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Synthesis and pharmacological activities of Schiff bases with some transition metal complexes: a review
Schiff bases transition metal complexes have received significant attentions in the scientific community for their versatile applications. The...
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Metal/Metal Oxide Nanocarriers for the Delivery of Phytoconstituents
Inorganic nanoparticles like metal and metal oxide nanoparticles are one of the best theranostics particles that within the nanosize range show... -
Classification of Metal-Based Anticancer Chemotherapeutic Agents
3d metal-based chemotherapeutic agents are considered as the promising viable options for the treatment of solid malignancies as compared to... -
Advanced Drug Delivery Strategies for Metal-Based Anticancer Drugs
Metal-based anticancer drugs, such as platinum complexes (e.g., cisplatin, carboplatin, and oxaliplatin), have demonstrated remarkable efficacy in... -
Renal hypoxia–HIF–PHD–EPO signaling in transition metal nephrotoxicity: friend or foe?
The kidney is the main organ that senses changes in systemic oxygen tension, but it is also the key detoxification, transit and excretion site of...
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Progress and Future Projections in Metal-Based Polymeric Anticancer Compounds
Metal-based polymeric compounds have emerged as promising agents in the field of anticancer therapeutics due to their unique properties and... -
Endoplasmic Reticulum (ER)-Targeted Metal-Based Anticancer Chemotherapeutic Agents
In the recent past, an emerging “hot” area of research in medicinal inorganic chemistry that has attracted considerable attention is the design of... -
Recent Advances in Targeting Transition Metals (Copper, Iron, and Zinc) in Alzheimer’s Disease
Changes in the transition metal homeostasis in the brain are closely linked with Alzheimer’s disease (AD), including intraneuronal iron accumulation...
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Connecting copper and cancer: from transition metal signalling to metalloplasia
Copper is an essential nutrient whose redox properties make it both beneficial and toxic to the cell. Recent progress in studying transition metal...
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Fortilin as a Biomarker in Toxicity
Fortilin, the multifunctional protein, also known as translationally controlled tumor protein (TCTP), presents in most eukaryotic organisms. It is... -
Combined Toxicity of Metal Nanoparticles: Comparison of Individual and Mixture Particles Effect
Toxicity of metal nanoparticles (NPs) are closely associated with increasing intracellular reactive oxygen species (ROS) and the levels of... -
Ceria nanoparticles: biomedical applications and toxicity
Ceria nanoparticles (CeO 2 NPs) have become popular materials in biomedical and industrial fields due to their potential applications in...
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One-Dimensional Semiconducting Nanomaterials: Toxicity and Clinical Applications
One-dimensional (1D) semiconductors have recently triggered intense research in diverse areas. These materials have already made substantial strides... -
The Effects of Fisetin and Curcumin on Oxidative Damage Caused by Transition Metals in Neurodegenerative Diseases
Neurodegenerative diseases pose a significant health challenge for the elderly. The escalating presence of toxic metals and chemicals in the...
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Optical Chemosensors Synthesis and Appplication for Trace Level Metal Ions Detection in Aqueous Media: A Review
In recent years, the development of optical chemosensors for the sensitive and selective detection of trace level metal ions in aqueous media has...
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Metal Chelators as a Potential Therapeutic Agent for Alzheimer’s Disease
Alzheimer’s disease (AD) is a neurological condition that causes behavioural abnormalities and a progressive decline in intellectual abilities.... -
Ratiometric Fluorescence and Chromogenic Probe for Trace Detection of Selected Transition Metals
The design and development of a fluorescence sensor aimed at detecting and quantifying trace amounts of toxic transition metal ions within...
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Biochemical Mechanistic Pathway of Cell Death Induced by Metal-Based Chemotherapeutic Agents
A large plethora of metal complexes that could act as potent anticancer chemotherapeutic agents have been designed and developed in the recent past... -
Metal nanoparticles as a potential technique for the diagnosis and treatment of gastrointestinal cancer: a comprehensive review
Gastrointestinal (GI) cancer is a major health problem worldwide, and current diagnostic and therapeutic approaches are often inadequate. Various...
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Assessment of toxicity and genotoxic safety profile of novel fisetin ruthenium-p-cymene complex in mice
Throughout the last decades flavonoids have been considered as a powerful bioactive molecule. Complexation of these flavonoids with metal ions...