and differential expression analysis of circular RNAs
BackgroundCircular RNAs (circRNAs) are a class of covalenty closed non-coding RNAs that have garnered increased attention from the research community...
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miRNA Biogenesis and Regulation of Diseases: An Updated Overview
MicroRNAs (miRNAs) are small RNA molecules, with their role in gene silencing and translational repression by binding to the target mRNAs. Since it...
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MicroRNA–Target Identification: A Combinatorial In Silico Approach
Contemporary computational target prediction tools with their distinctive properties and stringency have been playing a vital role in pursuing...
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Almond miRNA Expression and Horticultural Implications
From the past, till now various improved almond cultivars with desired traits have been introduced through breeding programs based on classical and...
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Evaluation of miRNA Expression in 3D In Vitro Scaffold-Based Cancer Models
Accumulating experimental evidence suggests that 3D in vitro cancer models strengthen our understanding of vital processes in the tumor...
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Novel and deleterious nucleotide variations in the HAND1 gene probably affect miRNA target sites and protein function in pediatric patients with congenital heart disease
BackgroundCongenital heart disease (CHD) is the most prevalent developmental defect and principal cause of infant mortality and affects cardiac and...
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A sensitive one-pot ROA assay for rapid miRNA detection
MicroRNAs (miRNAs) and short RNA fragments (18–25 nt) are crucial biomarkers in biological research and disease diagnostics. However, their accurate...
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Metapath-Based Deep Convolutional Neural Network for Predicting miRNA-Target Association on Heterogeneous Network
Predicting the interactions between microRNAs (miRNAs) and target genes is of great significance for understanding the regulatory mechanism of miRNA...
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Assessment of Cell Cytotoxicity in 3D Biomaterial Scaffolds Following miRNA Transfection
Assessment of cell cytotoxicity following transfection of cells with microRNA (miRNA) is an essential step in the evaluation of basic miRNA...
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An Integrated Bioinformatics and Functional Approach for miRNA Validation
MicroRNAs (miRNAs) are small (20–24 nucleotides) non-coding ribo-regulatory molecules with significant roles in regulating target mRNA and long...
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Detection of transcriptome-wide microRNA–target interactions in single cells with agoTRIBE
MicroRNAs (miRNAs) exert their gene regulatory effects on numerous biological processes based on their selection of target transcripts. Current...
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Isothermal exponential amplification reactions triggered by circular templates (cEXPAR) targeting miRNA
BackgroundIsothermal exponential amplification reaction (EXPAR) is an emerging amplification technique that is most frequently used to amplify...
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The emerging roles of miRNA-mediated autophagy in ovarian cancer
Ovarian cancer is one of the common tumors of the female reproductive organs. It has a high mortality rate, is highly heterogeneous, and early...
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Comparative genome-wide analysis of circular RNAs in Brassica napus L.: target-site versus non-target-site resistance to herbicide stress
Circular RNAs (circRNAs), a class of non-coding RNA molecules, are recognized for their unique functions; however, their responses to herbicide...
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An Efficient CRISPR-Cas9 Method to Knock Out MiRNA Expression in Xenopus Tropicalis
In recent years CRISPR-Cas9 knockouts (KO) have become increasingly utilized to study gene function. MicroRNAs (miRNAs) are short noncoding RNAs,...
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Association between Yili goose sperm motility and expression profiles of mRNA and miRNA in testis
BackgroundThe study was conducted to find out the candidate microRNA (miRNA) and genes that associated with sperm motility of Yili goose through...
