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TAC–TIC, a high-throughput genetics method to identify triggers or blockers of bacterial toxin–antitoxin systems
Toxin–antitoxin systems (TAs) are abundant in bacterial chromosomes and can arrest growth under stress, but usually remain inactive. TAs have been...
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New approaches towards the synthesis of 1,2,3,4-tetrahydro isoquinoline-3-phosphonic acid (TicP)
Two new strategies for the efficient synthesis of racemic 1,2,3,4-tetrahydroisoquinoline-3-phosphonic acid (Tic P ) (±)- 2 have been developed. The...
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Assessing photosynthetic uptake of total inorganic carbon in an Ecklonia cava dominated seaweed artificial reef: Population- and community-level metabolisms
With increasing climate crisis concerns, interest in primary production of marine ecosystems is also increasing. Recently, artificial transplantation...
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Soil Carbon Dynamics Under Different Ecosystems of Ooty Region in the Western Ghats Biodiversity Hotspot of India
Large-scale deforestation and increased land use change (LUC) over the past few years have shattered the ecological balance of the Western Ghats by...
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rtcisE2F promotes the self-renewal and metastasis of liver tumor-initiating cells via N6-methyladenosine-dependent E2F3/E2F6 mRNA stability
Liver cancer is highly heterogeneous, and the tumor tissue harbors a variety of cell types. Liver tumor initiating cells (TICs) well contribute to...
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A preliminary study on the effects of **aoyao San on neurological function and 5-HT2A mRNA expression in mice with Tourette syndrome
BackgroundTourette syndrome (TS) is a chronic neuropsychiatric disorder, also known as multiple tic syndrome. TS is associated with the serotonin...
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Optimization of production parameters of particle gluing on internal bonding strength of particleboards using machine learning technology
The particleboard (PB) production is an extremely complex process, many operating parameters affecting panel quality. It is a big challenge to...
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Feature selection approaches identify potential plasma metabolites in postmenopausal osteoporosis patients
IntroductionPostmenopausal women with osteoporosis (PMOP) are prone to fragility fractures. Osteoporosis is associated with alterations in the levels...
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Associations of longitudinal D-Dimer and Factor II on early trauma survival risk
BackgroundTrauma-induced coagulopathy (TIC) is a disorder that occurs in one-third of severely injured trauma patients, manifesting as increased...
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Clerodendrum inerme (L.) Gaertn.: a critical review on current progress in traditional uses, phytochemistry, pharmacological aspects and toxicity
Clerodendrum inerme (L.) Gaertn., commonly known as garden quinine, is a perennial shrub that belongs to the Lamiaceae family. It has been...
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CAMK2A supported tumor initiating cells of lung adenocarcinoma by upregulating SOX2 through EZH2 phosphorylation
Tumor initiating cells (TIC) of lung cancer are mainly induced by stress-related plasticity. Calcium/Calmodulin dependent protein kinase II alpha...
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Strategies for Enhancement of Transgene Expression
Expressing a foreign gene from an AT-rich organism in a GC-rich organism is difficult. To enhance the expression of heterologous genes in plants,... -
Cytotoxicity assay using a human pluripotent stem cell–derived cranial neural crest cell model
Cleft lip and palate are the most common congenital abnormalities that occur early in pregnancy. The majority of cranial mesenchyme is derived from...
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Calcium channel α2δ1 subunit is a functional marker and therapeutic target for tumor-initiating cells in non-small cell lung cancer
It is hypothesized that tumor-initiating cells (TICs) with stem cell-like properties constitute a sustaining force to drive tumor growth and renew...
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In vitro and in vivo biological control of the green mold using different bacteria in button mushroom cultivation
BackgroundAggressive biotype ( Trichoderma aggressivum f. aggressivum ) of green mold is one of the main biotic factors limiting button mushroom ( Agari...
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Miticidal effect of Guajava pyrifera L. against Suidasia pontifica Oudemans
The present study aims to assess the bioactivity of guava leaf extract (GLE) against Suidasia pontifica , a stored grain mite. The current study aimed...
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Erforschen der Aortenklappenstenose im mikrophysiologischen System
Calcific aortic valve disease results in stenosis and patient death if aortic valve (AV) is not replaced by prosthesis. Since conventional 2D valve...
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Functional properties of planktic microalgae determine their habitat selection
In this study, we aim to investigate how the functional properties of microalgae help to delineate the major groups of aquatic habitats. Using...
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Methanol as a co-substrate with CO2 enhances butyrate production in microbial electrosynthesis
AbstractMethanol is a promising feedstock for the bio-based economy as it can be derived from organic waste streams or produced electrochemically...