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Untargeted metabolite profiling of serum in rats exposed to pyrraline
Pyrraline, one of advanced glycation end-products, is formed in advanced Maillard reactions. It was reported that the presence of pyrraline was...
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Porphyrin-lipid stabilized paclitaxel nanoemulsion for combined photodynamic therapy and chemotherapy
BackgroundPorphyrin-lipids are versatile building blocks that enable cancer theranostics and have been applied to create several multimodal...
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Determination of Total Liver Glutathione and Plasma Malondialdehyde Concentrations
Probiotics are recommended to improve human and animal health; however, the assessment of safety aspects of probiotics is an important concern to...
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Application of untargeted volatile profiling in inflammatory bowel disease research
Inflammatory bowel disease (IBD) diagnosis depends on criteria based on histological, endoscopic, radiological, and clinical results. These studies...
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Phenolics profiling and biological activities of different solvent extracts from aerial parts of wild thyme (Thymus vulgaris L.)
The current research work appraises the variation in antioxidant, antibacterial and cytotoxic potential of thyme extracts in relation to different...
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AP2/ERF and R2R3-MYB family transcription factors: potential associations between temperature stress and lipid metabolism in Auxenochlorella protothecoides
BackgroundBoth APETALA2/Ethylene Responsive Factor (AP2/ERF) superfamily and R2R3-MYB family were from one of the largest diverse families of...
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Bioactivity profiling of the extremolyte ectoine as a promising protectant and its heterologous production
Ectoine is a compatible solutes that is diffusely dispersed in bacteria and archaea. It plays a significant role as protectant against various...
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Lipidomic Markers of Tumor Progress in Breast Cancer Patients
Abstract —Research of cancer progression mechanisms and their impact on metabolism of tumor cells and tumor microenvironment cells is an important...
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Amino acid profiling and structural characterization of sorghum protein concentrates using enzyme liquefaction
Sorghum protein concentrate was produced from sorghum flour utilizing α-amylase treatment for starch liquefaction. A central composite design was...
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Semi-coordination Cu–O bond on a copper complex featuring O,O-donor ligand as potential antibacterial agent: green synthesis, characterization, DFT, in-silico ADMET profiling and molecular docking studies
The synthesis of 2-((5-methyl-pyridin-2-yl)amino)acetic acid ( MPAA ) and its copper complex ( Cu-MPAA ) has been performed. The new ligand, MPAA , was...
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Ferocactus herrerae Fruits: Nutritional Significance, Phytochemical Profiling, and Biological Potentials
The current study reports for the first time the nutritional, fruit volatiles, phytochemical, and biological characteristics of Ferocactus herrerae ...
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Combined analysis of the metabolome and transcriptome provides insight into seed oil accumulation in soybean
BackgroundSoybean ( Glycine max (L.) Merr) is an important source of human food, animal feed, and bio-energy. Although the genetic network of lipid...
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Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP
Metabolic alterations in cancer precipitate in associated dependencies that can be therapeutically exploited. To meet this goal, natural...
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Facile Fabrication of Nanoformulated Cinnamomum glaucescens Essential Oil as a Novel Green Strategy to Boost Potency Against Food Borne Fungi, Aflatoxin Synthesis, and Lipid Oxidation
The study presents chitosan nanoemulsion encapsulating Cinnamomum glaucescens essential oil (CGEO) as a novel green preservative against food born...
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Probing the microbial diversity and probiotic candidates from Pakistani foods: isolation, characterization, and functional profiling
Probiotics represent beneficial living microorganisms that confer physiological, nutritional, and functional advantages to human health, holding...
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Lipid composition of the cancer cell membrane
Cancer cell possesses numerous adaptations to resist the immune system response and chemotherapy. One of the most significant properties of the...
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Chemical Derivatization to Enhance Capillary Electrophoresis Mass Spectrometric Analysis of Acidic Metabolites in Mammalian Cells
The simultaneous analysis of cationic and anionic metabolites using capillary electrophoresis–mass spectrometry (CE–MS) has been considered...
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Potential of Algal Biomass and Their Cultivation for Biofuels Production as Plausible Bio-resource for Economic Sustainability
Depletion of conventional energy resources necessitates the exploration of new alternative raw materials for sustainable biofuel production to...
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Lipidomics Analysis of Different Marine Fish Oils Using Untargeted Liquid Chromatography–Orbitrap High-Resolution Mass Spectrometry and Chemometrics
Marine fish oils (MFOs) have been known for their nutritional compounds, which benefit human health. MFOs contain various lipids which play an...
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Non-targeted Profiling of Sea Buckthorn Fruit Oil Fingerprints from 3 Regions and Study on Its Antioxidant Activity
This study investigated the chemical and volatile characteristics of sea buckthorn fruits from three different regions in China. The chemical...
