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Mitochondrial Involvement in Brain Function and Dysfunction: Relevance to Aging, Neurodegenerative Disorders and Longevity
It is becoming increasingly evident that the mitochondrial genome may play a key role in neurodegenerative diseases. Mitochondrial dysfunction is...
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Comparison of the Protection against Neuronal Injury by Hypothalamic Peptides and by Dexamethasone
The comparative study has been carried out on hypothalamic neurohormone (proline-rich polypeptides-PRP) and synthetic glucocorticoid dexamethasone...
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Stress proteins of 70 kDa in chronically exercised skeletal muscle
Skeletal muscle fibres of untrained animals experience a stress response following exercise. This study was aimed at investigating whether chronic...
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Cloning of the chaperonin t-complex polypeptide 1 gene from Schistosoma mansoni and studies of its expression levels under heat shock and oxidative stress
The protein TCP-1 (t-complex polypeptide 1) is a subunit of the hetero-oligomeric complex CCT (chaperonin containing TCP-1) present in the...
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CAP43
Nickel (Ni) compounds have been implicated in elevating the incidence of lung and nasal cancers in numerous epidemiological studies of nickel...
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Probing the relation between protein structure and intrinsic tryptophan fluorescence using superrepressor mutants of thetrp repressor
The wavelength dependence of the intrinsic tryptophan fluorescence lifetime of a series of mutants of the trp repressor protein was characterized in...
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Does stimulation of NaCl secretion in in vitro perfused rectal gland tubules of Squalus acanthias increase membrane capacitance?
NaCl secretion in rectal gland tubules (RGT) of Squalus acanthias requires the activation of Cl – channels in the luminal membrane. The RGT and its...
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Ion-specific protein destabilization of the contractile proteins of cardiac muscle fibers
We investigated the inhibitory effects of increased salt concentrations on maximal calcium-activated force ( F max ) of rabbit cardiac papillary...
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A History of Proteolipids: A Personal Memoir
This review is a personal memoir of the history of proteolipids and is limited to aspects of the field with which the author has been involved in one...
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Heat shock protein 70 in the retina of Xenopus laevis, in vivo and in vitro: effect of metabolic stress
We utilized the frog eyecup as an in vitro model to compare heat-shock protein 70 (hsp70) synthesis in untreated retinas and in hyperthermia-,...
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Differential distribution of the mitochondrial heat-shock protein 60 in rat gastrointestinal tract
Immunohistochemical studies on various parts of the rat gastrointestinal tract by means of an antibody against the mitochondrial chaperonin,...
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Cellular Responses to Stress
Since the evolution of the cellular phenotype, prokaryotic and eukaryotic cells have had to cope with adverse changes in their environment. Although...
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Heat Shock Regulation
The heat shock or stress response of Escherichia coli has evolved in order to detect and deal with the presence of unfolded, misfolded, damaged or...