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Comparison of the Effects of KE and AED Peptides on Functional Activity of Human Skin Fibroblasts during Their Replicative Aging
We studied the effect of KE and AED peptides on the expression of sirtuin-1, sirtuin-6, collagen I, cytokines (IL-1, TGF-β), and transcription factor...
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MicroRNA expression profiling of cerebrospinal fluid/serum exosomes in children with human herpesvirus 6-associated encephalitis/encephalopathy by high-throughput sequencing
Primary human herpesvirus 6 (HHV-6) infection is sometimes accompanied by acute encephalopathy with reduced subcortical diffusion (AED) in...
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Anti-epileptic drugs and prostate cancer-specific mortality compared to non-users of anti-epileptic drugs in the Finnish Randomized Study of Screening for Prostate Cancer
BackgroundDrugs with histone deacetylase inhibitory (HDACi) properties have shown to decrease prostate cancer (PCa) cell growth in vitro.
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Micronutrients and Epilepsy
Epilepsy is a devastating neurological disorder that affects millions of people worldwide. It creates a substantial financial, emotional, and...
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Feasibility of Using Oral Fluid for Therapeutic Drug Monitoring of Antiepileptic Drugs
Therapeutic drug monitoring (TDM) of antiepileptic drugs (AED) using blood is well established but limited by its invasiveness, accessibility, cost,...
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Resolvin D1 treatment on goblet cell mucin and immune responses in the chronic allergic eye disease (AED) model
Severe, chronic eye allergy is an understudied, vision-threatening condition. Treatments remain limited. We used a mouse model of severe allergic eye...
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Chemogenetic Seizure Control with Clozapine and the Novel Ligand JHU37160 Outperforms the Effects of Levetiracetam in the Intrahippocampal Kainic Acid Mouse Model
Expression of inhibitory designer receptors exclusively activated by designer drugs (DREADDs) on excitatory hippocampal neurons in the hippocampus...
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Effectiveness of a multimodal intervention to improve blood culture collection in an adult emergency department
We investigated the impact of a multimodal intervention to improve the compliance of BC collections as a composite outcome, taking into account both...
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C. elegans as a Potential Model for Acute Seizure-Like Activity
Conventional rodent models have provided invaluable tools for the discovery and characterization of antiepileptic drugs (AEDs). Nevertheless, around...
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Psychotic Disorders in Epilepsy: Do They Differ from Primary Psychosis?
Any attempt to compare the definitions of symptoms listed for “primary psychoses” with those adopted in studies of psychoses in patients with...
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Clinical and diagnostic characteristics of Hashimoto’s encephalopathy: a single-center, retrospective study
Background and purposeDiagnosing Hashimoto’s encephalopathy (HE) is challenging. In contrast to other types of autoimmune encephalitis, HE shows an...
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The Role of Neurotransmitters in Epileptogenesis: Focus on GABA and Glutamate
Epileptic seizures are frequently referred to as a brief development of a number of signs and symptoms resulting from extreme or synchronized...
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Recommendations for the treatment of epilepsy in adult and pediatric patients in Belgium: 2020 update
To guide health care professionals in Belgium in selecting the appropriate antiepileptic drugs (AEDs) for their epilepsy patients, a group of Belgian...
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A highlight on carbamazepine-induced adverse drug reactions in Saudi Arabia: a retrospective medical records-based study
The link between human leukocyte antigen (HLA) alleles and carbamazepine-induced cutaneous, respiratory, and gastrointestinal adverse drug reactions...
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Psychotropic and anti-epileptic drug use, before and after surgery, among patients with low-grade glioma: a nationwide matched cohort study
BackgroundLow-grade glioma (LGG) is a relatively rare type of brain tumour. The use of antidepressant, sedative and anti-epileptic drugs can reflect...
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Clinical features of nine cases of leucine-rich glioma inactivated 1 protein antibody-associated encephalitis
To investigate clinical features of leucine-rich glioma inactivated 1 protein (LGI1) antibody-associated autoimmune encephalitis (AE). The clinical...
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Detection of ventricular arrhythmia using hybrid time–frequency-based features and deep neural network
Sudden cardiac death (SCD) is a major cause of death among patients with heart diseases. It occurs mainly due to ventricular tachyarrhythmia (VTA)...
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COVID-19 and antiepileptic drugs: an approach to guide practices when nirmatrelvir/ritonavir is co-prescribed
Management and dose adjustment are a major concern for clinicians in the absence of specific clinical outcome data for patients on antiepileptic...
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Epilepsy in Angelman’s Syndrome
Objectives . To study the neurological status, clinical/EEG patterns, neuroimaging, and the course of epilepsy in children with genetically confirmed...
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Implications of BCRP modulation on PTZ-induced seizures in mice: Role of ko143 and metformin as adjuvants to lamotrigine
Blood–brain barrier (BBB) efflux transporters' overexpression hinders antiepileptic drug brain entry. Breast cancer resistance protein (BCRP) is a...
