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Sympathetic innervation of human and porcine spleens: implications for between species variation in function
BackgroundThe vagus nerve affects innate immune responses by activating spleen-projecting sympathetic neurons, which modulate leukocyte function....
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The tumor-nerve circuit in breast cancer
It is well established that innervation is one of the updated hallmarks of cancer and that psychological stress promotes the initiation and...
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Nerves in cancer
The contribution of nerves to the pathogenesis of malignancies has emerged as an important component of the tumour microenvironment. Recent studies...
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Cerebral Vasoreactivity
Cerebral blood flow is mainly regulated by two mechanisms: cerebral autoregulation and neurovascular coupling (NVC). Cerebral autoregulation...
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Neurotransmitters
The activities of vasculature are regulated by neurotransmitters released from the nerve terminals in the wall of the blood vessels, which include...
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Splenic stromal niches in homeostasis and immunity
The spleen is a gatekeeper of systemic immunity where immune responses against blood-borne pathogens are initiated and sustained. Non-haematopoietic...
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Adrenergic Modulation of Hematopoiesis
Hematopoiesis produce every day billions of blood cells and takes place in the bone marrow (BM) by the proliferation and differentiation of...
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Regulation of the Effective Circulating Volume and the Sodium Balance
As mentioned in Chap. 1 , the kidney plays a key role in maintaining the composition and volume of extracellular...
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Pulmonary Vasoreactivity
Pulmonary circulation is characterized by low intravascular arterial pressure and low vascular resistance. As compared with those of systemic...
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Glymphatic System
The brain is one of the most metabolically active organs in the body, and continuous removal of excess fluid and waste products is critical for...
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Theoretical analysis of wake/sleep changes in brain solute transport suggests a flow of interstitial fluid
Clearance of protein waste products from the brain is accomplished by a combination of advection and diffusion in cerebrospinal fluid (CSF) and...
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Hematopoietic Stem Cells and Their Bone Marrow Niches
Hematopoietic stem cells (HSCs) are maintained in the bone marrow microenvironment, also known as the niche, that regulates their proliferation,...
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Cardiovascular Responses to Exercise in Diabetes
Individuals with diabetes are commonly encouraged to participate in regular exercise or physical activity to help manage their disease and protect...
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Neural regulation of the contractility of nutrient artery in the guinea pig tibia
Nutrient arteries provide the endosteal blood supply to maintain bone remodelling and energy metabolism. Here, we investigated the distribution and...
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Coronary Vasoreactivity
The heart has the highest O2 consumption rate of all of the organs in the body. The resting left ventricle extracts ~70–80% of the O2 delivered by...
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Rhombomere 11 r11
Starting with this chapter, the description of the neuromeres (in caudocranial order rhombomeres 11-1, isthmus, m1/m2) follows. Rhombomere 11 is the...
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Harm of circadian misalignment to the hearts of the adolescent wistar rats
PurposeThe purpose of this study was to observe the harm of circadian misalignment (CM), caused by an inverted photoperiod (IP), on the hearts of the...
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Electronic Cigarette Va** with Nicotine Causes Increased Thrombogenicity and Impaired Microvascular Function in Healthy Volunteers: A Randomised Clinical Trial
Electronic cigarette (EC) va** is increasingly popular, despite growing evidence of adverse health effects. To further evaluate the impact of EC...
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Autonomic Function and Electroacupuncture
Effectiveness of acupuncture in regulating suboptimal autonomic function and its mechanisms are investigated for several decades by the scientific...