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Rutaecarpine Protects Against Cigarette Smoke–Induced Chronic Obstructive Pulmonary Disease (COPD) in Rats
AbstractChronic obstructive pulmonary disease (COPD) is a chronic lung inflammatory disease that causes restricted airflow and breathing...
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Population Rearrangement of B Lymphocytes Expressing Chemokine Receptors in Patients with Chronic Obstructive Pulmonary Disease
Abstract —To date, there are no drugs that can prevent progressive destruction of lung tissue and small airway fibrosis in patients with chronic...
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Knockdown of circ_0006872 alleviates CSE-induced human bronchial epithelial cells injury in chronic obstructive pulmonary disease
Circular RNAs (circRNAs) have been reported to be related to the initiation and progression of chronic obstructive pulmonary disease (COPD) by...
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ceRNA Network Analysis Reveals Potential Key miRNAs and Target Genes in COVID-19-Related Chronic Obstructive Pulmonary Disease
The continued spread of SARS-CoV-2 has presented unprecedented obstacles to the worldwide public health system. Especially, individuals with chronic...
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The Effect of Glucocorticoids in Combination with Azithromycin or Theophylline on Cytokine Production by NK and NKT-Like Blood Cells of Patients with Chronic Obstructive Pulmonary Disease
AbstractChronic obstructive pulmonary disease (COPD) is characterized by reduced sensitivity of cells to the anti-inflammatory effects of...
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Novel drug delivery systems targeting oxidative stress in chronic obstructive pulmonary disease: a review
Oxidative stress is significantly involved in the pathogenesis and progression of chronic obstructive pulmonary disease (COPD). Combining antioxidant...
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Biological Influence of Pulmonary Disease Conditions Induced by Particulate Matter on Microfluidic Lung Chips
Particulate matter (PM10)-induced respiratory illnesses are difficult to investigate in trans-well culture systems. Microphysiological systems offer...
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Novel inhalation therapy in pulmonary fibrosis: principles, applications and prospects
Pulmonary fibrosis (PF) threatens millions of people worldwide with its irreversible progression. Although the underlying pathogenesis of PF is not...
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Nanomedicine Applied to Inflammatory and Infectious Pulmonary Diseases
Chronic pulmonary diseases often include inflammation in the upper or lower respiratory tract causing severe/extreme discomfort. To subside...
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miR-221-3p is upregulated in acute pulmonary embolism complicated with pulmonary hypertension and promotes pulmonary arterial smooth muscle cells proliferation and migration by inhibiting PTEN
Pulmonary arterial smooth muscle cells (PASMCs) functions are associated with the pathogenesis of pulmonary hypertension (PH) which is a...
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Nano-Based Therapies for Acute and Chronic Lung Diseases
Nanotechnology in medicine—known as nanomedicine—has opened a new era for accurate and precise diagnosis and treatment of pulmonary inflammatory...
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Ultra-processed food consumption and risk of chronic respiratory diseases mortality among adults: evidence from a prospective cohort study
PurposeThe purpose of the study was to determine the relationships between ultra-processed food (UPF) consumption and risk of mortality due to...
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Guardians Turned Culprits: NETosis and Its Influence on Pulmonary Fibrosis Development
Idiopathic pulmonary fibrosis (IPF) is a debilitating, life-threatening irreversible lung disease characterized by the excessive accumulation of...
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Extracellular vesicles in venous thromboembolism and pulmonary hypertension
Venous thromboembolism (VTE) is a multifactorial disease, and pulmonary hypertension (PH) is a serious condition characterized by pulmonary vascular...
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Nanomaterials-assisted gene editing and synthetic biology for optimizing the treatment of pulmonary diseases
The use of nanomaterials in gene editing and synthetic biology has emerged as a pivotal strategy in the pursuit of refined treatment methodologies...
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Tuberculosis: Cellular Understanding of Disease
Tuberculosis is undoubtedly a public health concern. An understanding of the cellular make-up of the disease can help in its mitigation by several...
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Pharmacokinetics of Nanoparticle Systems for Pulmonary Delivery
The introduction of nanotechnology in the pharmaceutical field has incited the attention of researchers to develop nanoparticle-based formulations to...
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Evaluation of Serum LECT2 and Sclerostin Levels in Patients Followed up for Obstructive Sleep Apnea
AbstractBackground: Obstructive sleep apnea (OSA) is characterized by recurrent apnea/hypopnea in the upper airways and oxygen desaturation...
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MAP3K19 Promotes the Progression of Tuberculosis-Induced Pulmonary Fibrosis Through Activation of the TGF-β/Smad2 Signaling Pathway
Tuberculosis-induced pulmonary fibrosis (PF) is a chronic, irreversible interstitial lung disease, which severely affects lung ventilation and air...
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Obesity: A Disease of Overnutrition
Obesity is a serious worldwide problem that is increasing in prevalence. Obesity results from increased energy intake from food exceeding what is...