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Ceruletide and Alpha-1 Antitrypsin as a Novel Combination Therapy for Ischemic Stroke
Ischemic stroke is a primary cause of morbidity and mortality worldwide. Beyond the approved thrombolytic therapies, there is no effective treatment...
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Dynamic Changes in the Estimated Glomerular Filtration Rate Predict All-Cause Mortality After Intravenous Thrombolysis in Stroke Patients
Little is known about the prognostic value of the estimated glomerular filtration rate (eGFR) and the effect of dynamic changes in the eGFR on...
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Hemorrhagic Transformation After Tissue Plasminogen Activator Treatment in Acute Ischemic Stroke
Hemorrhagic transformation (HT) is a common complication after thrombolysis with recombinant tissue-type plasminogen activator (rt-PA) in ischemic...
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Extracellular Vesicle Application as a Novel Therapeutic Strategy for Ischemic Stroke
Ischemic stroke (IS) accounts for most of the cases of stroke onset, and due to short therapeutic time window for thrombolysis and numerous limited...
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Progress of nanomaterials in the treatment of thrombus
Thrombus has long been the major contributor of death and disability because it can cause adverse effects to varying degrees on the body, resulting...
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Carotid artery stenting during endovascular thrombectomy for acute ischemic stroke with tandem occlusion: the Italian Registry of Endovascular Treatment in Acute Stroke
PurposeThe management of tandem extracranial internal carotid artery and intracranial large vessel occlusion during endovascular thrombectomy (EVT)...
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Retrovirus-Mediated Transfection of the Tissue-type Plasminogen Activator Gene Results in Increased Thrombolysis of Blood Clots
Tissue-type plasminogen activator (tPA) is involved in the lysis of blood clots. In this study, we attempted to target thrombolysis and enhance blood...
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Prognostic Value of Venous Outflow Profiles on Multiphase CT Angiography for the Patients with Acute Ischemic Stroke After Endovascular Thrombectomy
To evaluate the prognostic value of venous outflow (VO) profiles evaluated on multiphase CTA (mCTA) for the patients with acute ischemic stroke (AIS)...
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Sex Differences in the Evaluation and Treatment of Stroke
There are differences in the prevalence and strength of risk factors in women, along with sex-specific risk factors such as pregnancy. Women have a... -
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Revolutionizing Stroke Care: Nanotechnology-Based Brain Delivery as a Novel Paradigm for Treatment and Diagnosis
Stroke, a severe medical condition arising from abnormalities in the coagulation-fibrinolysis cycle and metabolic processes, results in brain cell...
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Neutrophil extracellular traps correlate with severity and prognosis in patients with ischemic stroke: a systematic review and meta-analysis
Background and objectiveA correlation between neutrophil extracellular traps (NETs) and ischemic stroke (IS) has been hypothesized, but the results...
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Short-term glycemic variability and hemorrhagic transformation after successful endovascular thrombectomy
BackgroundGlycemic variability (GV) is a risk factor for poor outcomes after ischemic stroke. However, its effect on hemorrhagic transformation after...
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D-Dimer Levels, Stroke, and Critical Care
Biomarkers are important tools in medical decision-making. D-Dimer levels show diagnostic and promising prognostic implications in several diseases... -
Symptomatic intracranial hemorrhage mediates the association between eosinophils and 90-day outcomes after mechanical thrombectomy for acute ischemic stroke
BackgroundDecreased eosinophil level is associated with poor outcomes after mechanical thrombectomy in patients with acute ischemic stroke (AIS), but...
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Deciphering the Role of Nanomedicines for the Treatment of Ischemic Stroke
Ischemic stroke (IS) affects 15 million people globally which leads to death or disability. Currently, Tissue plasminogen activator (tPA) is the only... -
Cerebellar Stroke
Cerebellar stroke consists of cerebellar infarctionInfarction and hemorrhageHemorrhage. The two entities have similar symptoms and signs depending on... -
Morphological predictors of neurological deterioration in patients with acute isolated pontine infarct
ObjectiveTo investigate morphological predictors of neurological deterioration (ND) in patients with acute isolated pontine infarct.
Methods ...