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COVID-19: Molecular Pathogenesis and Prospective Therapeutic Interventions
COVID-19 is a catastrophe taking a massive toll on humanity across the world. It is a highly transmissible airborne infection. The pathogen...
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Transforming microbial pigment into therapeutic revelation: extraction and characterization of pyocyanin from Pseudomonas aeruginosa and its therapeutic potential as an antibacterial and anticancer agent
BackgroundThe objectives of the current study were to extract pyocyanin from Pseudomonas aeruginosa clinical isolates, characterize its chemical...
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A highly therapeutic and selective delivery system for curcumin based on nanocellulose and folic acid
Curcumin (CUR) is an emerging natural agent for cancer therapy. However, the low therapeutic efficacy and weak selectivity of CUR still severely...
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Pharmacological Insights into Morin: Therapeutic Applications and Future Perspectives
Morin is a yellow bioactive pigment compound that is abundantly found in various fruits and plants. Similar to other flavonoid derivatives, morin has...
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Development of an on-site therapeutic drug monitoring method using a portable spectrometer
We report on the development of an on-site therapeutic drug monitoring (TDM) method for vancomycin (VCM) utilizing a portable spectrometer and...
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Design of point-of-care electrochemical sensor for therapeutic drug monitoring of ofloxacin in biological fluids
A disposable screen-printed sensor has been crafted specifically for therapeutic drug monitoring purposes, particularly for detecting ofloxacin in...
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Natural ursolic acid based self-therapeutic polymer as nanocarrier to deliver natural resveratrol for natural therapy of acute kidney injury
Acute kidney injury (AKI) is a common kidney disease associated with excessive reactive oxygen species (ROS). Unfortunately, due to the low kidney...
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Therapeutic Potential of Rhodium Complexes
Until recently, rhodium was one of the neglected metals towards drug development. However, research in the recent past witnessed the development of...
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Extracellular vesicles: emerging roles, biomarkers and therapeutic strategies in fibrotic diseases
Extracellular vesicles (EVs), a cluster of cell-secreted lipid bilayer nanoscale particles, universally exist in body fluids, as well as cell and...
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Unveiling Potential Targeted Therapeutic Opportunities for Co-Overexpressed Targeting Protein for Xklp2 and Aurora-A Kinase in Lung Adenocarcinoma
Lung adenocarcinoma (LUAD) is one of the most prevalent and leading causes of cancer deaths globally, with limited diagnostic and clinically...
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Scutellarin: Bioactivities, Pharmacology, and Development as Promising Therapeutic Agents and Nutraceuticals
Scutellarin is a polyphenolic flavone with a characteristic C7-glucuronide substituent. It is widely distributed in nature, particularly in the mint...
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Adjuvant Therapeutic Effect of Cinnamon on Diabetes Mellitus
Compared to traditional medicine, herbal medicines have a long history of treating and preventing diseases, including diabetes. Cinnamon has been...
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A multi-parameter-induced activation of gas therapeutic platform to remarkably amplify photodynamic therapy efficacy
Gas therapy (GT) combined with photodynamic therapy (PDT) is an effective strategy to compensate for the PDT limitation caused by the hypoxic tumor...
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Targeting Ferroptosis as a Therapeutic Implication in Lung Cancer Treatment by a Novel Naphthoquinone Inducer: Juglone
Lung cancer has garnered significant global attention as a result of its escalating rates of mortality and morbidity, necessitating focused...
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The Therapeutic Antibody Profiler for Computational Developability Assessment
The need to consider an antibody’s “developability” (immunogenicity, solubility, specificity, stability, manufacturability, and storability) is now...
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Distribution, biosynthesis and therapeutic potential of lignans
Lignans have long been known for their abundant therapeutic properties due to their polyphenolic structure. Linseed is the richest plant source of...
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SP110 Could be Used as a Potential Predictive and Therapeutic Biomarker for Oral Cancer
The morbidity of oral squamous cell carcinoma (OSCC) has been rising year after year, making it a major global health issue. But the molecular...
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Extension of recommended cross section database for production of therapeutic isotopes
Radionuclide-based diagnostics and therapy require proper selection of production nuclear reaction based on knowledge of the production excitation...
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Nanostructures and biomaterials based on silk polymer for medical diagnostic and therapeutic applications
Today, SF is a natural polymer with unique features, such as excellent mechanical properties, biocompatibility, biodegradability, and low toxicity,...
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Selective and Site-Specific Incorporation of Nonstandard Amino Acids Within Proteins for Therapeutic Applications
The incorporation of nonstandard amino acids (nsAAs) within protein sequences has broadened the chemical functionalities available for use in the...