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Mechanisms and Consequences of Genetic Variation in Hepatitis C Virus (HCV)
Chronic infection with hepatitis C virus (HCV) is an important contributor to the global incidence of liver diseases, including liver cirrhosis and...
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Genetic and environmental effects on morphological traits of social phenotypes in wasps
Many species exhibit distinct phenotypic classes, such as sexes in dioecious species or castes in social species. The evolution of these classes is...
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Mammarenavirus Genetic Diversity and Its Biological Implications
Members of the family Arenaviridae are classified into four genera: Antennavirus, Hartmanivirus, Mammarenavirus, and Reptarenavirus. Reptarenaviruses...
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Key triggers of adaptive genetic variability of sessile oak [Q. petraea (Matt.) Liebl.] from the Balkan refugia: outlier detection and association of SNP loci from ddRAD-seq data
Knowledge on the genetic composition of Quercus petraea in south-eastern Europe is limited despite the species’ significant role in the...
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Genetic Susceptibility to Prostate Cancer
Prostate cancer (PCa) is the second most diagnosed cancer type globally and is one of the leading causes of death in men. Genetic susceptibility...
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Genetic variability in COVID-19-related genes in the Brazilian population
SARS-CoV-2 utilizes the angiotensin-converting enzyme 2 (ACE2) receptor and transmembrane serine protease (TMPRSS2) to infect human lung cells....
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Genetic variability of human papillomavirus type 18 based on E6, E7 and L1 genes in central China
BackgroundHigh-risk human papillomavirus (HR-HPV) infection is an important factor for the development of cervical cancer. HPV18 is the second most...
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Deletion patterns, genetic variability and protein structure of pfhrp2 and pfhrp3: implications for malaria rapid diagnostic test in Amhara region, Ethiopia
BackgroundAlthough rapid diagnostic tests (RDTs) play a key role in malaria-control strategies, their efficacy has been threatened by deletion and...
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Weak Population Genetic Structure of the Eurasian Crane Grus grus L.
AbstractThe paper presents an extended (in comparison with previous studies) analysis of the population genetic structure of a migratory wide-range...
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Genetic Mosaic Analysis in Model Organisms
The definition of genetic mosaicism is the presence of cells with various genotypes within the same animal, which could be caused by somatic...
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Integrating rare genetic variants into DPYD pharmacogenetic testing may help preventing fluoropyrimidine-induced toxicity
Variability in genes involved in drug pharmacokinetics or drug response can be responsible for suboptimal treatment efficacy or predispose to adverse...
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Genetic Diversity of Human Fungal Pathogens
Purpose of ReviewFungi represent a central yet often overlooked domain of clinically relevant pathogens that have become increasingly important in...
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Population improvement via recurrent selection drives genetic gain in upland rice breeding
One of the main challenges of breeding programs is to identify superior genotypes from a large number of candidates. By gradually increasing the...
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Mitochondrial Gene Pool of Ukrainians in the Context of Variability of Whole Mitogenomes in Slavic Peoples
AbstractData on the variability of nucleotide sequences of whole mitochondrial genomes in Ukrainians were analyzed. A comparative analysis of genetic...
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Kernel-based genetic association analysis for microbiome phenotypes identifies host genetic drivers of beta-diversity
BackgroundUnderstanding human genetic influences on the gut microbiota helps elucidate the mechanisms by which genetics may influence health...
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The diversity and clinical implications of genetic variants influencing clopidogrel bioactivation and response in the Emirati population
BackgroundClopidogrel is a widely prescribed prodrug that requires activation via specific pharmacogenes to exert its anti-platelet function. Genetic...
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Polymorphism and Differentiation of Three Populations of the Evoron Vole according to the Variability of the Mitochondrial DNA Control Region
AbstractAs a result of analysis of the control region of mtDNA for the Evoron vole, a high haplotype (97%) and nucleotide (1.53%) diversity was...
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Genetic meta-analysis of levodopa induced dyskinesia in Parkinson’s disease
The genetic basis of levodopa-induced-dyskinesia (LiD) is poorly understood, and there have been few well-powered genome-wide studies. We performed a...
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Genetic Variability of the Siberian Sucker Catostomus catostomus rostratus (Teleostei: Catastomidae) from Water Bodies of the Northeast of Russia
AbstractData on the variability of the nucleotide sequence of the mtDNA cytochrome b gene and the amino acid sequence of the polypeptide encoded by...
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Shedding light on variation in reproductive success through studies of population genetic structure in a Southeast Pacific Coast mussel
Phylogeography often focuses on the spatial dimension of genetic diversity, rarely including the temporal dynamics occurring interannually among...
