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Off-label tenecteplase use in spinal cord ischemia

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Fig. 1

Data Availability

All data relevant to the studyare included in the article or uploaded as supplementaryinformation.

References

  1. Almutlaq A, Alkhalifa A, Bereznyakova O (2022) Extended Window Thrombolysis in Acute Spinal Cord Ischemia. Can J Neurol Sci 49(3):465-466. https://doi.org/10.1017/cjn.2021.142

  2. Berge E, Whiteley W, Audebert H, De Marchis GM, Fonseca AC, Padiglioni C et al (2021) European stroke organisation (ESO) guidelines on intravenous thrombolysis for acute ischaemic stroke. Eur Stroke J 6(1):1–11. https://doi.org/10.1177/2396987321989865

    Article  Google Scholar 

  3. Dong Y, Sui Y, Cheng X, Wang DZ (2022) Is tenecteplase ready to replace alteplase to treat acute ischaemic stroke? The knowns and unknowns. Stroke Vasc Neurol 7(1):1–5. https://doi.org/10.1136/svn-2021-001321

    Article  CAS  PubMed  Google Scholar 

  4. Dorodnicov E, Gelfand A, Milo R (2017) Acute spinal cord ischemia treated with intravenous thrombolysis. J Neurologic Sci 381: 410. https://doi.org/10.1016/j.jns.2017.08.3370

  5. Etgen T, Höcherl C (2016) Repeated early thrombolysis in cervical spinal cord ischemia. J Thromb Thrombolysis. 42(1):142-145. https://doi.org/10.1007/s11239-015-1332-1

  6. Focke JK, Seitz RJ (2021) Reversal of Acute Spinal Cord Ischemia by Intravenous Thrombolysis. Neurol Clin Pract 11(6):e975-e976. https://doi.org/10.1212/cpj.0000000000001097

  7. Haynes J, Shapiro M, Raz E, Czeisler B, Nossek E (2021) Intra-arterial thrombolytic therapy for acute anterior spinal artery stroke. J Clin Neurosci 84:102-105. https://doi.org/10.1016/j.jocn.2020.11.035

  8. Jankovic J, Rey Bataillard V, Mercier N, Bonvin C, Michel P (2019) Acute ischemic myelopathy treated with intravenous thrombolysis: Four new cases and literature review. Int J Stroke 14(9):893-897. https://doi.org/10.1177/1747493019851289

  9. Koch M, Sepp D, Prothmann S, Poppert H, Seifert CL (2016) Systemic thrombolysis in anterior spinal artery syndrome: what has to be considered? J Thromb Thrombolysis 41(3):511-513. https://doi.org/10.1007/s11239-015-1281-8

  10. Lawson EC, Hu R, Silver M, Greene JG (2021) Administration of Recombinant Tissue Plasminogen Activator for Sulcal Artery Syndrome. Neurol Clin Pract 11(6):e901-e903. https://doi.org/10.1212/cpj.0000000000000995

  11. Lee K, Strozyk D, Rahman C, Lee LK, Fernandes EM, Claassen J, et al (2010) Acute spinal cord ischemia: treatment with intravenous and intra-arterial thrombolysis, hyperbaric oxygen and hypothermia. Cerebrovasc Dis 29(1):95-98. https://doi.org/10.1159/000259618

  12. Müller KI, Steffensen LH, Johnsen SH (2012) Thrombolysis in anterior spinal artery syndrome. BMJ Case Rep. 2012:bcr2012006862. https://doi.org/10.1136/bcr-2012-006862

  13. Restrepo L, Guttin JF (2006) Acute spinal cord ischemia during aortography treated with intravenous thrombolytic therapy. Tex Heart Inst J 33(1):74-77. PubMed PMID: 16572877; PubMed Central PMCID: PMC1413592.

  14. Warach SJ, Dula AN, Milling TJ (2020) Tenecteplase thrombolysis for acute ischemic stroke. Stroke 51(11):3440–3451. https://doi.org/10.1161/STROKEAHA.120.029749

    Article  PubMed  PubMed Central  Google Scholar 

  15. Wiszniewska M, Harat M (2017) The positive effect of combined treatment with thrombolysis and neurosurgery for cervical myelopathy due to anterior spinal artery thrombosis. Adv Psychiatry Neurol/Postepy Psychiatrii i Neurologii 26: 270–274. https://doi.org/10.5114/ppn.2017.72439

  16. **ao M, Huang X (2022) Anterior spinal artery syndrome, intravenous alteplase or not. Acta Neurol Belg 122(1):235-237. https://doi.org/10.1007/s13760-021-01802-2

  17. Zalewski NL (2021) Vascular myelopathies. Continuum (Minneap Minn) 27(1):30–61. https://doi.org/10.1212/CON.0000000000000905

    Article  PubMed  Google Scholar 

  18. Zalewski NL, Rabinstein AA, Krecke KN, Brown RD, Wijdicks EFM, Weinshenker BG et al (2019) Characteristics of spontaneous spinal cord infarction and proposed diagnostic criteria. JAMA Neurol 76(1):56–63. https://doi.org/10.1001/jamaneurol.2018.2734

    Article  PubMed  Google Scholar 

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Funding

No funds, grants, or other support were received.

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Authors

Contributions

Writing—original draft: DSO; visualization: DSO; writing—review and editing: LS; supervision: LS.

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Correspondence to Daniela Santos Oliveira.

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The authors have no relevant financial or non-financial interests to disclose.

Ethics approval

Approval was obtained from the ethics committee of Centro Hospitalar de Entre o Douro e Vouga. The procedures used in this study adhere to the tenets of the Declaration of Helsinki.

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Written informed consent was obtained from the patient.

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The participant has consented to the submission of the case report to the journal.

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Oliveira, D.S., Sousa, L. Off-label tenecteplase use in spinal cord ischemia. Acta Neurol Belg 123, 2409–2412 (2023). https://doi.org/10.1007/s13760-023-02228-8

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