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Quantitative analysis of fatty acids and vitamin E and total lipid profiling of dietary supplements from the German market
Certain polyunsaturated fatty acids with n-3 double bonds are essential nutrients for the human body and are part of the bilayer of cell membranes or...
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Development of a stable semi-continuous lipid production system of an oleaginous Chlamydomonas sp. mutant using multi-omics profiling
BackgroundMicroalgal lipid production has attracted global attention in next-generation biofuel research. Nitrogen starvation, which drastically...
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Deep profiling of plasmalogens by coupling the Paternò–Büchi derivatization with tandem mass spectrometry
Plasmalogens are a special class of glycerophospholipids characterized by a vinyl ether bond (-C = C-O-) at the sn -1 position of the glycerol...
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Lipid biomarker profiling of adult Brugia malayi using mass spectrometry detection
In this article, we first reported the lipid profile of adult Brugia malayi using ultra-performance liquid chromatography electrospray ionization...
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Transcriptomic profiling of an evolved Yarrowia lipolytica strain: tackling hexanoic acid fermentation to increase lipid production from short-chain fatty acids
BackgroundShort-chain fatty acids (SCFAs) are cost-effective carbon sources for an affordable production of lipids. Hexanoic acid, the acid with the...
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In situ droplet-based on-tissue chemical derivatization for lipid isomer characterization using LESA
In this work, we present an in situ droplet-based derivatization method for fast tissue lipid profiling at multiple isomer levels. On-tissue...
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Comprehensive lipidomic profiling by plasma separation cards
Large-scale lipidomic analyses have been limited by the cost and accessibility of traditional venipuncture sampling. Microsampling techniques offer a...
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Lipidomic Profiling to Assess the Freshness of Stored Cabbage
The quantitative freshness assessment method for vegetables is desired to upgrade the quality management system in agricultural distribution chain....
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Differential lipid analysis of oxaliplatin-sensitive and resistant HCT116 cells reveals different levels of drug-induced lipid droplet formation
Lipid droplets (LDs) are intracellular storage vesicles composed of a neutral lipid core surrounded by a glycerophospholipid membrane. LD...
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Untargeted hair lipidomics: comprehensive evaluation of the hair-specific lipid signature and considerations for retrospective analysis
Lipidomics investigates the composition and function of lipids, typically employing blood or tissue samples as the primary study matrices. Hair has...
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Lipidomic profiling of Indonesian coffee to determine its geographical origin by LC–MS/MS
Lipids are biochemical compounds that are substantially present in coffee beans. However, lipids in coffee have not been comprehensively studied thus...
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Blood serum lipid profiling may improve the management of recurrent miscarriage: a combination of machine learning of mid-infrared spectra and biochemical assays
The present article is focused on develo** and validating an efficient, credible, minimally invasive technique based on spectral signatures of...
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Comprehensive Targeted Lipidomic Profiling for Research and Clinical Applications
Mass spectrometry remains one of the gold standard approaches in examining the lipidome in biological samples. Recently, advancements in... -
Leveraging the use of ionic liquid capillary columns and GC×GC-MS for fatty acid profiling in human colostrum samples
Lipids in human colostrum provide the majority of energy intake and essential fatty acids for develo** infants. The fatty acid composition of human...
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Lipidomic Profiling of Argania spinosa L. (Skeels) Following Drought Stress
Argan tree is frequently constrained by environmental stresses, especially drought. Lipids play crucial roles in stress adaptation, but lipidomic...
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Nitrogen starvation causes lipid remodeling in Rhodotorula toruloides
BackgroundThe oleaginous yeast Rhodotorula toruloides is a promising chassis organism for the biomanufacturing of value-added bioproducts. It can...
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Global signal peptide profiling reveals principles of selective Sec61 inhibition
Cotransins target the Sec61 translocon and inhibit the biogenesis of an undefined subset of secretory and membrane proteins. Remarkably, cotransin...
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Analysis of lipid composition and characterization of acyl steryl glycosides in rose petals by using nontargeted LC/MS
Edible roses are rich in bioactive metabolites including lipids and they are widely used in food and traditional medicine. The phytochemicals present...
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Characterization of the cellular lipid composition during SARS-CoV-2 infection
Emerging and re-emerging zoonotic viral diseases continue to significantly impact public health. Of particular interest are enveloped viruses (e.g.,...
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Development of a high-performance thin-layer chromatography-based method for targeted glycerolipidome profiling of microalgae
The conditionally essential very-long-chain polyunsaturated fatty acids (VLC-PUFAs), such as eicosapentaenoic acid (EPA, C20:5 n-3), play a vital...