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Assessment of Heat-Shock Protein Hsp70 Colocalization with Markers of Tumor Stem-Like Cells
AbstractThe search of biomarkers for early diagnosis and theranostics of glioblastoma multiforme (GBM) due to the aggressiveness of the disease is an...
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Transfection of Heat Shock Protein 70 kDa (HSP70)
Heat shock protein 70 kDa (HSP70) is a major protein family in the cell protections against stress-induced denaturation and aggregation and in the...
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Regulation of the heat shock response by heat shock transcription factors
The heat shock response is characterized by a rapid and robust increase in heat shock proteins upon exposure to protein-damaging stresses. This...
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Contribution of HIF-1α to Heat Shock Response by Transcriptional Regulation of HSF1/HSP70 Signaling Pathway in Pacific Oyster, Crassostrea gigas
Ocean temperature rising drastically threatens the adaptation and survival of marine organisms, causing serious ecological impacts and economic...
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Systematic analysis of Heat Shock Protein 70 (HSP70) gene family in radish and potential roles in stress tolerance
The 70 kD heat shock proteins (HSP70s) represent a class of molecular chaperones that are widely distributed in all kingdoms of life, which play...
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Insilico-based genome-wide identification and structural characterization of heat shock proteins 70 (HSP70) in cowpea (Vigna unguiculata L.)
Heat shock protein 70 is conserved a family of ubiquitously expressed proteins that help plants to withstand the major abiotic stresses. Although HSP70 ...
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HSP70-HSP90 Chaperone Networking in Protein-Misfolding Disease
Molecular chaperones and their associated co-chaperones are essential in health and disease as they are key facilitators of protein-folding, quality...
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Heat shock protein 70 is associated with duration of cell proliferation in early pod development of soybean
Pod is an important organ for seed production in soybean. Pod size varies among soybean cultivars, but the mechanism is largely unknown. Here we...
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Can heat shock protein 70 (HSP70) serve as biomarkers in Antarctica for future ocean acidification, warming and salinity stress?
The Antarctic Peninsula is one of the fastest-warming places on Earth. Elevated sea water temperatures cause glacier and sea ice melting. When...
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Heat-shock proteins, oxidative stress, and antioxidants in one-humped camels
One-humped camels ( Camelus dromedarius ) exhibit remarkable adaptability to harsh desert environments through various physiological adaptations. This...
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Fungal heat shock proteins: molecular phylogenetic insights into the host takeover
Heat shock proteins are constitutively expressed chaperones induced by cellular stress, such as changes in temperature, pH, and osmolarity. These...
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Heat Shock Proteins in Cancer Diagnostics
AbstractWith the growing number of cancer cases, new tools are required to obtain extensive molecular profiles of patients to help identify the...
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Heat Shock Proteins in Plant Immunity
AbstractHeat shock proteins (HSPs) are widely distributed among prokaryotic and eukaryotic organisms, and their function is not limited to protection...
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Heat Shock Proteins and HSF1 in Ferroptosis
When cells are exposed to various stressors, such as heat, toxins, or oxidative stress, heat shock transcription factor 1 (HSF1) becomes activated...
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Tardigrade small heat shock proteins can limit desiccation-induced protein aggregation
Small heat shock proteins (sHSPs) are chaperones with well-characterized roles in heat stress, but potential roles for sHSPs in desiccation tolerance...
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Preventive Administration of the Heat Shock Protein Hsp70 Relieves Endotoxemia-Induced Febrile Reaction in Pigeons (
Columba livia ) and RatsAbstractThe stress-inducible 70 kDa heat shock protein (Hsp70) can exert a protective effect on endotoxemia and sepsis due to its ability to interact...
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Ectopic BH3-Only Protein Bim Associates with Hsp70 to Regulate Yeast Mitophagy
AbstractMitophagy, a form of selective autophagy, plays an essential role to maintain a population of healthy and functional mitochondria for normal...
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A Novel Heat Shock Protein 70-Based Vaccine Prepared from DC Tumor Fusion Cells: An Update
We have developed an enhanced molecular chaperone-based vaccine through rapid isolation of Hsp70 peptide complexes after the fusion of tumor and...
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Calmodulin, Calcium/Calmodulin-Dependent Kinases-1 and 2 Regulate Expression of the Heat Shock Proteins for Heat Shock Tolerance and Pheromone Signaling Genes for Sexual Development in Neurospora crassa
Calmodulin (CaM) is a primary Ca 2+ sensor that binds and activates numerous target proteins and regulates several cellular processes in eukaryotes....
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Genome wide and evolutionary analysis of heat shock protein 70 proteins in tomato and their role in response to heat and drought stress
Heat shock protein 70 (HSP70) proteins play a crucial role in mitigating the detrimental effects of abiotic stresses in plants. In the present study,...
