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Mesenchymal Stem Cell-based Scaffolds in Regenerative Medicine of Dental Diseases
Biomedical engineering breakthroughs and increased patient expectations and requests for more comprehensive care are propelling the field of...
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Emerging Role of Gut Microbiome in Cancer Immunotherapy
Current scientific advances have considerably added to our understanding of the complex association between the microbiome and cancer. Host and... -
Matrix metalloproteinase gene polymorphisms in chronic periodontitis: a case–control study in the Indian population
Chronic periodontitis (CP) is the common form of inflammatory oral disease. Matrix metalloproteinases (MMPs) play a pivotal role in the progression...
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Relationship of NLRP3 inflammasome with periodontal, endodontic and related systemic diseases
NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) is an inflammasome associated with oral and general health. There is a bidirectional...
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Advances in combined application of dental stem cells and small-molecule drugs in regenerative medicine
Teeth are a kind of masticatory organs of special histological origin, unique to vertebrates, playing an important role in chewing, esthetics, and...
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Investigating the relationship between the VNTR variant of the interleukin-1 receptor antagonist gene and coronary in-stent restenosis
ObjectiveThis study aimed to examine the association between the interleukin-1 receptor antagonist gene (IL-1RN) and coronary in-stent restenosis...
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Microbiota of Saliva: A Non-invasive Diagnostic Tool
Potential of salivary microbiota as a non-invasive diagnostic tool for various diseases are explained in the present review. Traditional diagnostic...
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Boric Acid Reverses Nicotine-Induced Cytokine Expressions of Human Gingival Fibroblasts
Nicotine, the major bioactive ingredient in tobacco, is a major risk factor for periodontal disease and destruction. Nicotine has been shown to...
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Systems Biology and Hospital-Associated Infections
Hospital-associated infections (HAIs) have become a major threat and lead to almost over 90,000 deaths globally per year. Advanced methods of... -
DNA Methylation and Histone Modification in Dental-derived Mesenchymal Stem Cells
AbstractEpigenetic regulation, mainly involving DNA methylation, histone modification, and noncoding RNAs (ncRNAs), is essential for the regulation...
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Genomic Tools in Clinical Epidemiology
The advent of high-throughput technologies, including next-generation sequencing (NGSs), is currently revolutionizing our understanding of several... -
Antibiofilm properties of cathelicidin LL-37: an in-depth review
Notwithstanding ceaseless endeavors toward develo** effective antibiofilm chemotherapeutics, biofilm-associated infections continue to be one of...
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An evaluation of the molecular mode of action of trans-resveratrol in the Porphyromonas gingivalis lipopolysaccharide challenged neuronal cell model
Porphyromonas gingivalis triggers a range of innate immune responses in the host that may contribute to the development of periodontitis and...
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Human Microbiome and Lifestyle Disorders
The human microbiome builds a multifaceted and dynamic ecosystem with the body that shapes the metabolic as well as immunological behavior of human... -
Selected Indian Medicinal and Aromatic Plants for Prophylactic Therapy
Ancient Indian medical practioners had extensive knowledge of medicinal properties of indigenous plants and used them to cure ailments Many of these... -
A Review on Microbial Species for Forensic Body Fluid Identification in Healthy and Diseased Humans
Microbial communities present in body fluids can assist in distinguishing between types of body fluids. Metagenomic studies have reported bacterial...
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Dental Pulp Stem Cells in Endodontics: Advances, Applications, and Challenges
Stem cells are clonogenic cells capable of self-renewal and multi-lineage differentiation. Since the first isolation of dental pulp stem cells... -
Metagenomic analysis reveals distinct changes in the gut microbiome of obese Chinese children
BackgroundThe prevalence of obese children in China is increasing, which poses a great challenge to public health. Gut microbes play an important...
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Interleukin-16 genetic polymorphisms in Guangxi Chinese with hepatitis B virus-related liver cirrhosis
BackgroundOur previous study has reported that interleukin-16 (IL-16) genetic polymorphisms are significantly related to chronic hepatitis B (CHB)...
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The Potential of miR-21 in Stem Cell Differentiation and its Application in Tissue Engineering and Regenerative Medicine
MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are two important types of non-coding RNAs that are not translated into protein. These...