-
Article
Molecular Mechanism of WWOX Inhibiting the Development of Esophageal Cancer by Inhibiting Hippo Signaling Pathway
With the emergence of combined surgical treatments, complemented by radiotherapy and chemotherapy, survival rates for esophageal cancer patients have improved, but the overall 5-year survival rate remains low....
-
Article
Open AccessImpact of baseline cardiovascular risk on the outcomes of intensive blood pressure intervention: a post hoc analysis of the China rural hypertension control project
The 2018/2023 ESC/ESH Guidelines underlined a gap how baseline cardiovascular disease (CVD) risk predicted blood pressure (BP) lowering benefits. Further, 2017 ACC/AHA Guideline and 2021 WHO Guideline recommen...
-
Article
Associations of total homocysteine and kidney function with all-cause and cause-specific mortality in hypertensive patients: a mediation and joint analysis
Plasma total homocysteine (tHcy) and kidney function are both associated with mortality risk, but the degree to which kidney function modifies the impact of tHcy on mortality remains unknown. This prospective ...
-
Article
MADMM: microservice system anomaly detection via multi-modal data and multi-feature extraction
Accurately detecting anomalies in microservice systems is crucial to avoid system failures and economic losses for users. Existing approaches detect anomalies by extracting sequential information from single-m...
-
Article
Open AccessA nomogram based on nutritional and inflammatory parameters to predict DMFS and identify beneficiaries of adjuvant chemotherapy in IVA-stage nasopharyngeal carcinoma
This study aims to develop a nomogram integrating inflammation (NLR), Prognostic Nutritional Index (PNI), and EBV DNA (tumor burden) to achieve personalized treatment and prediction for stage IVA NPC. Furtherm...
-
Article
Evaluation of urban flood adaptability based on the InVEST model and GIS: A case study of New York City, USA
Flood risk has become a serious challenge for many cities, including New York City (NYC). Evaluating urban flood adaptability evaluation is crucial for regulating storm and rain risks. In this study, we propos...
-
Article
Open AccessInfectious complications in pediatric patients undergoing CD19+CD22+ chimeric antigen receptor T-cell therapy for relapsed/refractory B-lymphoblastic leukemia
Chimeric antigen receptor T-cell (CAR-T) therapy is effective in the treatment of relapsed/refractory acute B-lymphoblastic leukemia (R/R B-ALL); however, patients who receive CAR-T therapy are predisposed to ...
-
Article
Open AccessBleomycin induces senescence and repression of DNA repair via downregulation of Rad51
Bleomycin, a potent antitumor agent, is limited in clinical use due to the potential for fatal pulmonary toxicity. The accelerated DNA damage and senescence in alveolar epithelial cells (AECs) is considered a ...
-
Article
Open AccessMachine learning-based survival prediction nomogram for postoperative parotid mucoepidermoid carcinoma
Parotid mucoepidermoid carcinoma (P-MEC) is a significant histopathological subtype of salivary gland cancer with inherent heterogeneity and complexity. Existing clinical models inadequately offer personalized...
-
Article
Open AccessConstruction of recombinant fluorescent LSDV for high-throughput screening of antiviral drugs
Lumpy skin disease virus (LSDV) infection is a major socio-economic issue that seriously threatens the global cattle-farming industry. Here, a recombinant virus LSDV-ΔTK/EGFP, expressing enhanced green fluores...
-
Article
MSCA-UNet: multi-scale channel attention-based UNet for segmentation of medical ultrasound images
Since deep learning is introduced to medical image segmentation, UNet and its variants have been extensively applied in medical image analysis. This paper proposes a multi-scale channel attention UNet (MSCA-UN...
-
Article
Financial openness and cross-border capital flows: perspectives from terrorist attacks as exogenous shocks
In an era of financial globalization, cross-border capital flows hugely affect a country’s economic conditions, but their cyclical properties remain controversial. This paper takes terrorist attacks as exogeno...
-
Article
Multifunctional and Reconfigurable Electronic Fabrics Assisted by Artificial Intelligence for Human Augmentation
Noninvasive human augmentation, namely a desirable approach for enhancing the quality of life, can be achieved through wearable electronic devices that interact with the external environment. Wearable electron...
-
Chapter and Conference Paper
A Study on the Force Comfort of Over-Ear Headphones Based on 3D Anthropometric Data
The purpose of this study is to conduct a comprehensive study on the relationship between the dimensions of over-ear headphones, the dimensions of users’ heads and ear anthropometric characteristic dimensions,...
-
Chapter and Conference Paper
Multi-patch Adversarial Attack for Remote Sensing Image Classification
Deep Neural Networks (DNNs) have shown excellent image classification performance both in accuracy and efficiency. Therefore, it is of great value to deploy adversarial patch to protect critical facilities fro...
-
Chapter and Conference Paper
A Hierarchy of Levels of Detail for 3D Utility Network Models
The paper presents a new hierarchy of multiple levels of detail (LoD) designed for the modeling of underground utility networks. The hierarchy of LoDs is applied to water management possible scenarios in the c...
-
Chapter and Conference Paper
Analysis and Validation on Multi-dimensional Assessment for Comfort of In-Ear Headphones
The comfort of in-ear headphones is becoming more and more important nowadays as people use them more frequently and for longer periods of time. Past studies related to headphones have differed in their defini...
-
Article
ROS-Activated TRPM2 Channel: Calcium Homeostasis in Cardiovascular/renal System and Speculation in Cardiorenal Syndrome
The transient receptor potential melastatin 2 (TRPM2) channel is a nonselective calcium channel that is sensitive to oxidative stress (OS), and is widely expressed in multiple organs, such as the heart, kidney...
-
Article
Long-term analysis of cellular immunity in patients with RRMM treated with CAR-T cell therapy
Chimeric antigen receptor T (CAR-T) cell therapy exhibits remarkable efficacy against refractory or relapsed multiple myeloma (RRMM); however, the immune deficiency following CAR-Ts infusion has not been well ...
-
Article
CA-GAN: the synthesis of Chinese art paintings using generative adversarial networks
With the advent of generative adversarial networks (GAN), an astonishing advancement has been made in the generation of art painting in recent years. However, existing methods still suffer problems such as col...
